Protein: MSLN
Mesothelin (CAK1 antigen) (Pre-pro-megakaryocyte-potentiating factor) [Cleaved into: Megakaryocyte-potentiating factor (MPF); Mesothelin, cleaved form]

Gene: MSLN
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q13421

Gene Ontology (top 5):
GO:0005576 - extracellular region
GO:0005788 - endoplasmic reticulum lumen
GO:0005794 - Golgi apparatus
GO:0005886 - plasma membrane
GO:0007155 - cell adhesion

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

168402

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.656

High

607366

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

0

High-throughput

0.656

High

1104559

DDX31
ATP-dependent DNA helicase DDX31

2

0

High-throughput

0.602

High

1104552

ZDH23
Palmitoyltransferase ZDHHC23

1

1

High-throughput

0.536

High

67430

GOG8A
Golgin subfamily A member 8A

1

0

High-throughput

0.513

High

332633

LYPD3
Ly6/PLAUR domain-containing protein 3

1

0

High-throughput

0.513

High

341302

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.513

High

342551

LY86
Lymphocyte antigen 86

1

0

High-throughput

0.513

High

377331

PAHO
Pancreatic polypeptide prohormone

1

0

High-throughput

0.513

High

548010

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

567848

PRG2
Bone marrow proteoglycan

1

0

High-throughput

0.513

High

880004

DNSL1
Deoxyribonuclease-1-like 1

1

0

High-throughput

0.513

High

1030158

IL5RA
Interleukin-5 receptor subunit alpha

1

0

High-throughput

0.513

High

1104547

GXLT1
Glucoside xylosyltransferase 1

1

0

High-throughput

0.513

High

1104548

BSPRY
B box and SPRY domain-containing protein

1

0

High-throughput

0.513

High

1104550

LYPD4
Ly6/PLAUR domain-containing protein 4

1

0

High-throughput

0.513

High

1104551

ZPBP2
Zona pellucida-binding protein 2

1

0

High-throughput

0.513

High

1104556

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

1104560

SDF2L
Stromal cell-derived factor 2-like protein 1

1

0

High-throughput

0.513

High

1104562

CBLN4
Cerebellin-4

1

0

High-throughput

0.513

High

1104563

FKB14
Peptidyl-prolyl cis-trans isomerase FKBP14

1

0

High-throughput

0.513

High

766088

PCGF2
Polycomb group RING finger protein 2

1

1

High-throughput

0.489

High

1055799

RING1
E3 ubiquitin-protein ligase RING1

1

1

High-throughput

0.489

High

218146

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

1104553

EMC5
ER membrane protein complex subunit 5

1

0

High-throughput

0.458

High

1104554

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

1104558

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1104555

APBP2
Amyloid protein-binding protein 2

2

0

High-throughput

0.316

High

1104557

CPLN2
Ciliogenesis and planar polarity effector 2

1

0

High-throughput

0.282

High

629838

BTF3
Transcription factor BTF3

1

0

High-throughput

0.279

Low

1104549

LAR1B
La-related protein 1B

1

0

High-throughput

0.279

Low

1104561

ANLN
Anillin

1

0

High-throughput

0.279

Low

1104546

EMC2
ER membrane protein complex subunit 2

1

0

High-throughput

0.249

Low

1104564

HDAC6
Protein deacetylase HDAC6

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025