Protein: PTPRJ
Receptor-type tyrosine-protein phosphatase eta (Protein-tyrosine phosphatase eta) (R-PTP-eta) (EC 3.1.3.48) (Density-enhanced phosphatase 1) (DEP-1) (HPTP eta) (Protein-tyrosine phosphatase receptor type J) (R-PTP-J) (CD antigen CD148)

Gene: PTPRJ
Organism: Homo sapiens
Interactions: 111
UniProt ID: Q12913

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001570 - vasculogenesis
GO:0001772 - immunological synapse
GO:0004725 - protein tyrosine phosphatase activity
GO:0005161 - platelet-derived growth factor receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1020090

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

3

18

Small-scale

0.849

High

441494

MET
Hepatocyte growth factor receptor

2

20

Small-scale

0.834

High

452405

PGFRB
Platelet-derived growth factor receptor beta

2

20

Small-scale

0.825

High

647561

MK03
Mitogen-activated protein kinase 3

2

14

Small-scale

0.819

High

338349

EGFR
Epidermal growth factor receptor

2

20

Small-scale

0.812

High

349275

RASH
GTPase HRas

2

17

High-throughput

0.793

High

572628

VGFR1
Vascular endothelial growth factor receptor 1

2

20

Small-scale

0.778

High

729647

VGFR2
Vascular endothelial growth factor receptor 2

1

19

Small-scale

0.761

High

350120

RASK
GTPase KRas

2

20

High-throughput

0.754

High

914038

RB11A
Ras-related protein Rab-11A

2

5

High-throughput

0.754

High

596398

RASA1
Ras GTPase-activating protein 1

1

13

High-throughput

0.698

High

972183

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

4

High-throughput

0.698

High

658916

MK01
Mitogen-activated protein kinase 1

1

14

Small-scale

0.667

High

119354

LEG9
Galectin-9

3

20

High-throughput

0.667

High

572351

LEG3
Galectin-3

3

20

High-throughput

0.667

High

239120

CTND1
Catenin delta-1

2

20

Small-scale

0.657

High

161362

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

9

High-throughput

0.647

High

182147

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

6

High-throughput

0.647

High

238402

JAK2
Tyrosine-protein kinase JAK2

1

20

High-throughput

0.647

High

383771

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

High-throughput

0.647

High

384743

NTRK1
High affinity nerve growth factor receptor

1

20

High-throughput

0.647

High

411369

INSR
Insulin receptor

1

20

High-throughput

0.647

High

411695

LCK
Tyrosine-protein kinase Lck

1

20

High-throughput

0.647

High

499261

KIT
Mast/stem cell growth factor receptor Kit

1

19

High-throughput

0.647

High

500961

GHR
Growth hormone receptor

1

19

High-throughput

0.647

High

580992

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

1

Small-scale

0.647

High

581162

EPOR
Erythropoietin receptor

1

20

High-throughput

0.647

High

610376

CBL
E3 ubiquitin-protein ligase CBL

1

6

High-throughput

0.647

High

725305

TIE1
Tyrosine-protein kinase receptor Tie-1

1

20

High-throughput

0.647

High

782783

CSK
Tyrosine-protein kinase CSK

1

20

High-throughput

0.647

High

788988

TEC
Tyrosine-protein kinase Tec

1

20

High-throughput

0.647

High

972322

TIE2
Angiopoietin-1 receptor

1

20

High-throughput

0.647

High

992570

ACK1
Activated CDC42 kinase 1

1

20

High-throughput

0.647

High

1020121

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.647

High

132838

SDCB1
Syntenin-1

1

10

Small-scale

0.621

High

120410

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

436276

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

545345

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564498

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

793291

MUC18
Cell surface glycoprotein MUC18

1

19

High-throughput

0.618

High

884479

RAB25
Ras-related protein Rab-25

1

5

High-throughput

0.618

High

892338

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

893944

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

900420

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

915635

RHOB
Rho-related GTP-binding protein RhoB

1

20

High-throughput

0.618

High

924529

GRB2
Growth factor receptor-bound protein 2

1

20

High-throughput

0.618

High

925235

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

950951

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1020096

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1020101

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1020108

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1020114

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1020115

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

717036

CTNB1
Catenin beta-1

2

20

Small-scale

0.611

High

121146

LEG8
Galectin-8

3

20

High-throughput

0.609

High

1020092

GAB1
GRB2-associated-binding protein 1

2

9

Small-scale

0.595

High

207443

LAT
Linker for activation of T-cells family member 1

1

1

Small-scale

0.569

High

310276

LYPD3
Ly6/PLAUR domain-containing protein 3

1

1

High-throughput

0.541

High

450860

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.541

High

1020095

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

1

12

High-throughput

0.541

High

1020098

SFRP4
Secreted frizzled-related protein 4

1

1

High-throughput

0.541

High

1020102

TEFF1
Tomoregulin-1

1

7

High-throughput

0.541

High

1020104

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

4

High-throughput

0.541

High

155899

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

6

High-throughput

0.536

High

449248

LEG1
Galectin-1

1

20

High-throughput

0.536

High

456379

CSF3
Granulocyte colony-stimulating factor

1

1

High-throughput

0.536

High

1020119

FBX2
F-box only protein 2

1

9

High-throughput

0.536

High

1020103

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.518

High

1020116

SIAS
Sialic acid synthase

1

0

High-throughput

0.518

High

580229

CADH2
Cadherin-2

1

20

High-throughput

0.501

High

790667

WASP
Actin nucleation-promoting factor WAS

1

9

High-throughput

0.501

High

803903

NSF
Vesicle-fusing ATPase

1

11

High-throughput

0.501

High

817318

LEPR
Leptin receptor

1

19

High-throughput

0.501

High

823378

PAXI
Paxillin

1

12

High-throughput

0.501

High

1020091

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

9

High-throughput

0.501

High

1020093

SQSTM
Sequestosome-1

1

3

Small-scale

0.501

High

1020106

CNKR1
Connector enhancer of kinase suppressor of ras 1

1

7

Small-scale

0.501

High

1020110

PKP4
Plakophilin-4

1

20

High-throughput

0.501

High

172854

CASC3
Protein CASC3

1

2

High-throughput

0.494

High

396521

CP17A
Steroid 17-alpha-hydroxylase/17,20 lyase

1

1

High-throughput

0.494

High

453068

HXC6
Homeobox protein Hox-C6

1

1

High-throughput

0.494

High

836301

KLK7
Kallikrein-7

1

10

High-throughput

0.494

High

915173

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

2

High-throughput

0.494

High

1020097

TSTD2
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

1

1

High-throughput

0.494

High

1020109

CANB2
Calcineurin subunit B type 2

1

1

High-throughput

0.494

High

1020111

TRMO
tRNA

1

1

High-throughput

0.494

High

1020112

HEMGN
Hemogen

1

1

High-throughput

0.494

High

1020113

PRD14
PR domain zinc finger protein 14

1

3

High-throughput

0.494

High

1020120

KLK9
Kallikrein-9

1

10

High-throughput

0.494

High

178507

STX7
Syntaxin-7

1

4

High-throughput

0.479

High

205341

TGON2
Trans-Golgi network integral membrane protein 2

1

6

High-throughput

0.479

High

227306

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.479

High

521898

CADH1
Cadherin-1

1

20

High-throughput

0.479

High

525923

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

542300

PLAK
Junction plakoglobin

1

20

Small-scale

0.479

High

814938

LEG7
Galectin-7

1

20

High-throughput

0.479

High

965654

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.479

High

923342

RL8
Large ribosomal subunit protein uL2

1

1

High-throughput

0.470

High

253556

CAPON
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein

1

8

High-throughput

0.437

High

1020099

RINT1
RAD50-interacting protein 1

1

1

High-throughput

0.437

High

1020100

RFIP1
Rab11 family-interacting protein 1

1

3

High-throughput

0.437

High

1020105

DDX17
Probable ATP-dependent RNA helicase DDX17

1

4

Small-scale

0.437

High

1020117

FBX6
F-box only protein 6

1

9

High-throughput

0.437

High

1020118

CS025
UPF0449 protein C19orf25

1

1

High-throughput

0.437

High

960684

FANCC
Fanconi anemia group C protein

1

0

High-throughput

0.282

High

1020094

BAAT
Bile acid-CoA:amino acid N-acyltransferase

1

0

High-throughput

0.282

High

1020107

ESIP1
Epithelial-stromal interaction protein 1

1

0

High-throughput

0.282

High

1020122

ZN510
Zinc finger protein 510

1

0

High-throughput

0.282

High

318478

CDS2
Phosphatidate cytidylyltransferase 2

1

0

High-throughput

0.279

Low

50342

CA226
Uncharacterized protein C1orf226

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024