Protein: GLCE
D-glucuronyl C5-epimerase (EC 5.1.3.17) (Heparan sulfate C5-epimerase) (Hsepi) (Heparin/heparan sulfate:glucuronic acid C5-epimerase) (Heparosan-N-sulfate-glucuronate 5-epimerase)

Gene: GLCE
Organism: Homo sapiens
Interactions: 59
UniProt ID: O94923

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005509 - calcium ion binding
GO:0005794 - Golgi apparatus
GO:0008284 - positive regulation of cell population proliferation
GO:0015012 - heparan sulfate proteoglycan biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

322136

DEF5
Defensin alpha 5

2

0

High-throughput

0.602

High

322130

FGFR2
Fibroblast growth factor receptor 2

1

1

High-throughput

0.541

High

322131

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.541

High

322129

PGFRA
Platelet-derived growth factor receptor alpha

1

2

High-throughput

0.536

High

294804

BCAR3
Breast cancer anti-estrogen resistance protein 3

1

0

High-throughput

0.518

High

322124

ESR1
Estrogen receptor

1

0

High-throughput

0.518

High

322123

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.513

High

322144

HFE
Hereditary hemochromatosis protein

1

0

High-throughput

0.513

High

322163

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

322127

H10
Histone H1.0

1

0

High-throughput

0.493

High

322173

TNPO3
Transportin-3

1

1

High-throughput

0.489

High

217643

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

322165

KPCD2
Serine/threonine-protein kinase D2

1

0

High-throughput

0.458

High

322146

ZNT10
Calcium/manganese antiporter SLC30A10

1

3

High-throughput

0.445

High

322154

ZNT7
Zinc transporter 7

1

3

High-throughput

0.445

High

322155

ZNT5
Proton-coupled zinc antiporter SLC30A5

1

3

High-throughput

0.445

High

322174

ZNT1
Proton-coupled zinc antiporter SLC30A1

1

3

High-throughput

0.445

High

322158

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.426

High

322137

LAT1
Large neutral amino acids transporter small subunit 1

1

1

High-throughput

0.407

High

322170

LAT2
Large neutral amino acids transporter small subunit 2

1

1

High-throughput

0.407

High

322162

HAUS7
HAUS augmin-like complex subunit 7

4

0

High-throughput

0.360

High

322132

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.347

High

322168

GINM1
Glycoprotein integral membrane protein 1

3

0

High-throughput

0.347

High

322160

SAAL1
Protein SAAL1

2

0

High-throughput

0.313

High

322161

CK5P3
CDK5 regulatory subunit-associated protein 3

2

0

High-throughput

0.313

High

186178

PPM1D
Protein phosphatase 1D

1

0

High-throughput

0.282

High

322122

BAG4
BAG family molecular chaperone regulator 4

1

0

High-throughput

0.282

High

322125

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.282

High

322138

PAX2
Paired box protein Pax-2

1

0

High-throughput

0.282

High

322141

CASP8
Caspase-8

1

0

High-throughput

0.282

High

322156

RBCC1
RB1-inducible coiled-coil protein 1

1

0

High-throughput

0.282

High

164496

TNPO2
Transportin-2

1

0

High-throughput

0.279

Low

260818

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.279

Low

322128

CCL3
C-C motif chemokine 3

1

0

High-throughput

0.279

Low

322140

SG2A2
Mammaglobin-A

1

0

High-throughput

0.279

Low

322143

CL12B
C-type lectin domain family 12 member B

1

0

High-throughput

0.279

Low

322145

INT3
Integrator complex subunit 3

1

0

High-throughput

0.279

Low

322148

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.279

Low

322150

HEAT3
HEAT repeat-containing protein 3

1

0

High-throughput

0.279

Low

322151

HDBP1
Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1

1

0

High-throughput

0.279

Low

322152

SLF2
SMC5-SMC6 complex localization factor protein 2

1

0

High-throughput

0.279

Low

322153

KDM8
Bifunctional peptidase and arginyl-hydroxylase JMJD5

1

0

High-throughput

0.279

Low

322157

CA054
Uncharacterized protein C1orf54

1

0

High-throughput

0.279

Low

322164

TMPSD
Transmembrane protease serine 13

1

0

High-throughput

0.279

Low

322166

XPO4
Exportin-4

1

0

High-throughput

0.279

Low

322126

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

0

High-throughput

0.269

Low

322142

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

0

High-throughput

0.269

Low

322172

FBX7
F-box only protein 7

1

0

High-throughput

0.261

Low

322135

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.249

Low

322147

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

322171

TNIK
TRAF2 and NCK-interacting protein kinase

1

0

High-throughput

0.238

Low

322133

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.232

Low

322134

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.232

Low

322139

S13A2
Solute carrier family 13 member 2

1

0

High-throughput

0.232

Low

322149

NIPA1
Magnesium transporter NIPA1

1

0

High-throughput

0.232

Low

322159

SL9A6
Sodium/hydrogen exchanger 6

1

0

High-throughput

0.232

Low

322167

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.232

Low

322169

SCN3B
Sodium channel regulatory subunit beta-3

1

0

High-throughput

0.232

Low

322175

S4A7
Sodium bicarbonate cotransporter 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025