Protein: MIPEP
Mitochondrial intermediate peptidase (MIP) (EC 3.4.24.59)

Gene: MIPEP
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q99797

Gene Ontology (top 5):
GO:0004222 - metalloendopeptidase activity
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0006518 - peptide metabolic process
GO:0006627 - protein processing involved in protein targeting to mitochondrion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1234499

MRM1
rRNA methyltransferase 1, mitochondrial

3

0

High-throughput

0.638

High

1407325

MGME1
Mitochondrial genome maintenance exonuclease 1

3

0

High-throughput

0.634

High

221959

FOXS1
Forkhead box protein S1

3

1

High-throughput

0.609

High

1251595

HSDL2
Hydroxysteroid dehydrogenase-like protein 2

2

0

High-throughput

0.602

High

1407326

ADPGK
ADP-dependent glucokinase

2

0

High-throughput

0.602

High

1407328

TMM70
Transmembrane protein 70, mitochondrial

2

0

High-throughput

0.602

High

777628

HMGCL
Hydroxymethylglutaryl-CoA lyase, mitochondrial

2

0

High-throughput

0.576

High

1407329

TR61B
tRNA

2

0

High-throughput

0.576

High

1198968

ACSM3
Acyl-coenzyme A synthetase ACSM3, mitochondrial

1

1

High-throughput

0.536

High

1238410

ACSM5
Acyl-coenzyme A synthetase ACSM5, mitochondrial

1

1

High-throughput

0.536

High

1310339

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

1407327

MYL10
Myosin regulatory light chain 10

1

1

High-throughput

0.536

High

303692

JTB
Protein JTB

1

0

High-throughput

0.513

High

690540

KAD4
Adenylate kinase 4, mitochondrial

1

0

High-throughput

0.513

High

733989

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

0

High-throughput

0.513

High

1214365

SYT6
Synaptotagmin-6

1

0

High-throughput

0.513

High

1216545

STPG1
O(6)-methylguanine-induced apoptosis 2

1

0

High-throughput

0.513

High

1240322

RUSD3
Mitochondrial mRNA pseudouridine synthase RPUSD3

1

0

High-throughput

0.513

High

1242613

FAHD1
Oxaloacetate tautomerase FAHD1, mitochondrial

1

0

High-throughput

0.513

High

1403394

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.513

High

1407334

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.513

High

1407336

SYYM
Tyrosine--tRNA ligase, mitochondrial

1

0

High-throughput

0.513

High

403085

REL2
Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

1

High-throughput

0.489

High

574010

HXB3
Homeobox protein Hox-B3

1

1

High-throughput

0.489

High

1114115

CUL3
Cullin-3

1

2

High-throughput

0.489

High

1186850

KR196
Keratin-associated protein 19-6

1

1

High-throughput

0.489

High

1187910

KR197
Keratin-associated protein 19-7

1

1

High-throughput

0.489

High

242711

PRKN
E3 ubiquitin-protein ligase parkin

1

4

High-throughput

0.479

High

1359844

GAB3
GRB2-associated-binding protein 3

1

1

High-throughput

0.470

High

143901

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.458

High

401365

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

505451

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

1383545

MCUR1
Mitochondrial calcium uniporter regulator 1

1

0

High-throughput

0.458

High

1407333

PAK5
Serine/threonine-protein kinase PAK 5

1

0

High-throughput

0.458

High

1209562

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

1

High-throughput

0.445

High

589510

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

696322

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

768993

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1255234

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1407337

SIR4
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial

1

0

High-throughput

0.426

High

517308

GAGE1
G antigen 1

1

1

High-throughput

0.407

High

1327586

WDTC1
WD and tetratricopeptide repeats protein 1

3

0

High-throughput

0.345

High

1290264

Q86V94
LOC554223 protein

3

0

High-throughput

0.342

High

628592

ISK2
Serine protease inhibitor Kazal-type 2

2

0

High-throughput

0.328

High

1030837

DEF6
Defensin-6

2

0

High-throughput

0.328

High

1178975

EX3L2
Exocyst complex component 3-like protein 2

2

0

High-throughput

0.328

High

1310018

FXRD2
FAD-dependent oxidoreductase domain-containing protein 2

2

0

High-throughput

0.328

High

1384942

TRI43
Tripartite motif-containing protein 43

2

0

High-throughput

0.328

High

1407331

C42S1
CDC42 small effector protein 1

2

0

High-throughput

0.328

High

1157250

AINX
Alpha-internexin

2

0

High-throughput

0.319

High

1123787

DCTN1
Dynactin subunit 1

2

0

High-throughput

0.313

High

210338

PHF1
PHD finger protein 1

1

0

High-throughput

0.279

Low

372958

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.279

Low

484828

HXB7
Homeobox protein Hox-B7

1

0

High-throughput

0.279

Low

720630

GRPR
Gastrin-releasing peptide receptor

1

0

High-throughput

0.279

Low

837378

ASIP
Agouti-signaling protein

1

0

High-throughput

0.279

Low

1022460

IDD
Integral membrane protein DGCR2/IDD

1

0

High-throughput

0.279

Low

1150313

TAF1C
TATA box-binding protein-associated factor RNA polymerase I subunit C

1

0

High-throughput

0.279

Low

1187743

KR133
Keratin-associated protein 13-3

1

0

High-throughput

0.279

Low

1331061

F169B
Protein FAM169BP

1

0

High-throughput

0.279

Low

1334823

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.279

Low

1407330

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.279

Low

843911

HD
Huntingtin

1

0

High-throughput

0.269

Low

1104469

ILK
Scaffold protein ILK

1

0

High-throughput

0.265

Low

1161199

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.265

Low

1132926

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.249

Low

1294818

STX12
Syntaxin-12

1

0

High-throughput

0.249

Low

1332468

FA47B
Protein FAM47B

1

0

High-throughput

0.249

Low

1407335

XPO7
Exportin-7

1

0

High-throughput

0.249

Low

378787

LV657
Immunoglobulin lambda variable 6-57

1

0

High-throughput

0.232

Low

516927

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low

1116690

RIN1
Ras and Rab interactor 1

1

0

High-throughput

0.232

Low

1350591

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.232

Low

1380951

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

High-throughput

0.232

Low

1407332

PP4RL
Putative serine/threonine-protein phosphatase 4 regulatory subunit 1-like

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025