Protein: LUM
Lumican (Keratan sulfate proteoglycan lumican) (KSPG lumican)

Gene: LUM
Organism: Homo sapiens
Interactions: 41
UniProt ID: P51884

Gene Ontology (top 5):
GO:0005201 - extracellular matrix structural constituent
GO:0005518 - collagen binding
GO:0005576 - extracellular region
GO:0005583 - fibrillar collagen trimer
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

908600

RHOA
Transforming protein RhoA

2

15

High-throughput

0.811

High

908603

PTN11
Tyrosine-protein phosphatase non-receptor type 11

2

5

High-throughput

0.726

High

908620

LRC40
Leucine-rich repeat-containing protein 40

2

20

High-throughput

0.726

High

603211

KPCA
Protein kinase C alpha type

1

2

High-throughput

0.665

High

908613

LMO3
LIM domain only protein 3

1

0

High-throughput

0.630

High

317557

SLIT2
Slit homolog 2 protein

1

19

High-throughput

0.618

High

378967

PIGR
Polymeric immunoglobulin receptor

1

2

Small-scale

0.618

High

400515

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

20

High-throughput

0.618

High

748689

CGL
Cystathionine gamma-lyase

2

0

High-throughput

0.602

High

894403

MMP14
Matrix metalloproteinase-14

2

0

Small-scale

0.598

High

125336

LEG9
Galectin-9

2

6

High-throughput

0.571

High

908612

LRC47
Leucine-rich repeat-containing protein 47

1

20

High-throughput

0.553

High

893470

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

0

High-throughput

0.518

High

908601

1433G
14-3-3 protein gamma

1

3

High-throughput

0.515

High

908610

KLH22
Kelch-like protein 22

1

1

High-throughput

0.514

High

421757

A4
Amyloid-beta precursor protein

1

6

Small-scale

0.501

High

563455

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.494

High

908615

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.493

High

908609

LEG9B
Galectin-9B

1

6

High-throughput

0.489

High

908604

EXOS9
Exosome complex component RRP45

1

2

High-throughput

0.479

High

908605

CUL3
Cullin-3

1

1

High-throughput

0.479

High

908608

SETB1
Histone-lysine N-methyltransferase SETDB1

1

1

High-throughput

0.470

High

460789

CATB
Cathepsin B

1

0

Small-scale

0.458

High

590841

TIMP2
Metalloproteinase inhibitor 2

1

0

High-throughput

0.458

High

872095

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

480746

LEG1
Galectin-1

1

6

High-throughput

0.445

High

609630

LEG3
Galectin-3

1

6

High-throughput

0.445

High

217985

TGON2
Trans-Golgi network integral membrane protein 2

1

3

High-throughput

0.437

High

908607

EXOS7
Exosome complex component RRP42

1

2

High-throughput

0.437

High

908621

EXOS4
Exosome complex component RRP41

1

1

High-throughput

0.437

High

908623

TRI17
E3 ubiquitin-protein ligase TRIM17

1

1

Small-scale

0.437

High

908622

THUM1
THUMP domain-containing protein 1

2

0

High-throughput

0.328

High

908614

UBCP1
Ubiquitin-like domain-containing CTD phosphatase 1

1

0

High-throughput

0.279

Low

908618

ZN488
Zinc finger protein 488

1

0

High-throughput

0.279

Low

908619

ILKAP
Integrin-linked kinase-associated serine/threonine phosphatase 2C

1

0

High-throughput

0.279

Low

908606

EXOS2
Exosome complex component RRP4

1

0

High-throughput

0.249

Low

908616

RMD1
Regulator of microtubule dynamics protein 1

1

0

High-throughput

0.249

Low

908617

RSRC1
Serine/Arginine-related protein 53

1

0

High-throughput

0.249

Low

908602

TRA2B
Transformer-2 protein homolog beta

1

0

High-throughput

0.238

Low

346620

TTC4
Tetratricopeptide repeat protein 4

1

0

High-throughput

0.232

Low

908611

NRM
Nurim

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025