HitPredict

Interactor 1: UBCD4 (P52486)
Ubiquitin-conjugating enzyme E2-22 kDa (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme 4) (Ubiquitin carrier protein) (Ubiquitin-protein ligase)
Gene: Ubc4

Interactor 2: CYHR1 (Q9VZV5)
Zinc finger TRAF-type-containing protein 1 homolog (Cysteine and histidine-rich protein 1 homolog)
Gene: CG32486

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	0.60	0.707

Property	Details
Experiments	14605208, 37061542, 22036573, unassigned2874, 38944040
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 199 Dm			1 412
+	Hs
		517286 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		ZTRF1_HUMAN (58-412): 7.76e-160: 457: 47.65
+	Dm
		912357 UBCD4_DROME (1-199): 1.99e-78: 234: 100.00		SINAL_DROME (1-251): 3.26e-74: 237: 23.17
+	Dm
		638290 UBCD4_DROME (1-199): 1.99e-78: 234: 100.00		SINA_DROME (97-298): 2.32e-51: 176: 20.94
+	Hs
		957626 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		SIAH1_HUMAN (91-298): 1.01e-50: 173: 20.00
+	Hs
		1307820 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		SIAH1_HUMAN (91-298): 1.01e-50: 173: 20.00
+	Hs
		211556 UB2D2_HUMAN (4-154): 5.95e-76: 226: 41.72		SIAH2_HUMAN (101-298): 2.78e-47: 166: 21.30
+	Hs
		957637 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		RN138_HUMAN (101-204): 1.11e-26: 108: 22.43
+	Hs
		957639 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		RN166_HUMAN (91-245): 1.42e-26: 108: 15.34
+	Hs
		982195 UB2D2_HUMAN (4-154): 5.95e-76: 226: 41.72		RN151_HUMAN (104-233): 7.64e-29: 114: 22.39
+	Hs
		1357999 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		RN138_HUMAN (101-204): 1.11e-26: 108: 22.43
+	Hs
		1382356 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		RN166_HUMAN (91-245): 1.42e-26: 108: 15.34
+	Hs
		957696 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		RN114_HUMAN (93-208): 4.4e-24: 101: 20.69
+	Hs
		1490990 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		RN114_HUMAN (93-208): 4.4e-24: 101: 20.69
+	Hs
		957623 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		TRI50_HUMAN (106-268): 2.84e-11: 66.8: 21.34
+	Hs
		957613 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		TRAF7_HUMAN (14-289): 2.43e-10: 64.5: 17.25
+	Hs
		957645 UBE2K_HUMAN (1-199): 5.49e-78: 233: 68.34		RN125_HUMAN (85-205): 2.41e-10: 62.2: 22.31
+	Hs
		1294335 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		TRI50_HUMAN (106-268): 2.84e-11: 66.8: 21.34
+	Hs
		1246181 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		TRAF7_HUMAN (14-289): 2.43e-10: 64.5: 17.25
+	Hs
		982214 UB2D2_HUMAN (4-154): 5.95e-76: 226: 41.72		TRAF7_HUMAN (14-289): 2.43e-10: 64.5: 17.25
+	Hs
		1389548 UB2D4_HUMAN (4-154): 8.38e-77: 228: 41.06		RN125_HUMAN (85-205): 2.41e-10: 62.2: 22.31