Protein: TPST2
Protein-tyrosine sulfotransferase 2 (EC 2.8.2.20) (Tyrosylprotein sulfotransferase 2) (TPST-2)

Gene: TPST2
Organism: Homo sapiens
Interactions: 128
UniProt ID: O60704

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0005796 - Golgi lumen
GO:0005802 - trans-Golgi network

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

250918

TPST1
Protein-tyrosine sulfotransferase 1

2

0

High-throughput

0.736

High

253866

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

3

1

High-throughput

0.662

High

253815

ACHA3
Neuronal acetylcholine receptor subunit alpha-3

2

3

High-throughput

0.628

High

253909

S39A9
Zinc transporter ZIP9

2

3

High-throughput

0.628

High

253902

GOLP3
Golgi phosphoprotein 3

2

3

Small-scale

0.619

High

253850

S39A4
Zinc transporter ZIP4

3

3

High-throughput

0.609

High

253872

5HT3C
5-hydroxytryptamine receptor 3C

3

5

High-throughput

0.609

High

253887

SEC62
Translocation protein SEC62

2

0

High-throughput

0.576

High

253821

5HT3A
5-hydroxytryptamine receptor 3A

2

5

High-throughput

0.574

High

253832

ACHD
Acetylcholine receptor subunit delta

2

4

High-throughput

0.574

High

253901

GLP3L
Golgi phosphoprotein 3-like

1

3

Small-scale

0.561

High

253806

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

1

High-throughput

0.536

High

253808

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

2

High-throughput

0.536

High

253833

VAC14
Protein VAC14 homolog

1

1

High-throughput

0.536

High

253875

AT2A3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3

1

3

High-throughput

0.536

High

253892

TMM59
Transmembrane protein 59

1

1

High-throughput

0.536

High

253919

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

2

High-throughput

0.536

High

253799

USO1
General vesicular transport factor p115

1

0

High-throughput

0.513

High

253822

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

1

0

High-throughput

0.513

High

253837

TMED1
Transmembrane emp24 domain-containing protein 1

1

0

High-throughput

0.513

High

253842

TRAM1
Translocating chain-associated membrane protein 1

1

0

High-throughput

0.513

High

253849

PMF1
Polyamine-modulated factor 1

1

0

High-throughput

0.513

High

253858

DYM
Dymeclin

1

0

High-throughput

0.513

High

253869

CIP2A
Protein CIP2A

1

0

High-throughput

0.513

High

253874

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

0

High-throughput

0.513

High

253877

TBC20
TBC1 domain family member 20

1

0

High-throughput

0.513

High

253879

YIPF6
Protein YIPF6

1

0

High-throughput

0.513

High

253881

MRAP2
Melanocortin-2 receptor accessory protein 2

1

0

High-throughput

0.513

High

253888

RNF5
E3 ubiquitin-protein ligase RNF5

1

0

High-throughput

0.513

High

253890

ADPGK
ADP-dependent glucokinase

1

0

High-throughput

0.513

High

253897

MCLN1
Mucolipin-1

1

0

High-throughput

0.513

High

189076

IPO8
Importin-8

1

3

High-throughput

0.489

High

189337

STX7
Syntaxin-7

1

1

High-throughput

0.489

High

253800

SG2A1
Mammaglobin-B

1

2

High-throughput

0.489

High

253803

IPO7
Importin-7

1

3

High-throughput

0.489

High

253807

POTEI
POTE ankyrin domain family member I

1

1

High-throughput

0.489

High

253809

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

4

High-throughput

0.489

High

253810

AT2B1
Plasma membrane calcium-transporting ATPase 1

1

5

High-throughput

0.489

High

253812

AT2B4
Plasma membrane calcium-transporting ATPase 4

1

5

High-throughput

0.489

High

253813

NKG2A
NKG2-A/NKG2-B type II integral membrane protein

1

2

High-throughput

0.489

High

253814

CTR1
High affinity cationic amino acid transporter 1

1

6

High-throughput

0.489

High

253820

ACHA4
Neuronal acetylcholine receptor subunit alpha-4

1

3

High-throughput

0.489

High

253823

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.489

High

253825

CTR2
Cationic amino acid transporter 2

1

6

High-throughput

0.489

High

253827

AT12A
Potassium-transporting ATPase alpha chain 2

1

2

High-throughput

0.489

High

253828

XPO2
Exportin-2

1

3

High-throughput

0.489

High

253830

AT2B2
Plasma membrane calcium-transporting ATPase 2

1

3

High-throughput

0.489

High

253831

ACHE
Acetylcholine receptor subunit epsilon

1

4

High-throughput

0.489

High

253835

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

2

High-throughput

0.489

High

253836

SG2A2
Mammaglobin-A

1

2

High-throughput

0.489

High

253843

AT2B3
Plasma membrane calcium-transporting ATPase 3

1

4

High-throughput

0.489

High

253845

CL12B
C-type lectin domain family 12 member B

1

2

High-throughput

0.489

High

253870

IPO4
Importin-4

1

1

High-throughput

0.489

High

253871

CA054
Uncharacterized protein C1orf54

1

1

High-throughput

0.489

High

253873

CTR3
Cationic amino acid transporter 3

1

6

High-throughput

0.489

High

253885

IPO9
Importin-9

1

3

High-throughput

0.489

High

253895

XPO4
Exportin-4

1

1

High-throughput

0.489

High

253904

AT133
Polyamine-transporting ATPase 13A3

1

6

High-throughput

0.489

High

253906

AT131
Endoplasmic reticulum transmembrane helix translocase

1

4

High-throughput

0.489

High

253907

EI2BG
Translation initiation factor eIF2B subunit gamma

1

1

High-throughput

0.489

High

253911

KLHL9
Kelch-like protein 9

1

1

High-throughput

0.489

High

253912

KLH13
Kelch-like protein 13

1

1

High-throughput

0.489

High

253914

EI2BD
Translation initiation factor eIF2B subunit delta

1

2

High-throughput

0.489

High

253917

TNPO3
Transportin-3

1

2

High-throughput

0.489

High

217590

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

253839

SCRB2
Lysosome membrane protein 2

1

2

Small-scale

0.479

High

253853

ZNT10
Calcium/manganese antiporter SLC30A10

1

2

High-throughput

0.445

High

253824

CCR5
C-C chemokine receptor type 5

1

1

Small-scale

0.437

High

253840

SELPL
P-selectin glycoprotein ligand 1

1

1

Small-scale

0.437

High

253816

GPC1
Glypican-1 [Cleaved into: Secreted glypican-1]

1

0

High-throughput

0.426

High

253848

TM214
Transmembrane protein 214

1

0

High-throughput

0.426

High

253819

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

253841

S39AE
Metal cation symporter ZIP14

1

3

High-throughput

0.407

High

253868

S7A14
Solute carrier family 7 member 14

1

6

High-throughput

0.407

High

253918

5MP1
eIF5-mimic protein 1

1

1

High-throughput

0.407

High

253838

PTC1
Protein patched homolog 1

3

0

High-throughput

0.347

High

253882

TECT2
Tectonic-2

2

0

High-throughput

0.328

High

253860

HEAT3
HEAT repeat-containing protein 3

2

0

High-throughput

0.313

High

253880

SAAL1
Protein SAAL1

2

0

High-throughput

0.313

High

253891

RCAF1
GEL complex subunit OPTI

2

0

High-throughput

0.313

High

163867

NDC80
Kinetochore protein NDC80 homolog

1

0

High-throughput

0.279

Low

243870

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

0

High-throughput

0.279

Low

248810

GSDME
Gasdermin-E

1

0

High-throughput

0.279

Low

253801

DUS14
Dual specificity protein phosphatase 14

1

0

High-throughput

0.279

Low

253802

ZWINT
Outer kinetochore KNL1 complex subunit ZWINT

1

0

High-throughput

0.279

Low

253804

TOM40
Mitochondrial import receptor subunit TOM40 homolog

1

0

High-throughput

0.279

Low

253805

CYTS
Cystatin-S

1

0

High-throughput

0.279

Low

253811

NF1
Neurofibromin

1

0

High-throughput

0.279

Low

253817

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

253818

PEX19
Peroxisomal biogenesis factor 19

1

0

High-throughput

0.279

Low

253826

NUP98
Nuclear pore complex protein Nup98-Nup96

1

0

High-throughput

0.279

Low

253829

RAP1B
Ras-related protein Rap-1b

1

0

High-throughput

0.279

Low

253834

NU160
Nuclear pore complex protein Nup160

1

0

High-throughput

0.279

Low

253844

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

1

0

High-throughput

0.279

Low

253847

INT3
Integrator complex subunit 3

1

0

High-throughput

0.279

Low

253851

TMCO3
Transmembrane and coiled-coil domain-containing protein 3

1

0

High-throughput

0.279

Low

253854

THADA
tRNA

1

0

High-throughput

0.279

Low

253855

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.279

Low

253856

LARP4
La-related protein 4

1

0

High-throughput

0.279

Low

253857

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.279

Low

253859

SETX
Probable helicase senataxin

1

0

High-throughput

0.279

Low

253861

GP180
Integral membrane protein GPR180

1

0

High-throughput

0.279

Low

253864

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

253865

KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5

1

0

High-throughput

0.279

Low

253867

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.279

Low

253876

T106A
Transmembrane protein 106A

1

0

High-throughput

0.279

Low

253878

ERLEC
Endoplasmic reticulum lectin 1

1

0

High-throughput

0.279

Low

253883

TM169
Transmembrane protein 169

1

0

High-throughput

0.279

Low

253884

NSL1
Kinetochore-associated protein NSL1 homolog

1

0

High-throughput

0.279

Low

253886

XPO6
Exportin-6

1

0

High-throughput

0.279

Low

253889

CITE2
Cbp/p300-interacting transactivator 2

1

0

High-throughput

0.279

Low

253893

NUF2
Kinetochore protein Nuf2

1

0

High-throughput

0.279

Low

253894

ZY11B
Protein zyg-11 homolog B

1

0

High-throughput

0.279

Low

253896

TTYH3
Protein tweety homolog 3

1

0

High-throughput

0.279

Low

253898

MIS12
Protein MIS12 homolog

1

0

High-throughput

0.279

Low

253899

INT2
Integrator complex subunit 2

1

0

High-throughput

0.279

Low

253900

DSN1
Kinetochore-associated protein DSN1 homolog

1

0

High-throughput

0.279

Low

253903

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

253905

NOL11
Nucleolar protein 11

1

0

High-throughput

0.279

Low

253910

RMND1
Required for meiotic nuclear division protein 1 homolog

1

0

High-throughput

0.279

Low

253913

ATX10
Ataxin-10

1

0

High-throughput

0.279

Low

253915

PLAP
Phospholipase A-2-activating protein

1

0

High-throughput

0.279

Low

253916

NOC2L
Nucleolar complex protein 2 homolog

1

0

High-throughput

0.279

Low

253846

RHG29
Rho GTPase-activating protein 29

1

0

High-throughput

0.232

Low

253852

PXDC2
Plexin domain-containing protein 2

1

0

High-throughput

0.232

Low

253862

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

0

High-throughput

0.232

Low

253863

S35F2
Solute carrier family 35 member F2

1

0

High-throughput

0.232

Low

253908

F1142
Protein FAM114A2

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025