Protein: S12A4
Solute carrier family 12 member 4 (Electroneutral potassium-chloride cotransporter 1) (Erythroid K-Cl cotransporter 1) (hKCC1)

Gene: S12A4, SLC12A4
Organism: Homo sapiens
Interactions: 119
UniProt ID: Q9UP95

Gene Ontology (top 5):
GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0006811 - monoatomic ion transport
GO:0006884 - cell volume homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1355610

S12A6
Solute carrier family 12 member 6

1

5

High-throughput

0.691

High

1357634

S12A7
Solute carrier family 12 member 7

1

4

High-throughput

0.691

High

121232

LEG8
Galectin-8

3

20

High-throughput

0.667

High

572481

LEG3
Galectin-3

3

20

High-throughput

0.667

High

1079804

EREP1
Endosomal transmembrane epsin interactor 1

3

4

High-throughput

0.667

High

350688

RASK
GTPase KRas

3

20

High-throughput

0.640

High

1205323

LYPD6
Ly6/PLAUR domain-containing protein 6

3

0

High-throughput

0.638

High

121541

TR10A
Tumor necrosis factor receptor superfamily member 10A

2

3

High-throughput

0.628

High

134688

NPT3
Sodium-dependent phosphate transport protein 3

2

3

High-throughput

0.628

High

989661

ACHD
Acetylcholine receptor subunit delta

2

3

High-throughput

0.628

High

1305576

GPR21
Probable G-protein coupled receptor 21

2

8

High-throughput

0.628

High

1342644

NRN1
Neuritin

2

2

High-throughput

0.628

High

1357633

PCDA3
Protocadherin alpha-3

2

1

High-throughput

0.628

High

976381

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

10

High-throughput

0.611

High

119565

LEG9
Galectin-9

3

20

High-throughput

0.609

High

1150404

LEG9C
Galectin-9C

3

20

High-throughput

0.609

High

1238431

TM102
Transmembrane protein 102

2

1

High-throughput

0.606

High

1239081

I17RC
Interleukin-17 receptor C

2

0

High-throughput

0.602

High

349734

RASH
GTPase HRas

2

20

High-throughput

0.584

High

1357627

S12A4
Solute carrier family 12 member 4

1

5

Small-scale

0.584

High

1357629

AP3M1
AP-3 complex subunit mu-1

2

0

High-throughput

0.580

High

1222796

M21D2
Nucleotidyltransferase MB21D2

2

3

High-throughput

0.553

High

179281

COPT1
High affinity copper uptake protein 1

1

2

High-throughput

0.536

High

234062

O10H2
Olfactory receptor 10H2

1

11

High-throughput

0.536

High

504965

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.536

High

513765

CP19A
Aromatase

1

3

High-throughput

0.536

High

736161

ACHA7
Neuronal acetylcholine receptor subunit alpha-7

1

3

High-throughput

0.536

High

944008

X3CL1
Fractalkine

1

1

High-throughput

0.536

High

946454

EREP3
Protein ENTREP3

1

4

High-throughput

0.536

High

1086138

AMHR2
Anti-Muellerian hormone type-2 receptor

1

3

High-throughput

0.536

High

1117575

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

2

High-throughput

0.536

High

1125168

TTMP
TPA-induced transmembrane protein

1

4

High-throughput

0.536

High

1137085

OR2G6
Olfactory receptor 2G6

1

3

High-throughput

0.536

High

1189769

TMC4
Transmembrane channel-like protein 4

1

2

High-throughput

0.536

High

1235216

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

4

High-throughput

0.536

High

1245408

OR4N2
Olfactory receptor 4N2

1

9

High-throughput

0.536

High

1245417

O52I1
Olfactory receptor 52I1

1

4

High-throughput

0.536

High

1245418

OR5L1
Olfactory receptor 5L1

1

3

High-throughput

0.536

High

1245439

OR6T1
Olfactory receptor 6T1

1

4

High-throughput

0.536

High

1245444

O10S1
Olfactory receptor 10S1

1

11

High-throughput

0.536

High

1253740

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

4

High-throughput

0.536

High

1329933

TTYH1
Protein tweety homolog 1

1

5

High-throughput

0.536

High

1335628

RXFP1
Relaxin receptor 1

1

5

High-throughput

0.536

High

1342556

KCMB3
Calcium-activated potassium channel subunit beta-3

1

1

High-throughput

0.536

High

1343108

TMM9B
Transmembrane protein 9B

1

1

High-throughput

0.536

High

1344891

PCDBG
Protocadherin beta-16

1

4

High-throughput

0.536

High

1357631

O10H1
Olfactory receptor 10H1

1

11

High-throughput

0.536

High

1357632

PCDGL
Protocadherin gamma-C4

1

4

High-throughput

0.536

High

1357635

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

2

High-throughput

0.536

High

364479

TFR1
Transferrin receptor protein 1

1

1

High-throughput

0.515

High

1317784

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.513

High

825761

MTR1B
Melatonin receptor type 1B

1

3

High-throughput

0.508

High

49500

CLRN2
Clarin-2

1

3

High-throughput

0.489

High

161171

CLGN
Calmegin

1

6

High-throughput

0.489

High

296235

DPM2
Dolichol phosphate-mannose biosynthesis regulatory protein

1

2

High-throughput

0.489

High

739570

DHB3
17-beta-hydroxysteroid dehydrogenase type 3

1

1

High-throughput

0.489

High

1053841

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

3

High-throughput

0.489

High

1107988

LEG9B
Galectin-9B

1

20

High-throughput

0.489

High

1292730

ZDH12
Palmitoyltransferase ZDHHC12

1

8

High-throughput

0.489

High

1345123

RAB6B
Ras-related protein Rab-6B

1

20

High-throughput

0.489

High

1350282

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

4

High-throughput

0.489

High

120715

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

127072

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

1

High-throughput

0.479

High

169667

BET1
BET1 homolog

1

9

High-throughput

0.479

High

178864

STX7
Syntaxin-7

1

13

High-throughput

0.479

High

206171

TGON2
Trans-Golgi network integral membrane protein 2

1

5

High-throughput

0.479

High

213062

STX6
Syntaxin-6

1

9

High-throughput

0.479

High

318254

DIRA3
GTP-binding protein Di-Ras3

1

11

High-throughput

0.479

High

349008

RASN
GTPase NRas

1

20

High-throughput

0.479

High

434077

LYN
Tyrosine-protein kinase Lyn

1

7

Small-scale

0.479

High

436575

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.479

High

527888

LAMP2
Lysosome-associated membrane glycoprotein 2

1

13

High-throughput

0.479

High

545701

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.479

High

564740

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

567329

CXA1
Gap junction alpha-1 protein

1

9

High-throughput

0.479

High

592063

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.479

High

592582

RAB5A
Ras-related protein Rab-5A

1

20

High-throughput

0.479

High

793529

MUC18
Cell surface glycoprotein MUC18

1

2

High-throughput

0.479

High

844800

RAB5C
Ras-related protein Rab-5C

1

20

High-throughput

0.479

High

845356

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.479

High

852677

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.479

High

892682

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

894592

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.479

High

895321

RAB2A
Ras-related protein Rab-2A

1

20

High-throughput

0.479

High

901055

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

913189

ARF6
ADP-ribosylation factor 6

1

8

High-throughput

0.479

High

916077

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.479

High

925735

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

951460

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

1070458

RAB35
Ras-related protein Rab-35

1

11

High-throughput

0.479

High

1076816

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.479

High

1152194

LTOR1
Ragulator complex protein LAMTOR1

1

6

High-throughput

0.479

High

1183612

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.479

High

1237521

CGAS
Cyclic GMP-AMP synthase

1

3

High-throughput

0.479

High

1269255

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.479

High

1330991

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.479

High

1335397

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

1349721

TM216
Transmembrane protein 216

1

2

High-throughput

0.479

High

1357628

LAMP3
Lysosome-associated membrane glycoprotein 3

1

13

High-throughput

0.479

High

129856

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

0

High-throughput

0.458

High

339138

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.445

High

914461

RB11A
Ras-related protein Rab-11A

1

5

High-throughput

0.437

High

1172279

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

1203907

TMM17
Transmembrane protein 17

1

6

High-throughput

0.437

High

1296961

SNX27
Sorting nexin-27

1

3

High-throughput

0.437

High

1346211

OTULL
Inactive ubiquitin thioesterase OTULINL

1

1

High-throughput

0.437

High

1354870

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.437

High

387746

P53
Cellular tumor antigen p53

1

2

High-throughput

0.407

High

67401

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

887443

KR122
Keratin-associated protein 12-2

2

0

High-throughput

0.316

High

1109098

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

1236862

ZN655
Zinc finger protein 655

2

0

High-throughput

0.316

High

1316605

CNFN
Cornifelin

2

0

High-throughput

0.316

High

1234952

JAGN1
Protein jagunal homolog 1

1

0

High-throughput

0.279

Low

1146963

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.249

Low

1356973

PPM1H
Protein phosphatase 1H

1

0

High-throughput

0.249

Low

1357630

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low

1167136

MCAF1
Activating transcription factor 7-interacting protein 1

1

0

High-throughput

0.238

Low


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Last updated: 15 Jul 2024