Interactor 1: MCM2 (P49736)
DNA replication licensing factor MCM2 (EC 3.6.4.12) (Minichromosome maintenance protein 2 homolog) (Nuclear protein BM28)
Gene: MCM2
Interactor 2: ORC1 (Q13415)
Origin recognition complex subunit 1 (Replication control protein 1)
Gene: ORC1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.481 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 12614612 |
| Identification Methods | two hybrid |
| Interaction Type | direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0000781 - chromosome, telomeric region GO:0003677 - DNA binding GO:0003688 - DNA replication origin binding GO:0005524 - ATP binding GO:0005634 - nucleus and 5 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Last updated: 11Aug2025