Protein: KKCC1
Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha)

Gene: KKCC1, CAMKK1
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q8N5S9

Gene Ontology (top 5):
GO:0004683 - calmodulin-dependent protein kinase activity
GO:0005516 - calmodulin binding
GO:0005524 - ATP binding
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

830421

KC1E
Casein kinase I isoform epsilon

1

16

High-throughput

0.691

High

1047947

KCC1A
Calcium/calmodulin-dependent protein kinase type 1

1

17

High-throughput

0.691

High

1049489

SAFB2
Scaffold attachment factor B2

1

3

High-throughput

0.691

High

1083219

KCC4
Calcium/calmodulin-dependent protein kinase type IV

1

11

High-throughput

0.691

High

1235193

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

1

20

High-throughput

0.691

High

982274

1433F
14-3-3 protein eta

3

19

Small-scale

0.681

High

1082282

DDB1
DNA damage-binding protein 1

1

0

High-throughput

0.656

High

1025174

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

19

Small-scale

0.647

High

231621

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.630

High

683541

1433B
14-3-3 protein beta/alpha

2

18

High-throughput

0.628

High

1235189

TRI11
E3 ubiquitin-protein ligase TRIM11

2

1

High-throughput

0.628

High

1235196

RUVB2
RuvB-like 2

2

2

High-throughput

0.628

High

1235197

RUVB1
RuvB-like 1

2

2

High-throughput

0.628

High

228049

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.618

High

432059

HS90A
Heat shock protein HSP 90-alpha

1

20

High-throughput

0.618

High

438353

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.618

High

624597

CCNE1
G1/S-specific cyclin-E1

1

4

High-throughput

0.618

High

1235195

UBQL2
Ubiquilin-2

1

6

High-throughput

0.618

High

647107

1433T
14-3-3 protein theta

2

18

Small-scale

0.611

High

909813

1433E
14-3-3 protein epsilon

2

9

High-throughput

0.611

High

166280

GRRE1
Granule associated Rac and RHOG effector protein 1

2

0

High-throughput

0.602

High

484024

CALM2
Calmodulin-2

1

19

High-throughput

0.575

High

484167

CALM3
Calmodulin-3

1

19

High-throughput

0.575

High

1235192

LPIN3
Phosphatidate phosphatase LPIN3

2

1

High-throughput

0.574

High

807442

RS10
Small ribosomal subunit protein eS10

1

1

High-throughput

0.536

High

904856

1433G
14-3-3 protein gamma

1

20

High-throughput

0.536

High

1234106

FBXL6
F-box/LRR-repeat protein 6

1

1

High-throughput

0.536

High

1235191

RNZ2
Zinc phosphodiesterase ELAC protein 2

1

1

High-throughput

0.536

High

281756

WFS1
Wolframin

1

1

High-throughput

0.515

High

388589

HSPB1
Heat shock protein beta-1

1

5

High-throughput

0.515

High

422236

NFL
Neurofilament light polypeptide

1

6

High-throughput

0.515

High

598228

FLNA
Filamin-A

1

4

High-throughput

0.515

High

742398

SYUA
Alpha-synuclein

1

2

High-throughput

0.515

High

791763

HD
Huntingtin

1

1

High-throughput

0.515

High

1231826

PIAS4
E3 SUMO-protein ligase PIAS4

1

2

High-throughput

0.515

High

1235190

PARK7
Parkinson disease protein 7

1

1

High-throughput

0.515

High

49661

IRGM
Immunity-related GTPase family M protein

1

0

High-throughput

0.513

High

234661

BRNP1
BMP/retinoic acid-inducible neural-specific protein 1

1

0

High-throughput

0.513

High

557396

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

944649

NTH
Endonuclease III-like protein 1

1

0

High-throughput

0.513

High

1028247

SBP1
Methanethiol oxidase

1

0

High-throughput

0.513

High

1164640

PADI6
Protein-arginine deiminase type-6

1

0

High-throughput

0.513

High

1235194

SF3B5
Splicing factor 3B subunit 5

1

0

High-throughput

0.513

High

395196

A4
Amyloid-beta precursor protein

1

3

High-throughput

0.501

High

336546

SODC
Superoxide dismutase [Cu-Zn]

1

0

High-throughput

0.493

High

893412

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

1044653

FHL3
Four and a half LIM domains protein 3

1

1

High-throughput

0.489

High

589217

ANXA7
Annexin A7

1

3

High-throughput

0.479

High

684209

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

952469

H33
Histone H3.3

1

2

High-throughput

0.479

High

1235198

RNF11
RING finger protein 11

1

3

High-throughput

0.470

High

529407

CFTR
Cystic fibrosis transmembrane conductance regulator

1

0

High-throughput

0.460

High

675840

GCH1
GTP cyclohydrolase 1

1

0

Small-scale

0.458

High

72999

B4DT77
Annexin

1

3

High-throughput

0.445

High

111562

K7EK07
Histone H3

1

2

High-throughput

0.445

High

315391

NSA2
Ribosome biogenesis protein NSA2 homolog

1

0

High-throughput

0.279

Low

495931

PPGB
Lysosomal protective protein

1

0

High-throughput

0.279

Low

1156961

NEPRO
Nucleolus and neural progenitor protein

1

0

High-throughput

0.279

Low

1223540

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024