HitPredict

Interactor 1: F1RK46 (F1RK46)
histone acetyltransferase (EC 2.3.1.48)
Gene: CREBBP

Interactor 2: IRF3 (Q764M6)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Sus scrofa

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	27334592
Identification Methods	comigration in non denaturing gel electrophoresis
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Creb_binding~IRF-3
Common GO terms	-
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 2440 Ss			1 419
+	Hs
		1129165 CBP_HUMAN (1-2440): 0: 1056: 94.11		IRF3_HUMAN (1-419): 0: 591: 77.91
+	Hs
		1110875 CBP_HUMAN (1-2440): 0: 1056: 94.11		IRF5_HUMAN (2-407): 1.31e-146: 427: 29.10
+	Hs
		1037806 CBP_HUMAN (1-2440): 0: 1056: 94.11		IRF8_HUMAN (7-385): 7.3e-142: 413: 26.85
+	Hs
		1067328 EP300_HUMAN (1-2414): 0: 857: 53.72		IRF3_HUMAN (1-419): 0: 591: 77.91
+	Hs
		1368450 CBP_HUMAN (1-2440): 0: 1056: 94.11		IRF7_HUMAN (4-380): 9.98e-111: 336: 25.81
+	Mm
		74267 EP300_MOUSE (1-2414): 0: 855: 53.41		IRF3_MOUSE (1-419): 0: 528: 68.41
+	Hs
		1028135 CBP_HUMAN (1-2440): 0: 1056: 94.11		IRF9_HUMAN (7-386): 3.84e-98: 300: 24.26
+	Hs
		1067354 EP300_HUMAN (1-2414): 0: 857: 53.72		IRF4_HUMAN (7-411): 8.38e-153: 441: 27.60
+	Hs
		1067290 EP300_HUMAN (1-2414): 0: 857: 53.72		IRF5_HUMAN (2-407): 1.31e-146: 427: 29.10
+	Hs
		533958 CBP_HUMAN (1-2440): 0: 1056: 94.11		IRF1_HUMAN (1-207): 5.88e-49: 170: 25.23
+	Hs
		1067577 EP300_HUMAN (1-2414): 0: 857: 53.72		IRF7_HUMAN (4-380): 9.98e-111: 336: 25.81
+	Hs
		571599 EP300_HUMAN (1-2414): 0: 857: 53.72		IRF2_HUMAN (1-156): 1.88e-49: 173: 27.22
+	Hs
		533927 EP300_HUMAN (1-2414): 0: 857: 53.72		IRF1_HUMAN (1-207): 5.88e-49: 170: 25.23
+	Hs
		1145845 CHD7_HUMAN (1995-2424): 5.18e-11: 71: 12.25		IRF4_HUMAN (7-411): 8.38e-153: 441: 27.60
+	Hs
		1145822 KMT2C_HUMAN (1854-2275): 3.86e-09: 64.7: 12.04		IRF4_HUMAN (7-411): 8.38e-153: 441: 27.60
+	Hs
		465930 CO1A2_HUMAN (1840-2227): 2.45e-17: 91.4: 13.14		IRF2_HUMAN (1-156): 1.88e-49: 173: 27.22
+	Hs
		465928 CO1A2_HUMAN (1840-2227): 2.45e-17: 91.4: 13.14		IRF1_HUMAN (1-207): 5.88e-49: 170: 25.23