Protein: UNKL
Putative E3 ubiquitin-protein ligase UNKL (EC 2.3.2.-) (RING finger protein unkempt-like) (Zinc finger CCCH domain-containing protein 5-like)

Gene: UNKL
Organism: Homo sapiens
Interactions: 73
UniProt ID: Q9H9P5

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0008270 - zinc ion binding
GO:0016567 - protein ubiquitination
GO:0016740 - transferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

913050

HNRPF
Heterogeneous nuclear ribonucleoprotein F

2

19

High-throughput

0.783

High

1431503

CARD9
Caspase recruitment domain-containing protein 9

2

0

High-throughput

0.742

High

336780

BAG4
BAG family molecular chaperone regulator 4

3

3

High-throughput

0.654

High

1393317

SAHH3
Adenosylhomocysteinase 3

3

0

High-throughput

0.638

High

1329115

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

9

High-throughput

0.621

High

550471

PABP1
Polyadenylate-binding protein 1

1

11

High-throughput

0.618

High

1420666

UNK
RING finger protein unkempt homolog

1

7

High-throughput

0.618

High

682105

RBTN1
Rhombotin-1

2

1

High-throughput

0.615

High

180402

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

2

1

High-throughput

0.606

High

347938

BAG3
BAG family molecular chaperone regulator 3

2

3

High-throughput

0.606

High

505613

ATX1L
Ataxin-1-like

2

1

High-throughput

0.606

High

885421

HXA1
Homeobox protein Hox-A1

2

1

High-throughput

0.606

High

1271412

KCTD9
BTB/POZ domain-containing protein KCTD9

2

2

High-throughput

0.606

High

343707

GGPPS
Geranylgeranyl pyrophosphate synthase

2

0

High-throughput

0.602

High

1352895

TP4AP
Short transient receptor potential channel 4-associated protein

2

0

High-throughput

0.602

High

1372084

RBPMS
RNA-binding protein with multiple splicing

1

0

High-throughput

0.589

High

1194858

PPCEL
Prolyl endopeptidase-like

2

0

High-throughput

0.585

High

1039824

CREB5
Cyclic AMP-responsive element-binding protein 5

2

0

High-throughput

0.580

High

1392915

NTAQ1
Protein N-terminal glutamine amidohydrolase

2

0

High-throughput

0.580

High

988719

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

Small-scale

0.573

High

1394037

PP16A
Protein phosphatase 1 regulatory subunit 16A

2

5

High-throughput

0.553

High

1370753

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

0

Small-scale

0.549

High

1380856

TRI63
E3 ubiquitin-protein ligase TRIM63

1

6

High-throughput

0.541

High

1419297

TRI55
Tripartite motif-containing protein 55

1

8

High-throughput

0.541

High

156345

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

1

1

High-throughput

0.536

High

384552

CRYAA
Alpha-crystallin A chain

1

1

High-throughput

0.515

High

1289893

Q86V38
Atrophin 1

1

6

High-throughput

0.515

High

246960

KDM1A
Lysine-specific histone demethylase 1A

1

1

High-throughput

0.508

High

167651

GIPC1
PDZ domain-containing protein GIPC1

1

0

High-throughput

0.493

High

983344

RS28
Small ribosomal subunit protein eS28

1

1

High-throughput

0.481

High

1006724

SRPK2
SRSF protein kinase 2

1

7

High-throughput

0.481

High

1103384

CTBP1
C-terminal-binding protein 1

1

3

High-throughput

0.481

High

1137667

EXOS7
Exosome complex component RRP42

1

2

High-throughput

0.481

High

1146168

K1H1
Keratin, type I cuticular Ha1

1

5

High-throughput

0.481

High

1384025

EXOS8
Exosome complex component RRP43

1

2

High-throughput

0.481

High

1397920

DMRTB
Doublesex- and mab-3-related transcription factor B1

1

1

High-throughput

0.481

High

1400068

QKI
KH domain-containing RNA-binding protein QKI

1

7

High-throughput

0.481

High

162700

ANM5
Protein arginine N-methyltransferase 5

1

3

High-throughput

0.479

High

165416

PSA7
Proteasome subunit alpha type-7

1

3

High-throughput

0.479

High

535553

BIP
Endoplasmic reticulum chaperone BiP

1

5

High-throughput

0.479

High

633794

PSB1
Proteasome subunit beta type-1

1

7

High-throughput

0.479

High

681035

PSA1
Proteasome subunit alpha type-1

1

4

High-throughput

0.479

High

681519

PSA3
Proteasome subunit alpha type-3

1

5

High-throughput

0.479

High

681723

PSA4
Proteasome subunit alpha type-4

1

3

High-throughput

0.479

High

697662

PYR1
Multifunctional protein CAD

1

2

High-throughput

0.479

High

700739

PSA5
Proteasome subunit alpha type-5

1

3

High-throughput

0.479

High

701080

PSB6
Proteasome subunit beta type-6

1

5

High-throughput

0.479

High

701230

PSB5
Proteasome subunit beta type-5

1

3

High-throughput

0.479

High

755795

MCM4
DNA replication licensing factor MCM4

1

1

High-throughput

0.479

High

887594

PSB3
Proteasome subunit beta type-3

1

4

High-throughput

0.479

High

954913

PSA6
Proteasome subunit alpha type-6

1

4

High-throughput

0.479

High

1114331

CUL3
Cullin-3

1

5

High-throughput

0.479

High

1404411

CDC5L
Cell division cycle 5-like protein

1

5

High-throughput

0.479

High

1437186

HDC
Headcase protein homolog

1

2

High-throughput

0.479

High

1437189

PRP19
Pre-mRNA-processing factor 19

1

4

High-throughput

0.479

High

1308336

Q8IV28
Nidogen-2

1

1

High-throughput

0.470

High

1369702

KLK6
Kallikrein-6

1

3

High-throughput

0.470

High

1437183

ABC3C
DNA dC->dU-editing enzyme APOBEC-3C

1

0

High-throughput

0.460

High

298082

SPF27
Pre-mRNA-splicing factor SPF27

1

0

High-throughput

0.458

High

431611

AP2A
Transcription factor AP-2-alpha

1

1

High-throughput

0.457

High

1120553

NID2
Nidogen-2

1

1

High-throughput

0.439

High

1409946

DDX50
ATP-dependent RNA helicase DDX50

1

9

High-throughput

0.439

High

220304

FRS3
Fibroblast growth factor receptor substrate 3

2

0

High-throughput

0.316

High

654555

FBLN1
Fibulin-1

2

0

High-throughput

0.316

High

922369

CRBA2
Beta-crystallin A2

2

0

High-throughput

0.316

High

1279467

SAXO4
Stabilizer of axonemal microtubules 4

2

0

High-throughput

0.316

High

1399668

TGM7
Protein-glutamine gamma-glutamyltransferase Z

2

0

High-throughput

0.316

High

1437182

CABP2
Calcium-binding protein 2

2

0

High-throughput

0.316

High

1437188

RAB26
Ras-related protein Rab-26

2

0

High-throughput

0.316

High

1191403

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low

1437184

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

0

High-throughput

0.251

Low

1437185

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.251

Low

1437187

HOOK1
Protein Hook homolog 1

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025