Protein: PP2BC
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (EC 3.1.3.16) (CAM-PRP catalytic subunit) (Calcineurin, testis-specific catalytic subunit) (Calmodulin-dependent calcineurin A subunit gamma isoform)

Gene: PP2BC, PPP3CC
Organism: Homo sapiens
Interactions: 69
UniProt ID: P48454

Gene Ontology (top 5):
GO:0004723 - calcium-dependent protein serine/threonine phosphatase activity
GO:0005516 - calmodulin binding
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

819143

CANB1
Calcineurin subunit B type 1

6

20

High-throughput

0.950

High

557526

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

3

13

High-throughput

0.861

High

819141

RCAN1
Calcipressin-1

4

11

High-throughput

0.699

High

819181

RCAN3
Calcipressin-3

4

11

High-throughput

0.699

High

819175

CANB2
Calcineurin subunit B type 2

1

20

High-throughput

0.691

High

317926

NFAC1
Nuclear factor of activated T-cells, cytoplasmic 1

3

10

High-throughput

0.667

High

505793

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

3

5

High-throughput

0.667

High

819138

GSK3A
Glycogen synthase kinase-3 alpha

3

18

High-throughput

0.667

High

819139

GSK3B
Glycogen synthase kinase-3 beta

3

19

High-throughput

0.667

High

819151

RCAN2
Calcipressin-2

3

11

High-throughput

0.667

High

819153

NFAC4
Nuclear factor of activated T-cells, cytoplasmic 4

3

11

High-throughput

0.667

High

819183

SIK3
Serine/threonine-protein kinase SIK3

3

12

High-throughput

0.667

High

819176

SPT33
Spermatogenesis-associated protein 33

3

2

High-throughput

0.665

High

819154

LRC41
Leucine-rich repeat-containing protein 41

3

0

High-throughput

0.638

High

819147

CDR2
Cerebellar degeneration-related protein 2

2

1

High-throughput

0.628

High

819155

RHG44
Rho GTPase-activating protein 44

2

4

High-throughput

0.628

High

819157

CRTC2
CREB-regulated transcription coactivator 2

2

11

High-throughput

0.628

High

819163

RHG22
Rho GTPase-activating protein 22

2

5

High-throughput

0.628

High

819167

SRBD1
S1 RNA-binding domain-containing protein 1

2

3

High-throughput

0.628

High

819168

PAR3L
Partitioning defective 3 homolog B

1

19

High-throughput

0.618

High

394318

A4
Amyloid-beta precursor protein

2

6

High-throughput

0.611

High

819149

U119A
Protein unc-119 homolog A

2

1

High-throughput

0.606

High

483985

CALM2
Calmodulin-2

1

15

High-throughput

0.575

High

484083

CALM3
Calmodulin-3

1

15

High-throughput

0.575

High

59741

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

2

High-throughput

0.574

High

623565

IBP6
Insulin-like growth factor-binding protein 6

2

2

High-throughput

0.574

High

819142

DEF1
Neutrophil defensin 1

2

2

High-throughput

0.574

High

819162

TAFA3
Chemokine-like protein TAFA-3

2

1

High-throughput

0.574

High

819164

T200A
Transmembrane protein 200A

2

2

High-throughput

0.574

High

819137

AMPH
Amphiphysin

1

7

High-throughput

0.573

High

369168

ESR1
Estrogen receptor

2

15

High-throughput

0.571

High

819165

ARI3B
AT-rich interactive domain-containing protein 3B

2

2

High-throughput

0.558

High

819145

PRR3
Proline-rich protein 3

1

2

High-throughput

0.536

High

819152

MAP7
Ensconsin

1

18

High-throughput

0.536

High

819158

LBH
Protein LBH

1

2

High-throughput

0.536

High

819159

KSR2
Kinase suppressor of Ras 2

1

16

High-throughput

0.536

High

819166

TENS4
Tensin-4

1

7

High-throughput

0.536

High

819179

THAP7
THAP domain-containing protein 7

1

0

High-throughput

0.518

High

819148

HGFA
Hepatocyte growth factor activator

1

0

High-throughput

0.513

High

819174

RITA1
RBPJ-interacting and tubulin-associated protein 1

1

0

High-throughput

0.513

High

819180

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.513

High

819184

AMMR1
Nuclear protein AMMECR1

1

0

High-throughput

0.513

High

489384

BCL2
Apoptosis regulator Bcl-2

1

14

Small-scale

0.501

High

396206

ARGI1
Arginase-1

1

0

High-throughput

0.493

High

472655

F163B
Protein FAM163B

1

2

High-throughput

0.489

High

819146

HXC5
Homeobox protein Hox-C5

1

1

High-throughput

0.489

High

819161

KCNKI
Potassium channel subfamily K member 18

1

2

High-throughput

0.489

High

819169

STAR8
StAR-related lipid transfer protein 8

1

6

High-throughput

0.489

High

819170

PMEPA
Protein TMEPAI

1

2

High-throughput

0.489

High

819173

CP074
Uncharacterized protein C16orf74

1

1

High-throughput

0.489

High

819144

CSK2B
Casein kinase II subunit beta

1

5

High-throughput

0.481

High

819172

IP3KC
Inositol-trisphosphate 3-kinase C

1

2

High-throughput

0.481

High

226815

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

455206

PARP1
Poly [ADP-ribose] polymerase 1

1

2

High-throughput

0.479

High

819140

PPT1
Palmitoyl-protein thioesterase 1

1

1

High-throughput

0.479

High

819156

Q4LE69
1-phosphatidylinositol 4-kinase

1

3

High-throughput

0.479

High

819160

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

819178

ATOH8
Transcription factor ATOH8

1

3

Small-scale

0.479

High

118232

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.460

High

787631

PI4KA
Phosphatidylinositol 4-kinase alpha

1

4

High-throughput

0.445

High

819150

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

18

High-throughput

0.445

High

776265

MLH1
DNA mismatch repair protein Mlh1

1

5

High-throughput

0.437

High

819177

CIC
Protein capicua homolog

1

11

High-throughput

0.437

High

409361

CASB
Beta-casein

2

0

High-throughput

0.328

High

819171

ESS2
Splicing factor ESS-2 homolog

2

0

High-throughput

0.328

High

263908

HYPM
Huntingtin-interacting protein M

1

0

High-throughput

0.279

Low

785680

ASIP
Agouti-signaling protein

1

0

High-throughput

0.279

Low

819182

TMCC3
Transmembrane and coiled-coil domain protein 3

1

0

High-throughput

0.279

Low

713068

SDC2
Syndecan-2

1

0

High-throughput

0.251

Low


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Last updated: 15 Jul 2024