Protein: APOD
Apolipoprotein D (Apo-D) (ApoD)

Gene: APOD
Organism: Homo sapiens
Interactions: 190
UniProt ID: P05090

Gene Ontology (top 5):
GO:0000302 - response to reactive oxygen species
GO:0001525 - angiogenesis
GO:0005319 - lipid transporter activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

423857

VAPA
Vesicle-associated membrane protein-associated protein A

4

1

High-throughput

0.700

High

230238

CREB3
Cyclic AMP-responsive element-binding protein 3

3

3

High-throughput

0.672

High

423839

RN126
E3 ubiquitin-protein ligase RNF126

3

1

High-throughput

0.667

High

160674

TOR1A
Torsin-1A

3

2

High-throughput

0.662

High

124196

HAX1
HCLS1-associated protein X-1

3

0

High-throughput

0.638

High

423806

SUMF2
Inactive C-alpha-formylglycine-generating enzyme 2

3

0

High-throughput

0.638

High

423820

RPE
Ribulose-phosphate 3-epimerase

3

0

High-throughput

0.638

High

423748

GPR3
G-protein coupled receptor 3

2

3

High-throughput

0.628

High

423767

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

2

1

High-throughput

0.628

High

423774

CD166
CD166 antigen

2

1

High-throughput

0.628

High

423779

ZIC1
Zinc finger protein ZIC 1

2

1

High-throughput

0.628

High

423814

NECT2
Nectin-2

2

1

High-throughput

0.628

High

166848

MGST3
Glutathione S-transferase 3, mitochondrial

2

1

High-throughput

0.606

High

423736

CD53
Leukocyte surface antigen CD53

2

1

High-throughput

0.606

High

423741

FPR2
N-formyl peptide receptor 2

2

3

High-throughput

0.606

High

423788

GORAB
RAB6-interacting golgin

2

1

High-throughput

0.606

High

423822

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

4

High-throughput

0.606

High

142044

CCN1
CCN family member 1

2

0

High-throughput

0.602

High

338675

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.602

High

423763

AT2B2
Plasma membrane calcium-transporting ATPase 2

2

0

High-throughput

0.602

High

423785

RNS13
Probable inactive ribonuclease-like protein 13

2

0

High-throughput

0.602

High

387500

APOA2
Apolipoprotein A-II

3

0

Small-scale

0.597

High

423769

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.580

High

423784

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.580

High

423786

F209A
Protein FAM209A

2

0

High-throughput

0.580

High

423823

APH1A
Gamma-secretase subunit APH-1A

2

0

High-throughput

0.580

High

423860

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

423866

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.580

High

423722

APOD
Apolipoprotein D

1

4

Small-scale

0.575

High

423795

RHG36
Rho GTPase-activating protein 36

2

3

High-throughput

0.574

High

65897

RHG42
Rho GTPase-activating protein 42

2

2

High-throughput

0.571

High

423760

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

0

Small-scale

0.559

High

423758

MAZ
Myc-associated zinc finger protein

2

1

High-throughput

0.558

High

423819

FUCT1
GDP-fucose transporter 1

2

1

High-throughput

0.558

High

423828

TSNA1
t-SNARE domain-containing protein 1

2

2

High-throughput

0.558

High

194669

FFAR2
Free fatty acid receptor 2

2

5

High-throughput

0.553

High

213674

AQP9
Aquaporin-9

2

2

High-throughput

0.553

High

292484

RHBL1
Rhomboid-related protein 1

2

2

High-throughput

0.553

High

423732

CD79A
B-cell antigen receptor complex-associated protein alpha chain

2

1

High-throughput

0.553

High

423747

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

3

High-throughput

0.553

High

423751

CXA8
Gap junction alpha-8 protein

2

1

High-throughput

0.553

High

423810

GP151
G-protein coupled receptor 151

2

3

High-throughput

0.553

High

423811

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.553

High

423852

S35C2
Solute carrier family 35 member C2

2

1

High-throughput

0.553

High

387204

APOA1
Apolipoprotein A-I

2

0

Small-scale

0.547

High

132551

UPK1A
Uroplakin-1a

1

3

High-throughput

0.536

High

276658

FKBP6
Inactive peptidyl-prolyl cis-trans isomerase FKBP6

1

2

High-throughput

0.536

High

352663

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

1

High-throughput

0.536

High

395314

ESR1
Estrogen receptor

1

2

High-throughput

0.536

High

423727

FGR
Tyrosine-protein kinase Fgr

1

1

High-throughput

0.536

High

423730

ARAF
Serine/threonine-protein kinase A-Raf

1

2

High-throughput

0.536

High

423731

PIM1
Serine/threonine-protein kinase pim-1

1

1

High-throughput

0.536

High

423734

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.536

High

423735

ATF6A
Cyclic AMP-dependent transcription factor ATF-6 alpha

1

5

High-throughput

0.536

High

423738

MAK
Serine/threonine-protein kinase MAK

1

1

High-throughput

0.536

High

423743

GLPK
Glycerol kinase

1

1

High-throughput

0.536

High

423752

PCP4
Calmodulin regulator protein PCP4

1

1

High-throughput

0.536

High

423755

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

1

High-throughput

0.536

High

423757

AAPK2
5'-AMP-activated protein kinase catalytic subunit alpha-2

1

1

High-throughput

0.536

High

423761

C1QT8
Complement C1q tumor necrosis factor-related protein 8

1

1

High-throughput

0.536

High

423765

APLP2
Amyloid beta precursor like protein 2

1

2

High-throughput

0.536

High

423813

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

1

High-throughput

0.536

High

423818

SIA7F
Alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

1

1

High-throughput

0.536

High

423824

SARAF
Store-operated calcium entry-associated regulatory factor

1

1

High-throughput

0.536

High

423835

MGST2
Microsomal glutathione S-transferase 2

1

1

High-throughput

0.536

High

423840

CDK19
Cyclin-dependent kinase 19

1

2

High-throughput

0.536

High

423867

STK24
Serine/threonine-protein kinase 24

1

3

High-throughput

0.515

High

123210

PDLI1
PDZ and LIM domain protein 1

1

0

High-throughput

0.513

High

170471

RAB7L
Ras-related protein Rab-7L1

1

0

High-throughput

0.513

High

248429

NMD3B
Glutamate receptor ionotropic, NMDA 3B

1

0

High-throughput

0.513

High

270877

CLAP2
CLIP-associating protein 2

1

0

High-throughput

0.513

High

303701

CYTF
Cystatin-F

1

0

High-throughput

0.513

High

351645

SG1D1
Secretoglobin family 1D member 1

1

0

High-throughput

0.513

High

423725

GDN
Glia-derived nexin

1

0

High-throughput

0.513

High

423726

HEXB
Beta-hexosaminidase subunit beta

1

0

High-throughput

0.513

High

423733

BMP4
Bone morphogenetic protein 4

1

0

High-throughput

0.513

High

423742

MK01
Mitogen-activated protein kinase 1

1

0

High-throughput

0.513

High

423749

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

0

High-throughput

0.513

High

423770

STX3
Syntaxin-3

1

0

High-throughput

0.513

High

423775

TFDP1
Transcription factor Dp-1

1

0

High-throughput

0.513

High

423812

MYO3B
Myosin-IIIb

1

0

High-throughput

0.513

High

423825

SCYL1
N-terminal kinase-like protein

1

0

High-throughput

0.513

High

423827

CFA57
Cilia- and flagella-associated protein 57

1

0

High-throughput

0.513

High

423832

MTMR9
Myotubularin-related protein 9

1

0

High-throughput

0.513

High

423836

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

1

0

High-throughput

0.513

High

423842

TX101
Testis-expressed protein 101

1

0

High-throughput

0.513

High

423849

PAAT
ATPase PAAT

1

0

High-throughput

0.513

High

423856

GPC5D
G-protein coupled receptor family C group 5 member D

1

0

High-throughput

0.513

High

117161

J9JIF5
CXXC-type zinc finger protein 4

1

0

High-throughput

0.493

High

423759

NAC3
Sodium/calcium exchanger 3

1

0

High-throughput

0.493

High

423817

CDS1
Phosphatidate cytidylyltransferase 1

1

0

High-throughput

0.493

High

423859

ZMYD8
MYND-type zinc finger-containing chromatin reader ZMYND8

1

0

High-throughput

0.493

High

282653

E2F6
Transcription factor E2F6

1

1

High-throughput

0.489

High

423739

CCNC
Cyclin-C

1

1

High-throughput

0.489

High

423753

PTSS1
Phosphatidylserine synthase 1

1

1

High-throughput

0.489

High

423762

CP4F8
Cytochrome P450 4F8

1

1

High-throughput

0.489

High

423766

GABPA
GA-binding protein alpha chain

1

2

High-throughput

0.489

High

423772

CUL2
Cullin-2

1

2

High-throughput

0.489

High

423803

CDK20
Cyclin-dependent kinase 20

1

1

High-throughput

0.489

High

423807

NFAM1
NFAT activation molecule 1

1

1

High-throughput

0.489

High

423831

TEFM
Transcription elongation factor, mitochondrial

1

1

High-throughput

0.489

High

423837

SH23A
SH2 domain-containing protein 3A

1

5

High-throughput

0.489

High

423851

SHCAF
SIN3-HDAC complex-associated factor

1

1

High-throughput

0.489

High

423853

ST7
Suppressor of tumorigenicity 7 protein

1

1

High-throughput

0.489

High

407777

SHBG
Sex hormone-binding globulin

1

2

Small-scale

0.481

High

423729

SAA2
Serum amyloid A-2 protein

1

1

High-throughput

0.479

High

423745

SAA4
Serum amyloid A-4 protein

1

1

High-throughput

0.479

High

423756

NEK2
Serine/threonine-protein kinase Nek2

1

1

Small-scale

0.479

High

423764

CREM
cAMP-responsive element modulator

1

3

Small-scale

0.479

High

423773

CUL4A
Cullin-4A

1

2

High-throughput

0.479

High

423833

RANB9
Ran-binding protein 9

1

1

Small-scale

0.479

High

69909

A8KA83
Vesicle-associated membrane protein-associated protein A

1

1

High-throughput

0.470

High

193386

GPR42
G-protein coupled receptor 42

1

5

High-throughput

0.470

High

385358

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.460

High

129955

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.458

High

352836

AGR2
Anterior gradient protein 2 homolog

1

0

Small-scale

0.458

High

387579

APOC1
Apolipoprotein C-I

1

0

High-throughput

0.458

High

387609

APOC2
Apolipoprotein C-II

1

0

High-throughput

0.458

High

387644

APOC3
Apolipoprotein C-III

1

0

High-throughput

0.458

High

423740

CDK2
Cyclin-dependent kinase 2

1

0

High-throughput

0.458

High

423746

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

423768

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

0

High-throughput

0.458

High

423724

JUN
Transcription factor Jun

1

4

High-throughput

0.445

High

423754

BCAM
Basal cell adhesion molecule

1

1

High-throughput

0.445

High

423777

RFTN1
Raftlin

1

1

High-throughput

0.445

High

105110

APRIO
Alternative prion protein

1

1

High-throughput

0.437

High

302315

RNF8
E3 ubiquitin-protein ligase RNF8

1

1

High-throughput

0.437

High

423815

ESR2
Estrogen receptor beta

1

2

High-throughput

0.437

High

423858

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

5

High-throughput

0.437

High

169292

LECT2
Leukocyte cell-derived chemotaxin-2

1

0

High-throughput

0.426

High

379187

IGHG1
Immunoglobulin heavy constant gamma 1

1

0

High-throughput

0.426

High

423723

7B2
Neuroendocrine protein 7B2

1

0

High-throughput

0.426

High

423737

RAB5A
Ras-related protein Rab-5A

1

0

High-throughput

0.426

High

423864

MOFA1
MORF4 family-associated protein 1

1

0

High-throughput

0.426

High

423865

SERC
Phosphoserine aminotransferase

1

0

High-throughput

0.426

High

423728

MYZAP
Myocardial zonula adherens protein

1

2

High-throughput

0.417

High

48187

A0AVG3
t-SNARE domain containing 1

1

2

High-throughput

0.407

High

423776

GLPK3
Glycerol kinase 3

1

1

High-throughput

0.407

High

423790

A16L1
Autophagy-related protein 16-1

1

1

High-throughput

0.407

High

423796

DPPA4
Developmental pluripotency-associated protein 4

3

0

High-throughput

0.347

High

176436

GRRE1
Granule associated Rac and RHOG effector protein 1

2

0

High-throughput

0.328

High

423794

DHX57
Putative ATP-dependent RNA helicase DHX57

2

0

High-throughput

0.328

High

423844

SPRTN
DNA-dependent metalloprotease SPRTN

2

0

High-throughput

0.318

High

186462

VA0E1
V-type proton ATPase subunit e 1

2

0

High-throughput

0.316

High

337855

CLD7
Claudin-7

2

0

High-throughput

0.316

High

423744

EVI2B
Protein EVI2B

2

0

High-throughput

0.316

High

423750

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.316

High

423771

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.316

High

423781

SOAT
Sodium-dependent organic anion transporter

2

0

High-throughput

0.316

High

423783

MTEF2
Transcription termination factor 2, mitochondrial

2

0

High-throughput

0.316

High

423792

CNDH2
Condensin-2 complex subunit H2

2

0

High-throughput

0.316

High

423799

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

423801

CLC10
C-type lectin domain family 10 member A

2

0

High-throughput

0.316

High

423804

TEX29
Testis-expressed protein 29

2

0

High-throughput

0.316

High

423805

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.316

High

423809

GDAP1
Ganglioside-induced differentiation-associated protein 1

2

0

High-throughput

0.316

High

423821

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

423829

TM237
Transmembrane protein 237

2

0

High-throughput

0.316

High

423834

VATO
V-type proton ATPase 21 kDa proteolipid subunit c''

2

0

High-throughput

0.316

High

423838

TMM79
Transmembrane protein 79

2

0

High-throughput

0.316

High

423841

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.316

High

423843

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

423846

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

423848

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

0

High-throughput

0.316

High

423855

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.316

High

423778

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

423782

TBRG1
Transforming growth factor beta regulator 1

1

0

High-throughput

0.279

Low

423789

RSBN1
Lysine-specific demethylase 9

1

0

High-throughput

0.279

Low

423793

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.279

Low

423797

DET1
DET1 homolog

1

0

High-throughput

0.279

Low

423798

AP2D
Transcription factor AP-2-delta

1

0

High-throughput

0.279

Low

423800

AROS
Active regulator of SIRT1

1

0

High-throughput

0.279

Low

423808

COQ8A
Atypical kinase COQ8A, mitochondrial

1

0

High-throughput

0.279

Low

423845

BRD8
Bromodomain-containing protein 8

1

0

High-throughput

0.279

Low

423854

MED17
Mediator of RNA polymerase II transcription subunit 17

1

0

High-throughput

0.279

Low

423863

ZN451
E3 SUMO-protein ligase ZNF451

1

0

High-throughput

0.279

Low

423826

FCRL1
Fc receptor-like protein 1

1

0

High-throughput

0.269

Low

423830

DEPD7
DEP domain-containing protein 7

1

0

High-throughput

0.269

Low

423787

TMM31
Transmembrane protein 31

1

0

High-throughput

0.251

Low

423791

GL1AD
DNA-directed RNA polymerase II subunit GRINL1A, isoforms 4/5

1

0

High-throughput

0.251

Low

423780

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

0

High-throughput

0.249

Low

423847

BACD3
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3

1

0

Small-scale

0.249

Low

165789

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

0

High-throughput

0.232

Low

213036

CP110
Centriolar coiled-coil protein of 110 kDa

1

0

High-throughput

0.232

Low

423802

SYT12
Synaptotagmin-12

1

0

High-throughput

0.232

Low

423816

NGN1
Neurogenin-1

1

0

High-throughput

0.232

Low

423850

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.232

Low

423861

LTOR2
Ragulator complex protein LAMTOR2

1

0

High-throughput

0.232

Low

423862

RT18C
Small ribosomal subunit protein bS18m

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025