Protein: GUCD1
Protein GUCD1 (Guanylyl cyclase domain-containing protein 1) (Protein LLN4)

Gene: GUCD1
Organism: Homo sapiens
Interactions: 91
UniProt ID: Q96NT3

Gene Ontology (top 5):
GO:0051591 - response to cAMP
GO:0097421 - liver regeneration

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

74362

ZBT42
Zinc finger and BTB domain-containing protein 42

2

1

High-throughput

0.553

High

885371

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.553

High

950631

KR108
Keratin-associated protein 10-8

2

7

High-throughput

0.553

High

950868

KR109
Keratin-associated protein 10-9

2

7

High-throughput

0.553

High

1059721

KRA11
Keratin-associated protein 1-1

2

7

High-throughput

0.553

High

1177918

RSPO4
R-spondin-4

2

1

High-throughput

0.553

High

1215150

LCE2A
Late cornified envelope protein 2A

2

1

High-throughput

0.553

High

1215225

LCE2D
Late cornified envelope protein 2D

2

1

High-throughput

0.553

High

1235804

KRA57
Keratin-associated protein 5-7

2

7

High-throughput

0.553

High

1244210

MORN3
MORN repeat-containing protein 3

2

1

High-throughput

0.553

High

1330211

ZN655
Zinc finger protein 655

2

1

High-throughput

0.553

High

1336578

MORN4
MORN repeat-containing protein 4

2

1

High-throughput

0.553

High

1399220

KRA98
Keratin-associated protein 9-8

2

7

High-throughput

0.553

High

1399221

KRA92
Keratin-associated protein 9-2

2

7

High-throughput

0.553

High

1399222

KRA42
Keratin-associated protein 4-2

2

7

High-throughput

0.553

High

1399223

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.553

High

1399224

KRA32
Keratin-associated protein 3-2

2

1

High-throughput

0.553

High

1399225

KRA15
Keratin-associated protein 1-5

2

7

High-throughput

0.553

High

1399231

HESX1
Homeobox expressed in ES cells 1

2

2

High-throughput

0.553

High

210095

CRX
Cone-rod homeobox protein

1

1

High-throughput

0.523

High

950377

KR107
Keratin-associated protein 10-7

1

7

High-throughput

0.523

High

2820

A0A0C3SFZ9
FCH and mu domain containing endocytic adaptor 1

1

1

High-throughput

0.470

High

1232528

Q6FHY5
MEOX2 protein

1

1

High-throughput

0.470

High

551207

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

155690

FCHO1
F-BAR domain only protein 1

1

1

High-throughput

0.439

High

894104

MEOX2
Homeobox protein MOX-2

1

1

High-throughput

0.439

High

1394399

NGLY1
Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase

4

0

High-throughput

0.364

High

748707

CGL
Cystathionine gamma-lyase

3

0

High-throughput

0.352

High

635367

IMDH1
Inosine-5'-monophosphate dehydrogenase 1

2

0

High-throughput

0.328

High

1399217

GORS1
Golgi reassembly-stacking protein 1

2

0

High-throughput

0.328

High

159085

LCE2B
Late cornified envelope protein 2B

2

0

High-throughput

0.320

High

70430

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

165189

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

209906

ADA12
Disintegrin and metalloproteinase domain-containing protein 12

2

0

High-throughput

0.316

High

221389

SPY1
Protein sprouty homolog 1

2

0

High-throughput

0.316

High

509952

Z705D
Zinc finger protein 705D

2

0

High-throughput

0.316

High

585088

ZN250
Zinc finger protein 250

2

0

High-throughput

0.316

High

680992

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.316

High

892230

MCSP
Sperm mitochondrial-associated cysteine-rich protein

2

0

High-throughput

0.316

High

1006289

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.316

High

1037114

ID3
DNA-binding protein inhibitor ID-3

2

0

High-throughput

0.316

High

1042776

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

0

High-throughput

0.316

High

1097107

MP2K5
Dual specificity mitogen-activated protein kinase kinase 5

2

0

High-throughput

0.316

High

1116565

FHL3
Four and a half LIM domains protein 3

2

0

High-throughput

0.316

High

1117063

RUNX3
Runt-related transcription factor 3

2

0

High-throughput

0.316

High

1133153

LASP1
LIM and SH3 domain protein 1

2

0

High-throughput

0.316

High

1181586

NDUF6
NADH dehydrogenase

2

0

High-throughput

0.316

High

1186849

KR196
Keratin-associated protein 19-6

2

0

High-throughput

0.316

High

1186905

KR195
Keratin-associated protein 19-5

2

0

High-throughput

0.316

High

1187740

KR133
Keratin-associated protein 13-3

2

0

High-throughput

0.316

High

1193099

DRC12
Dynein regulatory complex protein 12

2

0

High-throughput

0.316

High

1213812

KPRP
Keratinocyte proline-rich protein

2

0

High-throughput

0.316

High

1213916

LCE1C
Late cornified envelope protein 1C

2

0

High-throughput

0.316

High

1232112

VASN
Vasorin

2

0

High-throughput

0.316

High

1235841

KRA56
Keratin-associated protein 5-6

2

0

High-throughput

0.316

High

1250289

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

1254335

S2548
Solute carrier family 25 member 48

2

0

High-throughput

0.316

High

1280272

AP2D
Transcription factor AP-2-delta

2

0

High-throughput

0.316

High

1287724

ISCA2
Iron-sulfur cluster assembly 2 homolog, mitochondrial

2

0

High-throughput

0.316

High

1311457

TRI42
Tripartite motif-containing protein 42

2

0

High-throughput

0.316

High

1329082

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

2

0

High-throughput

0.316

High

1348438

LNX1
E3 ubiquitin-protein ligase LNX

2

0

High-throughput

0.316

High

1359060

ZCH13
Zinc finger CCHC domain-containing protein 13

2

0

High-throughput

0.316

High

1369100

PCSK5
Proprotein convertase subtilisin/kexin type 5

2

0

High-throughput

0.316

High

1398689

AP4AT
AP-4 complex accessory subunit Tepsin

2

0

High-throughput

0.316

High

1399214

SYGP1
Ras/Rap GTPase-activating protein SynGAP

2

0

High-throughput

0.316

High

1399215

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.316

High

1399216

THIOM
Thioredoxin, mitochondrial

2

0

High-throughput

0.316

High

1399218

FUCO2
Plasma alpha-L-fucosidase

2

0

High-throughput

0.316

High

1399219

BEGIN
Brain-enriched guanylate kinase-associated protein

2

0

High-throughput

0.316

High

1399226

KTBL1
KATNB1-like protein 1

2

0

High-throughput

0.316

High

1399227

TOLIP
Toll-interacting protein

2

0

High-throughput

0.316

High

1399228

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

2

0

High-throughput

0.316

High

1399230

LHX3
LIM/homeobox protein Lhx3

2

0

High-throughput

0.316

High

1399232

HSPB7
Heat shock protein beta-7

2

0

High-throughput

0.316

High

1399234

ZN835
Zinc finger protein 835

2

0

High-throughput

0.316

High

1399235

ATP23
Mitochondrial inner membrane protease ATP23 homolog

2

0

High-throughput

0.316

High

587189

ITF2
Transcription factor 4

1

0

High-throughput

0.299

High

1230213

K1C40
Keratin, type I cytoskeletal 40

1

0

High-throughput

0.299

High

190463

COPT1
High affinity copper uptake protein 1

1

0

High-throughput

0.279

Low

1181531

RA1L2
Heterogeneous nuclear ribonucleoprotein A1-like 2

1

0

High-throughput

0.279

Low

1292544

AMGO1
Amphoterin-induced protein 1

1

0

High-throughput

0.279

Low

1388922

MTMR8
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR8

1

0

High-throughput

0.279

Low

1399229

XPP1
Xaa-Pro aminopeptidase 1

1

0

High-throughput

0.279

Low

422928

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.261

Low

959519

YPEL3
Protein yippee-like 3

1

0

High-throughput

0.251

Low

861731

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

0

Small-scale

0.249

Low

1399233

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low

351244

MOT3
Monocarboxylate transporter 3

1

0

High-throughput

0.232

Low

470330

NEP
Neprilysin

1

0

Small-scale

0.232

Low

854574

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025