Protein: PEX16
Peroxisomal membrane protein PEX16 (Peroxin-16) (Peroxisomal biogenesis factor 16)

Gene: PEX16
Organism: Homo sapiens
Interactions: 68
UniProt ID: Q9Y5Y5

Gene Ontology (top 5):
GO:0005777 - peroxisome
GO:0005778 - peroxisomal membrane
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

828478

PEX19
Peroxisomal biogenesis factor 19

12

0

Small-scale

0.727

High

941996

PEX3
Peroxisomal biogenesis factor 3

4

0

Small-scale

0.658

High

1452343

SCN3B
Sodium channel regulatory subunit beta-3

3

0

High-throughput

0.634

High

926874

VMAT1
Chromaffin granule amine transporter

2

1

High-throughput

0.606

High

1210332

MF14B
Hippocampus abundant transcript-like protein 1

2

2

High-throughput

0.606

High

60758

F234B
Protein FAM234B

2

0

High-throughput

0.602

High

1350623

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

2

0

High-throughput

0.602

High

1359165

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.602

High

181472

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.580

High

329681

LERL1
Leptin receptor overlapping transcript-like 1

2

0

High-throughput

0.580

High

1035498

TNR17
Tumor necrosis factor receptor superfamily member 17

2

0

High-throughput

0.580

High

1326961

EMC5
ER membrane protein complex subunit 5

2

0

High-throughput

0.580

High

1384387

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

2

0

High-throughput

0.580

High

1398534

ZDH15
Palmitoyltransferase ZDHHC15

2

0

High-throughput

0.580

High

1434970

REEP4
Receptor expression-enhancing protein 4

2

0

High-throughput

0.580

High

1490579

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

1491043

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.580

High

771274

APJ
Apelin receptor

2

2

High-throughput

0.574

High

1159126

C3AR
C3a anaphylatoxin chemotactic receptor

2

2

High-throughput

0.574

High

1197913

S39AC
Zinc transporter ZIP12

2

1

High-throughput

0.574

High

194766

FFAR2
Free fatty acid receptor 2

2

2

High-throughput

0.553

High

1134189

NTCP
Hepatic sodium/bile acid cotransporter

2

1

High-throughput

0.553

High

1186078

SOAT
Sodium-dependent organic anion transporter

2

1

High-throughput

0.553

High

1351732

GP152
Probable G-protein coupled receptor 152

2

3

High-throughput

0.553

High

1053092

VMAT2
Synaptic vesicular amine transporter

1

1

High-throughput

0.536

High

174165

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.513

High

818882

ADCY8
Adenylate cyclase type 8

1

0

High-throughput

0.513

High

1213736

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.513

High

1291318

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

0

High-throughput

0.513

High

1363263

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1391544

BSCL2
Seipin

1

0

High-throughput

0.513

High

1432463

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

719520

BKRB2
B2 bradykinin receptor

1

2

High-throughput

0.494

High

1386652

OPTN
Optineurin

1

0

High-throughput

0.493

High

832455

OPRX
Nociceptin receptor

1

1

High-throughput

0.489

High

867695

GPR12
G-protein coupled receptor 12

1

2

High-throughput

0.489

High

508913

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

0

High-throughput

0.480

High

279008

PEX14
Peroxisomal membrane protein PEX14

1

0

Small-scale

0.464

High

360154

NB5R3
NADH-cytochrome b5 reductase 3

1

0

High-throughput

0.460

High

1428528

ELOV4
Very long chain fatty acid elongase 4

1

0

High-throughput

0.460

High

1447923

SAR1A
Small COPII coat GTPase SAR1A

1

0

High-throughput

0.460

High

1491776

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

1

0

High-throughput

0.460

High

1214615

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

0

High-throughput

0.458

High

1366647

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

182858

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.445

High

1139611

S39AE
Metal cation symporter ZIP14

1

1

High-throughput

0.445

High

880890

NRAM2
Natural resistance-associated macrophage protein 2

1

0

High-throughput

0.426

High

1227794

A16L1
Autophagy-related protein 16-1

1

0

High-throughput

0.426

High

1366331

LPAR1
Lysophosphatidic acid receptor 1

1

2

High-throughput

0.407

High

549925

CD79A
B-cell antigen receptor complex-associated protein alpha chain

3

0

High-throughput

0.348

High

140042

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

2

0

High-throughput

0.316

High

336302

DEXI
Dexamethasone-induced protein

2

0

High-throughput

0.316

High

870091

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.316

High

1094882

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

1109104

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1307738

CLC10
C-type lectin domain family 10 member A

2

0

High-throughput

0.316

High

1447183

S35C2
Solute carrier family 35 member C2

2

0

High-throughput

0.316

High

848594

MAGA8
Melanoma-associated antigen 8

1

0

High-throughput

0.279

Low

880225

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.279

Low

1177216

MICB
MHC class I polypeptide-related sequence B

1

0

High-throughput

0.279

Low

718749

FCERG
High affinity immunoglobulin epsilon receptor subunit gamma

1

0

High-throughput

0.251

Low

1102473

BIK
Bcl-2-interacting killer

1

0

High-throughput

0.251

Low

1207659

F209A
Protein FAM209A

1

0

High-throughput

0.251

Low

1446604

TIDC1
Complex I assembly factor TIMMDC1, mitochondrial

1

0

High-throughput

0.251

Low

1005291

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1434358

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

869531

TNFL6
Tumor necrosis factor ligand superfamily member 6

1

0

High-throughput

0.232

Low

1310991

ZNT8
Proton-coupled zinc antiporter SLC30A8

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025