Protein: CX6A1
Cytochrome c oxidase subunit 6A1, mitochondrial (Cytochrome c oxidase polypeptide VIa-liver) (Cytochrome c oxidase subunit VIA-liver) (COX VIa-L)

Gene: CX6A1, COX6A1
Organism: Homo sapiens
Interactions: 48
UniProt ID: P12074

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0006091 - generation of precursor metabolites and energy
GO:0006123 - mitochondrial electron transport, cytochrome c to oxygen
GO:0016491 - oxidoreductase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

551651

CX6B1
Cytochrome c oxidase subunit 6B1

2

1

High-throughput

0.789

High

360244

COX1
Cytochrome c oxidase subunit 1

1

2

High-throughput

0.691

High

360708

COX3
Cytochrome c oxidase subunit 3

1

1

High-throughput

0.691

High

528410

COX5B
Cytochrome c oxidase subunit 5B, mitochondrial

1

1

High-throughput

0.691

High

156184

CO72L
Cytochrome c oxidase subunit 7A2-like, mitochondrial

1

1

High-throughput

0.536

High

485829

COX6C
Cytochrome c oxidase subunit 6C

1

1

High-throughput

0.536

High

551649

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

2

High-throughput

0.536

High

551650

CX7A2
Cytochrome c oxidase subunit 7A2, mitochondrial

1

1

High-throughput

0.536

High

551652

QCR7
Cytochrome b-c1 complex subunit 7

1

1

High-throughput

0.536

High

551653

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

1

2

High-throughput

0.536

High

551666

COX42
Cytochrome c oxidase subunit 4 isoform 2, mitochondrial

1

2

High-throughput

0.536

High

168960

QCR8
Cytochrome b-c1 complex subunit 8

1

0

High-throughput

0.513

High

360367

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.513

High

551668

DHRS4
Dehydrogenase/reductase SDR family member 4

1

0

High-throughput

0.513

High

551664

CHC10
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial

1

1

High-throughput

0.479

High

551671

S2551
Mitochondrial nicotinamide adenine dinucleotide transporter SLC25A51

1

1

High-throughput

0.479

High

551674

CHCH2
Coiled-coil-helix-coiled-coil-helix domain-containing protein 2

1

1

High-throughput

0.479

High

50847

NDUF8
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 8

1

0

High-throughput

0.458

High

137632

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.458

High

143795

NDKM
Nucleoside diphosphate kinase, mitochondrial

1

0

High-throughput

0.458

High

164231

NRP1
Neuropilin-1

1

0

High-throughput

0.458

High

274968

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

283779

NDUS3
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial

1

0

High-throughput

0.458

High

292062

S2512
Electrogenic aspartate/glutamate antiporter SLC25A12, mitochondrial

1

0

High-throughput

0.458

High

505408

CISD3
CDGSH iron-sulfur domain-containing protein 3, mitochondrial

1

0

High-throughput

0.458

High

551658

SURF1
Surfeit locus protein 1

1

0

High-throughput

0.458

High

551659

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

Small-scale

0.458

High

551662

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.458

High

551670

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

551672

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.458

High

551673

OCAD1
OCIA domain-containing protein 1

1

0

High-throughput

0.458

High

528959

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

551667

LXN
Latexin

2

0

High-throughput

0.316

High

551654

HD
Huntingtin

2

0

High-throughput

0.306

High

395393

ESR1
Estrogen receptor

2

0

High-throughput

0.298

High

165892

FFAR1
Free fatty acid receptor 1

1

0

High-throughput

0.279

Low

269941

AUXI
Auxilin

1

0

High-throughput

0.279

Low

551660

MICB
MHC class I polypeptide-related sequence B

1

0

High-throughput

0.279

Low

551665

AQP3
Aquaporin-3

1

0

High-throughput

0.279

Low

551655

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.265

Low

551669

KLF16
Krueppel-like factor 16

1

0

High-throughput

0.261

Low

222672

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.249

Low

377382

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

551656

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

351200

MOT3
Monocarboxylate transporter 3

1

0

High-throughput

0.232

Low

551657

MFS10
Major facilitator superfamily domain-containing protein 10

1

0

High-throughput

0.232

Low

551661

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low

551663

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025