Protein: BTBD8
BTB/POZ domain-containing protein 8 (AP2-interacting clathrin-endocytosis) (APache)

Gene: BTBD8
Organism: Homo sapiens
Interactions: 29
UniProt ID: Q5XKL5

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0016182 - synaptic vesicle budding from endosome
GO:0030122 - AP-2 adaptor complex
GO:0030424 - axon

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1113363

CUL3
Cullin-3

3

20

Small-scale

0.847

High

1220510

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

8

High-throughput

0.536

High

1162979

H2B2E
Histone H2B type 2-E

1

7

High-throughput

0.479

High

1220502

H2B1H
Histone H2B type 1-H

1

7

High-throughput

0.479

High

1220503

KIRR1
Kin of IRRE-like protein 1

1

11

High-throughput

0.470

High

957097

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

12

High-throughput

0.457

High

107392

F8W6N3
Ubiquitin carboxyl-terminal hydrolase

1

2

High-throughput

0.445

High

838736

MTREX
Exosome RNA helicase MTR4

1

7

High-throughput

0.445

High

1214630

RBM26
RNA-binding protein 26

1

6

High-throughput

0.445

High

1220499

TAF8
Transcription initiation factor TFIID subunit 8

1

1

High-throughput

0.445

High

1220504

LENG8
Leukocyte receptor cluster member 8

1

2

High-throughput

0.445

High

1220505

WDR26
WD repeat-containing protein 26

1

12

High-throughput

0.445

High

1220507

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

7

High-throughput

0.445

High

1220509

BAZ2A
Bromodomain adjacent to zinc finger domain protein 2A

1

16

High-throughput

0.445

High

326833

SPN1
Snurportin-1

1

0

High-throughput

0.438

High

1159295

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.426

High

1220498

ZC3HE
Zinc finger CCCH domain-containing protein 14

1

0

High-throughput

0.426

High

69688

A8K7Q2
Heat shock protein family A

1

15

High-throughput

0.407

High

116300

H3BPE1
Microtubule actin crosslinking factor 1

1

11

High-throughput

0.407

High

889290

NUMB
Protein numb homolog

1

8

High-throughput

0.407

High

1200453

COBL1
Cordon-bleu protein-like 1

1

9

High-throughput

0.407

High

1213052

RHG21
Rho GTPase-activating protein 21

1

10

High-throughput

0.407

High

1217407

OBSCN
Obscurin

1

13

High-throughput

0.407

High

1220501

AP3S1
AP-3 complex subunit sigma-1

1

1

High-throughput

0.407

High

1220508

B4GT7
Beta-1,4-galactosyltransferase 7

1

1

High-throughput

0.407

High

1220511

NUMBL
Numb-like protein

1

8

High-throughput

0.407

High

1122015

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.232

Low

1220500

LYSM2
LysM and putative peptidoglycan-binding domain-containing protein 2

1

0

High-throughput

0.232

Low

1220506

IMPCT
Protein IMPACT

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025