HitPredict

Interactor 1: 1433F (P68510)
14-3-3 protein eta
Gene: Ywhah

Interactor 2: MARK4 (Q8CIP4)
MAP/microtubule affinity-regulating kinase 4 (EC 2.7.11.1)
Gene: MARK4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	16959763
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Mm			1 752
+	Hs
		971885 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		MARK4_HUMAN (1-752): 0: 725: 97.61
+	Mm
		972284 1433E_MOUSE (1-244): 1.99e-141: 398: 62.71		MARK4_MOUSE (1-752): 0: 725: 100.00
+	Hs
		692031 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		MARK3_HUMAN (1-752): 0: 678: 60.37
+	Mm
		972206 1433E_MOUSE (1-244): 1.99e-141: 398: 62.71		MARK3_MOUSE (1-752): 0: 676: 60.63
+	Xl
		237423 O57468_XENLA (1-244): 1.26e-140: 396: 62.71		Q804T2_XENLA (1-752): 0: 676: 59.31
+	Xl
		237424 O57468_XENLA (1-244): 1.26e-140: 396: 62.71		Q8QGV3_XENLA (1-752): 0: 626: 49.38
+	Mm
		972209 1433E_MOUSE (1-244): 1.99e-141: 398: 62.71		MARK2_MOUSE (2-752): 0: 621: 48.62
+	Hs
		971697 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		MARK2_HUMAN (2-752): 0: 614: 48.07
+	Hs
		972078 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		MARK1_HUMAN (1-752): 0: 609: 50.44
+	Mm
		972294 1433E_MOUSE (1-244): 1.99e-141: 398: 62.71		MARK1_MOUSE (1-752): 0: 607: 50.19
+	Dm
		94942 1433E_DROME (1-243): 1.09e-140: 396: 63.37		E1JGN0_DROME (5-752): 0: 584: 45.40
+	Hs
		971530 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		MELK_HUMAN (59-752): 2.76e-170: 506: 27.40
+	Mm
		972247 1433E_MOUSE (1-244): 1.99e-141: 398: 62.71		BRSK2_MOUSE (55-504): 8.76e-150: 456: 36.85
+	Hs
		971753 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		BRSK2_HUMAN (55-504): 1.66e-149: 455: 36.85
+	Hs
		972160 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		SIK3_HUMAN (39-596): 3.76e-141: 449: 36.98
+	Hs
		972043 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		SNRK_HUMAN (54-748): 4.89e-146: 447: 24.86
+	Hs
		943639 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		SIK1_HUMAN (37-653): 6.24e-143: 440: 32.86
+	Rn
		930528 1433E_RAT (1-244): 1.99e-141: 398: 62.71		AAPK1_RAT (29-570): 2.39e-140: 426: 27.93
+	Hs
		971469 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		AAPK1_HUMAN (29-570): 2.49e-139: 423: 27.93
+	Hs
		971985 1433E_HUMAN (1-244): 1.99e-141: 398: 62.71		SIK2_HUMAN (56-367): 2.08e-104: 342: 55.17