Protein: HPS3
BLOC-2 complex member HPS3 (Hermansky-Pudlak syndrome 3 protein)

Gene: HPS3
Organism: Homo sapiens
Interactions: 45
UniProt ID: Q969F9

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0031084 - BLOC-2 complex
GO:0043473 - pigmentation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1295649

HPS6
BLOC-2 complex member HPS6

2

0

High-throughput

0.602

High

901986

RAB9A
Ras-related protein Rab-9A

2

1

High-throughput

0.584

High

1125586

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

1

High-throughput

0.536

High

72426

MI4GD
MIF4G domain-containing protein

1

0

High-throughput

0.513

High

295619

CIB2
Calcium and integrin-binding family member 2

1

0

High-throughput

0.513

High

296811

ST1C4
Sulfotransferase 1C4

1

0

High-throughput

0.513

High

334223

ATG7
Ubiquitin-like modifier-activating enzyme ATG7

1

0

High-throughput

0.513

High

359854

DYR
Dihydrofolate reductase

1

0

High-throughput

0.513

High

712252

TKT
Transketolase

1

0

High-throughput

0.513

High

783635

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

1

0

High-throughput

0.513

High

1064590

HDHD1
Pseudouridine-5'-phosphatase

1

0

High-throughput

0.513

High

1207245

SOLH1
Spermatogenesis- and oogenesis-specific basic helix-loop-helix-containing protein 1

1

0

High-throughput

0.513

High

1379916

ARMC5
Armadillo repeat-containing protein 5

1

0

High-throughput

0.513

High

1379921

DUS16
Dual specificity protein phosphatase 16

1

0

High-throughput

0.513

High

1379924

HPS5
BLOC-2 complex member HPS5

1

0

High-throughput

0.513

High

901457

RAB7A
Ras-related protein Rab-7a

1

1

High-throughput

0.479

High

1106027

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

1

High-throughput

0.479

High

138260

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

0

High-throughput

0.458

High

342996

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

1292793

SKAP1
Src kinase-associated phosphoprotein 1

1

0

High-throughput

0.458

High

1379922

CHIA
Acidic mammalian chitinase

1

0

High-throughput

0.458

High

1379923

XPO7
Exportin-7

1

0

High-throughput

0.458

High

352634

TCL1B
T-cell leukemia/lymphoma protein 1B

3

0

High-throughput

0.347

High

261536

B4GT2
Beta-1,4-galactosyltransferase 2

1

0

High-throughput

0.279

Low

289797

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

366427

FA12
Coagulation factor XII

1

0

High-throughput

0.279

Low

1177054

INF2
Inverted formin-2

1

0

High-throughput

0.279

Low

1254334

S2548
Solute carrier family 25 member 48

1

0

High-throughput

0.279

Low

1323918

KLH34
Kelch-like protein 34

1

0

High-throughput

0.279

Low

1325814

D2HDH
D-2-hydroxyglutarate dehydrogenase, mitochondrial

1

0

High-throughput

0.279

Low

1329799

SIR6
NAD-dependent protein deacylase sirtuin-6

1

0

High-throughput

0.279

Low

1379917

LOXL4
Lysyl oxidase homolog 4

1

0

High-throughput

0.279

Low

1379918

F167A
Protein FAM167A

1

0

High-throughput

0.279

Low

1379919

PPM1M
Protein phosphatase 1M

1

0

High-throughput

0.279

Low

888475

TSP3
Thrombospondin-3

1

0

High-throughput

0.249

Low

914461

EFNB2
Ephrin-B2

1

0

High-throughput

0.249

Low

1366958

ESR2
Estrogen receptor beta

1

0

High-throughput

0.249

Low

1379920

YI001
Uncharacterized protein FLJ30774

1

0

High-throughput

0.249

Low

516926

CB27B
Putative uncharacterized protein CDRT15P3

1

0

High-throughput

0.232

Low

1010961

BAT1
b(0,+)-type amino acid transporter 1

1

0

High-throughput

0.232

Low

1070450

ZNFS1
Putative uncharacterized protein ZNF252P-AS1

1

0

High-throughput

0.232

Low

1185860

NSN5B
Putative NOL1/NOP2/Sun domain family member 5B

1

0

High-throughput

0.232

Low

1329179

S15A4
Solute carrier family 15 member 4

1

0

High-throughput

0.232

Low

1332130

CI163
Uncharacterized protein C9orf163

1

0

High-throughput

0.232

Low

1379925

S27A6
Long-chain fatty acid transport protein 6

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025