Protein: CHD7
Chromodomain-helicase-DNA-binding protein 7 (CHD-7) (EC 3.6.4.12) (ATP-dependent helicase CHD7)

Gene: CHD7
Organism: Homo sapiens
Interactions: 143
UniProt ID: Q9P2D1

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001501 - skeletal system development
GO:0001701 - in utero embryonic development
GO:0001974 - blood vessel remodeling

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1336298

CHD8
Chromodomain-helicase-DNA-binding protein 8

2

15

Small-scale

0.843

High

847103

SMCA4
Transcription activator BRG1

2

19

Small-scale

0.789

High

918062

H4
Histone H4

2

13

High-throughput

0.754

High

935324

H31
Histone H3.1

2

20

High-throughput

0.754

High

1087449

H2B2E
Histone H2B type 2-E

1

20

High-throughput

0.691

High

818550

SOX2
Transcription factor SOX-2

4

20

Small-scale

0.686

High

455957

PARP1
Poly [ADP-ribose] polymerase 1

3

20

Small-scale

0.660

High

707773

H2B1B
Histone H2B type 1-B

1

20

High-throughput

0.618

High

828410

CENPA
Histone H3-like centromeric protein A

1

20

High-throughput

0.618

High

918744

H2B1C
Histone H2B type 1-C/E/F/G/I

1

20

High-throughput

0.618

High

952670

H33
Histone H3.3

1

20

High-throughput

0.618

High

1027300

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.618

High

1285377

PF21A
PHD finger protein 21A

1

20

High-throughput

0.618

High

1350239

ASH2L
Set1/Ash2 histone methyltransferase complex subunit ASH2

1

20

Small-scale

0.618

High

1251639

SMRC2
SWI/SNF complex subunit SMARCC2

2

20

Small-scale

0.611

High

1281258

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

2

20

Small-scale

0.611

High

348113

MYC
Myc proto-oncogene protein

2

20

High-throughput

0.584

High

487803

ANDR
Androgen receptor

2

20

Small-scale

0.584

High

123332

CBX4
E3 SUMO-protein ligase CBX4

1

20

High-throughput

0.575

High

370607

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

375013

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

10

High-throughput

0.571

High

801437

KI67
Proliferation marker protein Ki-67

1

10

High-throughput

0.536

High

821826

NEST
Nestin

1

20

High-throughput

0.536

High

997936

RBBP4
Histone-binding protein RBBP4

1

20

High-throughput

0.536

High

1039904

SNW1
SNW domain-containing protein 1

1

6

High-throughput

0.536

High

1069546

TEBP
Prostaglandin E synthase 3

1

1

High-throughput

0.536

High

1147487

ARID2
AT-rich interactive domain-containing protein 2

1

11

Small-scale

0.536

High

1199209

PB1
Protein polybromo-1

1

20

Small-scale

0.536

High

1272954

SMRC1
SWI/SNF complex subunit SMARCC1

1

20

Small-scale

0.536

High

1342808

BRD7
Bromodomain-containing protein 7

1

20

Small-scale

0.536

High

1350238

IKBL1
NF-kappa-B inhibitor-like protein 1

1

2

High-throughput

0.536

High

913811

RL7A
Large ribosomal subunit protein eL8

1

5

High-throughput

0.515

High

1332161

F124B
Protein FAM124B

1

1

Small-scale

0.515

High

1017249

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

6

Small-scale

0.500

High

1164516

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

1

11

Small-scale

0.500

High

1272993

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

11

Small-scale

0.500

High

1292502

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

1

11

Small-scale

0.500

High

1231757

AN36B
Ankyrin repeat domain-containing protein 36B

1

4

High-throughput

0.489

High

1306606

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.480

High

63975

DUXA
Double homeobox protein A

1

15

High-throughput

0.479

High

124109

SPT5H
Transcription elongation factor SPT5

1

8

High-throughput

0.479

High

146292

ARI1A
AT-rich interactive domain-containing protein 1A

1

15

High-throughput

0.479

High

171087

TBXT
T-box transcription factor T

1

12

High-throughput

0.479

High

179866

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

10

High-throughput

0.479

High

197844

CRX
Cone-rod homeobox protein

1

16

High-throughput

0.479

High

211986

TLX3
T-cell leukemia homeobox protein 3

1

14

High-throughput

0.479

High

213398

TLX2
T-cell leukemia homeobox protein 2

1

8

High-throughput

0.479

High

232559

KDM1A
Lysine-specific histone demethylase 1A

1

20

High-throughput

0.479

High

296157

MTA2
Metastasis-associated protein MTA2

1

20

High-throughput

0.479

High

317017

KLF8
Krueppel-like factor 8

1

18

High-throughput

0.479

High

377760

GCR
Glucocorticoid receptor

1

20

High-throughput

0.479

High

379973

MYCN
N-myc proto-oncogene protein

1

20

High-throughput

0.479

High

387646

P53
Cellular tumor antigen p53

1

8

High-throughput

0.479

High

415525

ATPB
ATP synthase subunit beta, mitochondrial

1

4

High-throughput

0.479

High

486837

MYB
Transcriptional activator Myb

1

12

High-throughput

0.479

High

505304

EGR2
E3 SUMO-protein ligase EGR2

1

4

High-throughput

0.479

High

507518

ERG
Transcriptional regulator ERG

1

12

High-throughput

0.479

High

524050

XRCC6
X-ray repair cross-complementing protein 6

1

8

High-throughput

0.479

High

570135

CEBPB
CCAAT/enhancer-binding protein beta

1

13

High-throughput

0.479

High

591128

BTF3
Transcription factor BTF3

1

2

High-throughput

0.479

High

620215

PAX7
Paired box protein Pax-7

1

15

High-throughput

0.479

High

620435

GATA2
Endothelial transcription factor GATA-2

1

17

High-throughput

0.479

High

620584

GATA3
Trans-acting T-cell-specific transcription factor GATA-3

1

17

High-throughput

0.479

High

632936

TYY1
Transcriptional repressor protein YY1

1

10

High-throughput

0.479

High

641583

PAX6
Paired box protein Pax-6

1

10

High-throughput

0.479

High

643923

SYVC
Valine--tRNA ligase

1

3

High-throughput

0.479

High

653017

APEX1
DNA repair nuclease/redox regulator APEX1

1

2

High-throughput

0.479

High

658570

TEAD1
Transcriptional enhancer factor TEF-1

1

4

High-throughput

0.479

High

679182

TLX1
T-cell leukemia homeobox protein 1

1

15

High-throughput

0.479

High

727603

HNF1B
Hepatocyte nuclear factor 1-beta

1

14

High-throughput

0.479

High

727814

SOX5
Transcription factor SOX-5

1

20

High-throughput

0.479

High

727934

SOX6
Transcription factor SOX-6

1

20

High-throughput

0.479

High

750509

COIL
Coilin

1

7

High-throughput

0.479

High

781237

ETV3
ETS translocation variant 3

1

13

High-throughput

0.479

High

782677

HNF4A
Hepatocyte nuclear factor 4-alpha

1

20

High-throughput

0.479

High

785417

ELK3
ETS domain-containing protein Elk-3

1

14

High-throughput

0.479

High

799024

GATA4
Transcription factor GATA-4

1

17

High-throughput

0.479

High

799152

NKX21
Homeobox protein Nkx-2.1

1

17

High-throughput

0.479

High

818841

SOX9
Transcription factor SOX-9

1

20

High-throughput

0.479

High

822688

LHX1
LIM/homeobox protein Lhx1

1

7

High-throughput

0.479

High

824479

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

18

High-throughput

0.479

High

831751

CEBPA
CCAAT/enhancer-binding protein alpha

1

13

High-throughput

0.479

High

839836

LHX2
LIM/homeobox protein Lhx2

1

6

High-throughput

0.479

High

878473

PAX9
Paired box protein Pax-9

1

9

High-throughput

0.479

High

881831

SOX10
Transcription factor SOX-10

1

20

Small-scale

0.479

High

923260

RL11
Large ribosomal subunit protein uL5

1

4

High-throughput

0.479

High

923573

RL8
Large ribosomal subunit protein uL2

1

2

High-throughput

0.479

High

959734

VIGLN
Vigilin

1

17

High-throughput

0.479

High

967993

PO5F1
POU domain, class 5, transcription factor 1

1

12

High-throughput

0.479

High

973888

PAX2
Paired box protein Pax-2

1

9

High-throughput

0.479

High

985263

HME1
Homeobox protein engrailed-1

1

1

High-throughput

0.479

High

987003

SUH
Recombining binding protein suppressor of hairless

1

10

High-throughput

0.479

High

988814

PAX8
Paired box protein Pax-8

1

11

High-throughput

0.479

High

1021365

FOXL1
Forkhead box protein L1

1

20

High-throughput

0.479

High

1031963

MTA1
Metastasis-associated protein MTA1

1

20

High-throughput

0.479

High

1035031

FKBP5
Peptidyl-prolyl cis-trans isomerase FKBP5

1

4

High-throughput

0.479

High

1063658

SUZ12
Polycomb protein SUZ12

1

9

High-throughput

0.479

High

1066808

KIF14
Kinesin-like protein KIF14

1

5

High-throughput

0.479

High

1070796

RBBP5
Retinoblastoma-binding protein 5

1

18

Small-scale

0.479

High

1071078

IRF4
Interferon regulatory factor 4

1

2

High-throughput

0.479

High

1075017

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.479

High

1080420

EZH2
Histone-lysine N-methyltransferase EZH2

1

20

High-throughput

0.479

High

1085191

TBR1
T-box brain protein 1

1

12

High-throughput

0.479

High

1116598

LARP7
La-related protein 7

1

19

High-throughput

0.479

High

1188971

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

9

High-throughput

0.479

High

1205826

P66A
Transcriptional repressor p66-alpha

1

13

High-throughput

0.479

High

1217352

VRK3
Serine/threonine-protein kinase VRK3

1

4

High-throughput

0.479

High

1221796

SMC5
Structural maintenance of chromosomes protein 5

1

12

High-throughput

0.479

High

1251358

OLIG1
Oligodendrocyte transcription factor 1

1

9

High-throughput

0.479

High

1254942

SP7
Transcription factor Sp7

1

12

High-throughput

0.479

High

1269810

ESR2
Estrogen receptor beta

1

20

High-throughput

0.479

High

1281194

LHX4
LIM/homeobox protein Lhx4

1

7

High-throughput

0.479

High

1300971

CIC
Protein capicua homolog

1

20

High-throughput

0.479

High

1304713

FEV
Protein FEV

1

11

High-throughput

0.479

High

1311936

SOX7
Transcription factor SOX-7

1

20

High-throughput

0.479

High

1315138

SALL3
Sal-like protein 3

1

9

High-throughput

0.479

High

1315379

KLF16
Krueppel-like factor 16

1

14

High-throughput

0.479

High

1326445

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

4

High-throughput

0.479

High

1332326

SOX17
Transcription factor SOX-17

1

20

High-throughput

0.479

High

1334036

WDR76
WD repeat-containing protein 76

1

20

High-throughput

0.479

High

1335865

ZBT20
Zinc finger and BTB domain-containing protein 20

1

6

High-throughput

0.479

High

1344512

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

13

High-throughput

0.479

High

1348357

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

5

High-throughput

0.479

High

1349418

VSX1
Visual system homeobox 1

1

12

High-throughput

0.479

High

1350240

LHX3
LIM/homeobox protein Lhx3

1

7

High-throughput

0.479

High

1350241

ZMYM2
Zinc finger MYM-type protein 2

1

4

High-throughput

0.479

High

1350242

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

1350243

RCOR1
REST corepressor 1

1

20

High-throughput

0.479

High

1350245

ASF1A
Histone chaperone ASF1A

1

7

High-throughput

0.479

High

1350246

ZN330
Zinc finger protein 330

1

5

High-throughput

0.479

High

1350247

KLF12
Krueppel-like factor 12

1

18

High-throughput

0.479

High

1350248

ETV7
Transcription factor ETV7

1

13

High-throughput

0.479

High

782961

GARS
Glycine--tRNA ligase

1

0

High-throughput

0.458

High

1350244

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.458

High

1199542

TLK2
Serine/threonine-protein kinase tousled-like 2

1

2

Small-scale

0.445

High

1334583

LN28A
Protein lin-28 homolog A

1

3

High-throughput

0.445

High

1349125

GRHL1
Grainyhead-like protein 1 homolog

1

3

High-throughput

0.445

High

806417

RL21
Large ribosomal subunit protein eL21

1

2

High-throughput

0.437

High

882617

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

3

High-throughput

0.437

High

1159459

FBX42
F-box only protein 42

1

4

High-throughput

0.437

High

831067

CTCF
Transcriptional repressor CTCF

1

5

Small-scale

0.408

High

856483

EFNA4
Ephrin-A4

1

0

High-throughput

0.249

Low

1256066

RHBL4
Rhomboid-related protein 4

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024