Protein: TPPP
Tubulin polymerization-promoting protein (TPPP) (EC 3.6.5.-) (25 kDa brain-specific protein) (TPPP/p25) (p24) (p25-alpha)

Gene: TPPP
Organism: Homo sapiens
Interactions: 37
UniProt ID: O94811

Gene Ontology (top 5):
GO:0000287 - magnesium ion binding
GO:0001578 - microtubule bundle formation
GO:0003924 - GTPase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

317517

H11
Histone H1.1

3

2

High-throughput

0.662

High

317512

SYUA
Alpha-synuclein

2

0

Small-scale

0.618

High

317524

ZN114
Zinc finger protein 114

2

0

High-throughput

0.580

High

317500

TPPP
Tubulin polymerization-promoting protein

2

0

Small-scale

0.577

High

317533

HDAC6
Protein deacetylase HDAC6

2

0

Small-scale

0.577

High

317502

SEMG1
Semenogelin-1

1

1

High-throughput

0.536

High

317508

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

317516

SEMG2
Semenogelin-2

1

1

High-throughput

0.536

High

317507

H14
Histone H1.4

1

2

High-throughput

0.515

High

317510

H15
Histone H1.5

1

2

High-throughput

0.515

High

317525

DDB2
DNA damage-binding protein 2

1

1

High-throughput

0.515

High

317509

PPAP
Prostatic acid phosphatase

1

0

High-throughput

0.513

High

317515

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.513

High

317518

FADD
FAS-associated death domain protein

1

0

High-throughput

0.513

High

317521

KLH24
Kelch-like protein 24

1

0

High-throughput

0.513

High

317529

SPTN4
Spectrin beta chain, non-erythrocytic 4

1

0

High-throughput

0.513

High

317530

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.513

High

317531

GRPE1
GrpE protein homolog 1, mitochondrial

1

0

High-throughput

0.513

High

317532

MA2C1
Alpha-mannosidase 2C1

1

0

High-throughput

0.513

High

317534

PPCT
Phosphatidylcholine transfer protein

1

0

High-throughput

0.513

High

317526

DYL2
Dynein light chain 2, cytoplasmic

1

0

Small-scale

0.504

High

317504

HMGN2
Non-histone chromosomal protein HMG-17

1

0

High-throughput

0.493

High

317513

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

0

High-throughput

0.493

High

317523

MAGB6
Melanoma-associated antigen B6

1

0

High-throughput

0.493

High

317520

DCA10
DDB1- and CUL4-associated factor 10

1

1

High-throughput

0.489

High

317503

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.480

High

317505

TBB5
Tubulin beta chain

1

0

Small-scale

0.480

High

317519

ROCK1
Rho-associated protein kinase 1

1

0

Small-scale

0.480

High

317527

MLP3B
Microtubule-associated protein 1 light chain 3 beta

1

0

Small-scale

0.480

High

317511

CD11B
Cyclin-dependent kinase 11B

1

0

High-throughput

0.460

High

317514

TISD
mRNA decay activator protein ZFP36L2

1

0

High-throughput

0.458

High

317522

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

317528

CHST5
Carbohydrate sulfotransferase 5

1

0

High-throughput

0.279

Low

104988

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

317501

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

317506

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025