Protein: AP1S2
AP-1 complex subunit sigma-2 (Adaptor protein complex AP-1 subunit sigma-1B) (Adaptor-related protein complex 1 subunit sigma-1B) (Clathrin assembly protein complex 1 sigma-1B small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1B subunit) (Sigma 1B subunit of AP-1 clathrin) (Sigma-adaptin 1B) (Sigma1B-adaptin)

Gene: AP1S2
Organism: Homo sapiens
Interactions: 52
UniProt ID: P56377

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005765 - lysosomal membrane
GO:0005769 - early endosome
GO:0005794 - Golgi apparatus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

212611

AP1G1
AP-1 complex subunit gamma-1

6

20

Small-scale

0.958

High

276360

AP1G2
AP-1 complex subunit gamma-like 2

4

20

Small-scale

0.905

High

880408

AP2B1
AP-2 complex subunit beta

3

20

High-throughput

0.871

High

880409

AP1B1
AP-1 complex subunit beta-1

3

20

High-throughput

0.871

High

880428

AP1M1
AP-1 complex subunit mu-1

3

20

High-throughput

0.871

High

880423

AP2M1
AP-2 complex subunit mu

3

20

High-throughput

0.861

High

880436

AP1M2
AP-1 complex subunit mu-2

3

20

High-throughput

0.861

High

880411

EPN4
Clathrin interactor 1

3

4

High-throughput

0.675

High

880413

AP1AR
AP-1 complex-associated regulatory protein

3

1

High-throughput

0.675

High

880417

AFTIN
Aftiphilin

3

1

High-throughput

0.675

High

880430

HTR5B
HEAT repeat-containing protein 5B

3

5

High-throughput

0.675

High

880432

SYNRG
Synergin gamma

3

1

High-throughput

0.675

High

880415

AAGAB
Alpha- and gamma-adaptin-binding protein p34

3

2

High-throughput

0.667

High

207549

RNF13
E3 ubiquitin-protein ligase RNF13

2

4

High-throughput

0.628

High

257171

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

2

4

High-throughput

0.628

High

880431

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

1

High-throughput

0.628

High

880433

STX8
Syntaxin-8

2

3

High-throughput

0.628

High

880407

AP1S1
AP-1 complex subunit sigma-1A

1

15

High-throughput

0.618

High

880405

CAV3
Caveolin-3

2

0

High-throughput

0.602

High

880435

MB212
Protein mab-21-like 2

2

2

High-throughput

0.553

High

451407

CLCA
Clathrin light chain A

1

7

High-throughput

0.536

High

602512

COMT
Catechol O-methyltransferase

1

3

High-throughput

0.536

High

878159

SEC13
Protein SEC13 homolog

1

3

High-throughput

0.536

High

880406

UBC12
NEDD8-conjugating enzyme Ubc12

1

2

High-throughput

0.536

High

880418

NBEL1
Neurobeachin-like protein 1

1

1

High-throughput

0.536

High

880424

SPT33
Spermatogenesis-associated protein 33

1

2

High-throughput

0.536

High

880414

TENS2
Tensin-2

2

3

High-throughput

0.526

High

329098

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

0

High-throughput

0.513

High

799898

ABCG1
ATP-binding cassette sub-family G member 1

1

0

High-throughput

0.513

High

880427

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.513

High

880434

NOP58
Nucleolar protein 58

1

0

High-throughput

0.513

High

48864

POTB3
POTE ankyrin domain family member B3

2

4

High-throughput

0.504

High

452702

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

4

High-throughput

0.489

High

679437

CPSM
Carbamoyl-phosphate synthase [ammonia], mitochondrial

1

1

High-throughput

0.489

High

880416

POTEG
POTE ankyrin domain family member G

1

2

High-throughput

0.489

High

880425

TIM29
Mitochondrial import inner membrane translocase subunit Tim29

1

1

High-throughput

0.489

High

162555

XPO1
Exportin-1

1

16

High-throughput

0.479

High

226996

PRKN
E3 ubiquitin-protein ligase parkin

1

13

High-throughput

0.479

High

303056

HEXI1
Protein HEXIM1

1

5

High-throughput

0.479

High

338197

EGFR
Epidermal growth factor receptor

1

12

High-throughput

0.479

High

880420

ATG9A
Autophagy-related protein 9A

1

7

High-throughput

0.479

High

880422

RN149
E3 ubiquitin-protein ligase RNF149

1

4

High-throughput

0.479

High

880429

DCA13
DDB1- and CUL4-associated factor 13

1

3

Small-scale

0.479

High

496667

TAU
Microtubule-associated protein tau

1

14

High-throughput

0.445

High

880412

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

5

High-throughput

0.445

High

880410

TIF1B
Transcription intermediary factor 1-beta

1

5

High-throughput

0.437

High

880419

TRI67
Tripartite motif-containing protein 67

1

7

High-throughput

0.437

High

880421

S43A3
Equilibrative nucleobase transporter 1

1

1

High-throughput

0.437

High

92813

E9PS74
Solute carrier family 43 member 3

1

1

High-throughput

0.407

High

880426

CCM2
Cerebral cavernous malformations 2 protein

2

0

High-throughput

0.328

High

121623

CORT
Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]

1

0

High-throughput

0.279

Low

750572

VKGC
Vitamin K-dependent gamma-carboxylase

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024