Protein: SGMR2
Sigma intracellular receptor 2 (S2R) (Sigma-2 receptor) (Sigma2 receptor) (Meningioma-associated protein 30) (MAC30) (Transmembrane protein 97)

Gene: SGMR2, TMEM97
Organism: Homo sapiens
Interactions: 108
UniProt ID: Q5BJF2

Gene Ontology (top 5):
GO:0001558 - regulation of cell growth
GO:0005764 - lysosome
GO:0005783 - endoplasmic reticulum
GO:0005791 - rough endoplasmic reticulum
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1142840

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.742

High

125748

STXB3
Syntaxin-binding protein 3

3

0

High-throughput

0.638

High

422257

A4
Amyloid-beta precursor protein

2

1

High-throughput

0.619

High

211921

SPIT1
Kunitz-type protease inhibitor 1

2

1

High-throughput

0.606

High

622058

CD53
Leukocyte surface antigen CD53

2

1

High-throughput

0.606

High

832626

AQP2
Aquaporin-2

2

2

High-throughput

0.606

High

850821

KI2L3
Killer cell immunoglobulin-like receptor 2DL3

2

1

High-throughput

0.606

High

1102793

UT1
Urea transporter 1

2

1

High-throughput

0.606

High

1155058

UT2
Urea transporter 2

2

1

High-throughput

0.606

High

1203118

GP152
Probable G-protein coupled receptor 152

2

1

High-throughput

0.606

High

1203122

LRC59
Leucine-rich repeat-containing protein 59

2

1

High-throughput

0.606

High

1203139

REEP1
Receptor expression-enhancing protein 1

2

1

High-throughput

0.606

High

1203145

RHCG
Ammonium transporter Rh type C

2

1

High-throughput

0.606

High

1106467

MADCA
Mucosal addressin cell adhesion molecule 1

2

0

High-throughput

0.602

High

380297

DRA
HLA class II histocompatibility antigen, DR alpha chain

2

0

High-throughput

0.585

High

194702

FFAR2
Free fatty acid receptor 2

2

0

High-throughput

0.580

High

258644

G37L1
G-protein coupled receptor 37-like 1

2

0

High-throughput

0.580

High

292648

RENR
Renin receptor

2

0

High-throughput

0.580

High

337741

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.580

High

337880

CLD7
Claudin-7

2

0

High-throughput

0.580

High

407099

HG2A
HLA class II histocompatibility antigen gamma chain

2

0

High-throughput

0.580

High

590293

MUC1
Mucin-1

2

0

High-throughput

0.580

High

800293

INGR2
Interferon gamma receptor 2

2

0

High-throughput

0.580

High

949251

MYPR
Myelin proteolipid protein

2

0

High-throughput

0.580

High

1132546

FXYD3
FXYD domain-containing ion transport regulator 3

2

0

High-throughput

0.580

High

1203114

DHB13
17-beta-hydroxysteroid dehydrogenase 13

2

0

High-throughput

0.580

High

1203115

CPLX4
Complexin-4

2

0

High-throughput

0.580

High

1203117

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.580

High

1203127

CGRF1
Cell growth regulator with RING finger domain protein 1

2

0

High-throughput

0.580

High

1203129

PD1L2
Programmed cell death 1 ligand 2

2

0

High-throughput

0.580

High

1203130

CSTN3
Calsyntenin-3

2

0

High-throughput

0.580

High

1203138

VISTA
V-type immunoglobulin domain-containing suppressor of T-cell activation

2

0

High-throughput

0.580

High

1203148

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.580

High

1203153

FKBP7
Peptidyl-prolyl cis-trans isomerase FKBP7

2

0

High-throughput

0.580

High

291726

CXB3
Gap junction beta-3 protein

2

2

High-throughput

0.553

High

335244

CXB5
Gap junction beta-5 protein

2

2

High-throughput

0.553

High

1108909

AQP6
Aquaporin-6

2

2

High-throughput

0.553

High

688700

NKG2D
NKG2-D type II integral membrane protein

1

0

High-throughput

0.513

High

732989

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

0

High-throughput

0.513

High

1203143

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.513

High

1203144

C5AR2
C5a anaphylatoxin chemotactic receptor 2

1

0

High-throughput

0.513

High

1203152

PCDGL
Protocadherin gamma-C4

1

0

High-throughput

0.513

High

870722

CXA8
Gap junction alpha-8 protein

1

2

High-throughput

0.481

High

363384

EGFR
Epidermal growth factor receptor

1

1

High-throughput

0.479

High

400942

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

2

High-throughput

0.479

High

562099

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

1027027

REEP5
Receptor expression-enhancing protein 5

1

1

High-throughput

0.479

High

1203147

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.479

High

549784

CD79A
B-cell antigen receptor complex-associated protein alpha chain

1

0

High-throughput

0.460

High

1134105

NTCP
Hepatic sodium/bile acid cotransporter

1

0

High-throughput

0.460

High

291364

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

375579

RASK
GTPase KRas

1

0

High-throughput

0.458

High

417477

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

0

High-throughput

0.458

High

820661

CEAM6
Cell adhesion molecule CEACAM6

1

0

High-throughput

0.458

High

947205

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.458

High

1024612

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1203126

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

948851

CD81
CD81 antigen

1

1

High-throughput

0.445

High

703947

DUS1
Dual specificity protein phosphatase 1

1

2

High-throughput

0.437

High

1163836

DUS6
Dual specificity protein phosphatase 6

1

2

High-throughput

0.437

High

1203128

DUS9
Dual specificity protein phosphatase 9

1

2

High-throughput

0.437

High

230188

S28A2
Sodium/nucleoside cotransporter 2

1

0

High-throughput

0.426

High

1203111

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1203146

NPCL1
NPC1-like intracellular cholesterol transporter 1

1

0

High-throughput

0.426

High

1162757

KGUA
Guanylate kinase

3

0

High-throughput

0.347

High

1203133

TM2D2
TM2 domain-containing protein 2

2

0

High-throughput

0.328

High

58666

FRMD3
FERM domain-containing protein 3

2

0

High-throughput

0.316

High

66931

AQ12B
Putative aquaporin-12B

2

0

High-throughput

0.316

High

71847

LEUTX
Paired-like homeodomain transcription factor LEUTX

2

0

High-throughput

0.316

High

155588

NEMP1
Nuclear envelope integral membrane protein 1

2

0

High-throughput

0.316

High

1094840

PDZ1I
PDZK1-interacting protein 1

2

0

High-throughput

0.316

High

1102398

BIK
Bcl-2-interacting killer

2

0

High-throughput

0.316

High

1187456

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1195224

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.316

High

1203110

F209A
Protein FAM209A

2

0

High-throughput

0.316

High

1203112

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.316

High

1203116

NDUF2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2

2

0

High-throughput

0.316

High

1203119

GPX8
Probable glutathione peroxidase 8

2

0

High-throughput

0.316

High

1203120

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

1203121

ASZ1
Ankyrin repeat, SAM and basic leucine zipper domain-containing protein 1

2

0

High-throughput

0.316

High

1203123

TM45B
Transmembrane protein 45B

2

0

High-throughput

0.316

High

1203124

RN170
E3 ubiquitin-protein ligase RNF170

2

0

High-throughput

0.316

High

1203131

TMM79
Transmembrane protein 79

2

0

High-throughput

0.316

High

1203132

T106C
Transmembrane protein 106C

2

0

High-throughput

0.316

High

1203134

B2L13
Bcl-2-like protein 13

2

0

High-throughput

0.316

High

1203135

MFF
Mitochondrial fission factor

2

0

High-throughput

0.316

High

1203136

IF3M
Translation initiation factor IF-3, mitochondrial

2

0

High-throughput

0.316

High

1203137

LIME1
Lck-interacting transmembrane adapter 1

2

0

High-throughput

0.316

High

1203141

SAR1A
Small COPII coat GTPase SAR1A

2

0

High-throughput

0.316

High

1203142

TM14B
Transmembrane protein 14B

2

0

High-throughput

0.316

High

1203149

TMX2
Thioredoxin-related transmembrane protein 2

2

0

High-throughput

0.316

High

1203150

CIA30
Complex I intermediate-associated protein 30, mitochondrial

2

0

High-throughput

0.316

High

173941

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.279

Low

1203125

NP1L5
Nucleosome assembly protein 1-like 5

1

0

High-throughput

0.279

Low

926776

VMAT1
Chromaffin granule amine transporter

1

0

High-throughput

0.251

Low

1203140

S35C2
Solute carrier family 35 member C2

1

0

High-throughput

0.251

Low

157458

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.249

Low

293792

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

588856

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

613069

EGR1
Early growth response protein 1

1

0

High-throughput

0.249

Low

695631

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768357

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

970614

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.249

Low

1004656

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1148343

KS6A1
Ribosomal protein S6 kinase alpha-1

1

0

High-throughput

0.249

Low

1162354

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low

1203113

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1203151

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025