Protein: ASGR2
Asialoglycoprotein receptor 2 (ASGP-R 2) (ASGPR 2) (C-type lectin domain family 4 member H2) (Hepatic lectin H2) (HL-2)

Gene: ASGR2
Organism: Homo sapiens
Interactions: 89
UniProt ID: P07307

Gene Ontology (top 5):
GO:0004873 - asialoglycoprotein receptor activity
GO:0005537 - D-mannose binding
GO:0005886 - plasma membrane
GO:0006897 - endocytosis
GO:0007166 - cell surface receptor signaling pathway

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

426826

NRG1
Pro-neuregulin-1, membrane-bound isoform

2

7

High-throughput

0.783

High

426840

CL17A
C-type lectin domain family 17, member A

2

16

High-throughput

0.783

High

426865

CLC7A
C-type lectin domain family 7 member A

2

15

High-throughput

0.783

High

426869

LMA2L
VIP36-like protein

3

3

High-throughput

0.667

High

426873

PARVG
Gamma-parvin

3

9

High-throughput

0.667

High

426868

TTYH3
Protein tweety homolog 3

3

0

High-throughput

0.638

High

426875

SERC1
Serine incorporator 1

3

0

High-throughput

0.638

High

426809

BIP
Endoplasmic reticulum chaperone BiP

2

7

High-throughput

0.628

High

426872

AGRL3
Adhesion G protein-coupled receptor L3

2

7

High-throughput

0.611

High

335644

COX1
Cytochrome c oxidase subunit 1

3

1

High-throughput

0.609

High

426815

SOAT1
Sterol O-acyltransferase 1

3

2

High-throughput

0.609

High

426837

TM214
Transmembrane protein 214

3

1

High-throughput

0.609

High

426850

MFSD8
Major facilitator superfamily domain-containing protein 8

3

2

High-throughput

0.609

High

131867

UPK2
Uroplakin-2

2

2

High-throughput

0.606

High

306750

VAMP5
Vesicle-associated membrane protein 5

2

3

High-throughput

0.606

High

364137

TFR1
Transferrin receptor protein 1

2

4

High-throughput

0.606

High

426811

CD53
Leukocyte surface antigen CD53

2

9

High-throughput

0.606

High

426812

PPLA
Cardiac phospholamban

2

1

High-throughput

0.606

High

426813

VATL
V-type proton ATPase 16 kDa proteolipid subunit c

2

3

High-throughput

0.606

High

426814

HMOX2
Heme oxygenase 2

2

2

High-throughput

0.606

High

426819

EMP1
Epithelial membrane protein 1

2

2

High-throughput

0.606

High

426824

PMP22
Peripheral myelin protein 22

2

3

High-throughput

0.606

High

426825

ILRL1
Interleukin-1 receptor-like 1

2

11

High-throughput

0.606

High

426836

TSPO2
Translocator protein 2

2

1

High-throughput

0.606

High

426845

MCEM1
Mast cell-expressed membrane protein 1

2

1

High-throughput

0.606

High

426881

VTI1B
Vesicle transport through interaction with t-SNAREs homolog 1B

2

3

High-throughput

0.606

High

426884

LCAP
Leucyl-cystinyl aminopeptidase

2

1

High-throughput

0.606

High

426885

STX8
Syntaxin-8

2

6

High-throughput

0.606

High

426828

Q08AM2
ADAM33 protein

1

14

High-throughput

0.594

High

426857

ERLEC
Endoplasmic reticulum lectin 1

2

5

Small-scale

0.584

High

207412

LAT
Linker for activation of T-cells family member 1

2

0

High-throughput

0.580

High

426822

S35A1
CMP-sialic acid transporter

2

0

High-throughput

0.580

High

426827

PLP2
Proteolipid protein 2

2

0

High-throughput

0.580

High

426834

M4A13
Membrane-spanning 4-domains subfamily A member 13

2

0

High-throughput

0.580

High

426846

PAQRA
Monocyte to macrophage differentiation factor 2

2

0

High-throughput

0.580

High

426879

AIG1
Androgen-induced gene 1 protein

2

0

High-throughput

0.580

High

426886

YIPF1
Protein YIPF1

2

0

High-throughput

0.580

High

426887

UBIA1
UbiA prenyltransferase domain-containing protein 1

2

0

High-throughput

0.580

High

426858

CERS2
Ceramide synthase 2

2

4

Small-scale

0.565

High

426852

GOGA5
Golgin subfamily A member 5

2

9

High-throughput

0.558

High

426853

LMBR1
Limb region 1 protein homolog

2

1

High-throughput

0.558

High

426877

ZDH18
Palmitoyltransferase ZDHHC18

2

1

High-throughput

0.558

High

426866

ADA33
Disintegrin and metalloproteinase domain-containing protein 33

1

12

High-throughput

0.555

High

169365

BET1
BET1 homolog

2

6

High-throughput

0.553

High

426832

ADIPO
Adiponectin

2

6

High-throughput

0.553

High

426847

TR1L1
Translocating chain-associated membrane protein 1-like 1

2

4

High-throughput

0.553

High

426851

S35B2
Adenosine 3'-phospho 5'-phosphosulfate transporter 1

2

1

High-throughput

0.553

High

426861

SC22A
Vesicle-trafficking protein SEC22a

2

7

High-throughput

0.553

High

426867

SMIM3
Small integral membrane protein 3

2

2

High-throughput

0.553

High

426876

RPRM
Protein reprimo

2

2

High-throughput

0.553

High

426878

TM140
Transmembrane protein 140

2

1

High-throughput

0.553

High

234767

ACSL4
Long-chain-fatty-acid--CoA ligase 4

1

2

High-throughput

0.536

High

426838

ZNT9
Proton-coupled zinc antiporter SLC30A9, mitochondrial

1

5

High-throughput

0.489

High

426817

GLP1R
Glucagon-like peptide 1 receptor

1

4

Small-scale

0.481

High

209594

PRC1
Protein regulator of cytokinesis 1

1

5

High-throughput

0.479

High

426844

SYVN1
E3 ubiquitin-protein ligase synoviolin

1

5

Small-scale

0.479

High

426854

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

4

Small-scale

0.479

High

426864

DERL1
Derlin-1

1

1

Small-scale

0.479

High

426874

FBX6
F-box only protein 6

1

3

Small-scale

0.479

High

426820

CD81
CD81 antigen

1

9

High-throughput

0.445

High

426842

MROH5
Maestro heat-like repeat family member 5

1

6

High-throughput

0.439

High

426863

VKOR1
Vitamin K epoxide reductase complex subunit 1

1

1

Small-scale

0.439

High

168493

SCAM2
Secretory carrier-associated membrane protein 2

1

1

High-throughput

0.437

High

426810

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

11

High-throughput

0.437

High

426823

EREP3
Protein ENTREP3

1

3

High-throughput

0.437

High

426830

OS9
Protein OS-9

1

5

Small-scale

0.437

High

426835

MANEA
Glycoprotein endo-alpha-1,2-mannosidase

1

1

High-throughput

0.437

High

426859

P121A
Nuclear envelope pore membrane protein POM 121

1

2

High-throughput

0.437

High

426882

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.437

High

426883

EGFL7
Epidermal growth factor-like protein 7

1

8

High-throughput

0.437

High

426841

TMPPE
Transmembrane protein with metallophosphoesterase domain

4

0

High-throughput

0.361

High

426816

TIMP3
Metalloproteinase inhibitor 3

3

0

High-throughput

0.347

High

426821

RL23
Large ribosomal subunit protein uL14

3

0

High-throughput

0.347

High

426849

S38A9
Neutral amino acid transporter 9

3

0

High-throughput

0.347

High

426862

JMJD8
JmjC domain-containing protein 8

3

0

High-throughput

0.347

High

426871

FKRP
Ribitol 5-phosphate transferase FKRP

3

0

High-throughput

0.347

High

426843

FA2H
Fatty acid 2-hydroxylase

2

0

High-throughput

0.316

High

426848

TM86B
Lysoplasmalogenase TMEM86B

2

0

High-throughput

0.316

High

426855

FATE1
Fetal and adult testis-expressed transcript protein

2

0

High-throughput

0.316

High

426870

TMM60
Transmembrane protein 60

2

0

High-throughput

0.316

High

426880

ORML1
ORM1-like protein 1

2

0

High-throughput

0.316

High

335027

DHE3
Glutamate dehydrogenase 1, mitochondrial

1

0

High-throughput

0.251

Low

426831

HES1
Transcription factor HES-1

1

0

High-throughput

0.251

Low

426818

IF1AX
Eukaryotic translation initiation factor 1A, X-chromosomal

1

0

High-throughput

0.249

Low

426829

SBP1
Methanethiol oxidase

1

0

High-throughput

0.249

Low

426833

AG10A
Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase

1

0

High-throughput

0.249

Low

426839

HACD2
Very-long-chain

1

0

High-throughput

0.249

Low

426856

RFT1
Man(5)GlcNAc(2)-PP-dolichol translocation protein RFT1

1

0

High-throughput

0.249

Low

426860

SENP5
Sentrin-specific protease 5

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024