Protein: SMTN
Smoothelin

Gene: SMTN
Organism: Homo sapiens
Interactions: 51
UniProt ID: P53814

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton
GO:0006939 - smooth muscle contraction
GO:0007517 - muscle organ development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

923703

FIL1L
Filamin A-interacting protein 1-like

2

20

High-throughput

0.606

High

371552

MYC
Myc proto-oncogene protein

3

8

High-throughput

0.599

High

552932

PIP
Prolactin-inducible protein

2

0

High-throughput

0.576

High

923702

CF184
Cilia- and flagella-associated protein 184

2

1

High-throughput

0.549

High

549106

CDK4
Cyclin-dependent kinase 4

1

6

High-throughput

0.536

High

866928

CAPZB
F-actin-capping protein subunit beta

1

4

High-throughput

0.536

High

923701

KIF7
Kinesin-like protein KIF7

1

1

High-throughput

0.536

High

923713

TRI52
E3 ubiquitin-protein ligase TRIM52

1

7

High-throughput

0.536

High

923712

ESR2
Estrogen receptor beta

2

20

High-throughput

0.521

High

923705

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.513

High

923715

BRMS1
Breast cancer metastasis-suppressor 1

1

1

Small-scale

0.508

High

923690

GEM
GTP-binding protein GEM

1

5

High-throughput

0.489

High

923708

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

16

High-throughput

0.489

High

323254

TRI37
E3 ubiquitin-protein ligase TRIM37

1

17

High-throughput

0.479

High

329911

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

1

High-throughput

0.479

High

330784

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

385589

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

7

High-throughput

0.479

High

413466

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

629680

BTF3
Transcription factor BTF3

1

6

High-throughput

0.479

High

646796

PUR6
Bifunctional phosphoribosylaminoimidazole carboxylase/phosphoribosylaminoimidazole succinocarboxamide synthetase

1

2

High-throughput

0.479

High

713969

PML
Protein PML

1

10

High-throughput

0.479

High

798890

BRCA1
Breast cancer type 1 susceptibility protein

1

7

High-throughput

0.479

High

923692

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

3

Small-scale

0.479

High

923693

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.479

High

923694

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

923695

EWS
RNA-binding protein EWS

1

6

High-throughput

0.479

High

923698

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.479

High

620224

NUCL
Nucleolin

1

1

High-throughput

0.470

High

248853

GSDME
Gasdermin-E

1

2

High-throughput

0.445

High

374495

RASH
GTPase HRas

1

12

High-throughput

0.445

High

536816

HSP7C
Heat shock cognate 71 kDa protein

1

4

High-throughput

0.445

High

563470

CFTR
Cystic fibrosis transmembrane conductance regulator

1

8

High-throughput

0.445

High

923691

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

20

High-throughput

0.445

High

923696

BACD2
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2

1

20

High-throughput

0.445

High

923717

TRAK1
Trafficking kinesin-binding protein 1

1

20

High-throughput

0.445

High

923697

TNIP1
TNFAIP3-interacting protein 1

1

20

High-throughput

0.437

High

923699

RBBP5
Retinoblastoma-binding protein 5

1

10

High-throughput

0.437

High

923709

NUP43
Nucleoporin Nup43

1

11

High-throughput

0.437

High

923714

Q9H4D1
Receptor-interacting serine/threonine-protein kinase 4

1

20

High-throughput

0.437

High

923716

NLE1
Notchless protein homolog 1

1

7

High-throughput

0.437

High

923707

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

High-throughput

0.426

High

653715

PROZ
Vitamin K-dependent protein Z

1

2

High-throughput

0.407

High

923704

CF141
Uncharacterized protein C6orf141

1

1

High-throughput

0.407

High

923706

A16L1
Autophagy-related protein 16-1

1

11

High-throughput

0.407

High

923710

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

20

High-throughput

0.407

High

301377

WFS1
Wolframin

1

0

High-throughput

0.268

Low

378482

IL1A
Interleukin-1 alpha

1

0

Small-scale

0.249

Low

923711

ALG3
Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase

1

0

Small-scale

0.238

Low

50021

F170A
Protein FAM170A

1

0

High-throughput

0.232

Low

191311

P4HA2
Prolyl 4-hydroxylase subunit alpha-2

1

0

High-throughput

0.232

Low

923700

DOXA2
Dual oxidase maturation factor 2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025