Protein: ZDH23
Palmitoyltransferase ZDHHC23 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 23) (DHHC-23) (zDHHC23)

Gene: ZDH23, ZDHHC23
Organism: Homo sapiens
Interactions: 72
UniProt ID: Q8IYP9

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0005783 - endoplasmic reticulum
GO:0005794 - Golgi apparatus
GO:0006612 - protein targeting to membrane
GO:0018345 - protein palmitoylation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1315330

ZDH18
Palmitoyltransferase ZDHHC18

1

5

Small-scale

0.618

High

1315317

POF1B
Protein POF1B

2

1

High-throughput

0.574

High

1315313

GLIS1
Zinc finger protein GLIS1

2

3

High-throughput

0.553

High

63229

VP37C
Vacuolar protein sorting-associated protein 37C

1

1

High-throughput

0.536

High

299279

FLOT1
Flotillin-1

1

4

High-throughput

0.536

High

374743

RASH
GTPase HRas

1

20

High-throughput

0.536

High

463153

YES
Tyrosine-protein kinase Yes

1

8

High-throughput

0.536

High

463639

LYN
Tyrosine-protein kinase Lyn

1

7

High-throughput

0.536

High

603305

KPCA
Protein kinase C alpha type

1

2

High-throughput

0.536

High

893504

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

5

High-throughput

0.536

High

967217

RRAS2
Ras-related protein R-Ras2

1

20

High-throughput

0.536

High

1104552

MSLN
Mesothelin

1

1

High-throughput

0.536

High

1124852

FLOT2
Flotillin-2

1

4

High-throughput

0.536

High

1315321

VPP1
V-type proton ATPase 116 kDa subunit a 1

1

2

High-throughput

0.536

High

291674

XRP2
Protein XRP2

1

0

High-throughput

0.513

High

292459

PALM
Paralemmin-1

1

0

High-throughput

0.513

High

713170

NOS1
Nitric oxide synthase 1

1

2

Small-scale

0.512

High

422545

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.501

High

539889

RALB
Ras-related protein Ral-B

1

20

High-throughput

0.489

High

557373

SRC
Proto-oncogene tyrosine-protein kinase Src

1

7

High-throughput

0.489

High

659139

LORI
Loricrin

1

1

High-throughput

0.489

High

716038

GNA11
Guanine nucleotide-binding protein subunit alpha-11

1

5

High-throughput

0.489

High

893575

GBG10

1

1

High-throughput

0.489

High

1295334

CPNE8
Copine-8

1

2

High-throughput

0.489

High

1295482

MIB1
E3 ubiquitin-protein ligase MIB1

1

3

High-throughput

0.489

High

1315318

LMO7
LIM domain only protein 7

1

2

High-throughput

0.489

High

1315319

ASM3B
Acid sphingomyelinase-like phosphodiesterase 3b

1

1

High-throughput

0.489

High

1315322

CPNE2
Copine-2

1

2

High-throughput

0.489

High

1315328

ULBP3
UL16-binding protein 3

1

2

High-throughput

0.489

High

377650

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

1

Small-scale

0.479

High

414183

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

839313

MTOR
Serine/threonine-protein kinase mTOR

1

7

Small-scale

0.479

High

898246

R144A
E3 ubiquitin-protein ligase RNF144A

1

1

Small-scale

0.479

High

1111936

SNX1
Sorting nexin-1

1

5

Small-scale

0.479

High

132796

PK3CD
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform

1

8

Small-scale

0.437

High

255451

SNX2
Sorting nexin-2

1

5

Small-scale

0.437

High

261424

TBL1X
F-box-like/WD repeat-containing protein TBL1X

1

4

Small-scale

0.437

High

281761

VP26A
Vacuolar protein sorting-associated protein 26A

1

1

Small-scale

0.437

High

420283

IGF1
Insulin-like growth factor 1

1

1

Small-scale

0.437

High

439782

INSR
Insulin receptor

1

8

Small-scale

0.437

High

476751

RSSA
Small ribosomal subunit protein uS2

1

2

Small-scale

0.437

High

625833

RXRA
Retinoic acid receptor RXR-alpha

1

3

Small-scale

0.437

High

728327

AKT1
RAC-alpha serine/threonine-protein kinase

1

3

Small-scale

0.437

High

765696

BMI1
Polycomb complex protein BMI-1

1

8

Small-scale

0.437

High

772506

IRS1
Insulin receptor substrate 1

1

4

Small-scale

0.437

High

839048

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

8

Small-scale

0.437

High

973498

RS11
Small ribosomal subunit protein uS17

1

1

Small-scale

0.437

High

976753

ERF1
Eukaryotic peptide chain release factor subunit 1

1

1

Small-scale

0.437

High

982996

RS25
Small ribosomal subunit protein eS25

1

2

Small-scale

0.437

High

1055824

RING1
E3 ubiquitin-protein ligase RING1

1

8

Small-scale

0.437

High

1060618

PPARA
Peroxisome proliferator-activated receptor alpha

1

5

Small-scale

0.437

High

1153772

NCOA1
Nuclear receptor coactivator 1

1

1

Small-scale

0.437

High

1314821

ERF3B
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B

1

2

Small-scale

0.437

High

1315320

RENT1
Regulator of nonsense transcripts 1

1

2

Small-scale

0.437

High

1315323

VPS35
Vacuolar protein sorting-associated protein 35

1

2

Small-scale

0.437

High

1315324

SIN3A
Paired amphipathic helix protein Sin3a

1

1

Small-scale

0.437

High

1315325

RING2
E3 ubiquitin-protein ligase RING2

1

8

Small-scale

0.437

High

1315327

PCGF1
Polycomb group RING finger protein 1

1

8

Small-scale

0.437

High

1315332

SNX6
Sorting nexin-6

1

5

Small-scale

0.437

High

1315333

NCOR2
Nuclear receptor corepressor 2

1

1

Small-scale

0.437

High

156308

G3PT
Glyceraldehyde-3-phosphate dehydrogenase, testis-specific

2

0

High-throughput

0.328

High

749228

CD70
CD70 antigen

1

0

High-throughput

0.279

Low

1154323

CYTM
Cystatin-M

1

0

High-throughput

0.279

Low

1243093

ERIC5
Glutamate-rich protein 5

1

0

High-throughput

0.279

Low

1308634

AHNK2
Protein AHNAK2

1

0

High-throughput

0.279

Low

1309126

MISP
Mitotic interactor and substrate of PLK1

1

0

High-throughput

0.279

Low

1315314

CCNY
Cyclin-Y

1

0

High-throughput

0.279

Low

1315315

OCC1
Overexpressed in colon carcinoma 1 protein

1

0

High-throughput

0.279

Low

1315316

UBTD2
Ubiquitin domain-containing protein 2

1

0

High-throughput

0.279

Low

1315326

TS101
Tumor susceptibility gene 101 protein

1

0

High-throughput

0.279

Low

1315329

DEFM
Peptide deformylase, mitochondrial

1

0

High-throughput

0.279

Low

1315331

VPS28
Vacuolar protein sorting-associated protein 28 homolog

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025