HitPredict

Interactor 1: LRP2 (P98164)
Low-density lipoprotein receptor-related protein 2 (LRP-2) (Glycoprotein 330) (gp330) (Megalin)
Gene: LRP2

Interactor 2: ANRA2 (Q9H9E1)
Ankyrin repeat family A protein 2 (RFXANK-like protein 2)
Gene: ANKRA2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.571

Property	Details
Experiments	11095640, 22649097
Identification Methods	two hybrid, pull down, affinity chromatography technology, x-ray crystallography
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 4655 Hs			1 313
+	Dm
		1362122 Q9VBN1_DROME (933-1171): 7.51e-16: 87.2: 20.32		Q9VL58_DROME (123-308): 1.36e-25: 103: 36.32
+	Hs
		992707 LRP1_HUMAN (1102-1387): 4.45e-09: 65.6: 13.59		TNKS2_HUMAN (75-306): 1.76e-30: 123: 16.26
+	Dm
		1155045 Q6NP71_DROME (167-416): 2.38e-14: 82.6: 22.27		Q9VL58_DROME (123-308): 1.36e-25: 103: 36.32
+	Hs
		270281 LRP6_HUMAN (3113-3241): 3.94e-09: 65.6: 16.30		RIPK4_HUMAN (2-179): 1.62e-24: 105: 8.11
+	Mm
		223309 LRP1_MOUSE (3672-3974): 3.08e-09: 66: 10.16		ILK_MOUSE (172-311): 1.9e-15: 78.2: 33.57