Protein: ANO6
Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F)

Gene: ANO6
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q4KMQ2

Gene Ontology (top 5):
GO:0002543 - activation of blood coagulation via clotting cascade
GO:0005227 - calcium-activated cation channel activity
GO:0005229 - intracellularly calcium-gated chloride channel activity
GO:0005244 - voltage-gated monoatomic ion channel activity
GO:0005247 - voltage-gated chloride channel activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1181199

ANO4
Anoctamin-4

2

3

High-throughput

0.776

High

127344

LEG8
Galectin-8

3

5

High-throughput

0.667

High

1195346

LEG9C
Galectin-9C

3

5

High-throughput

0.667

High

1010042

DLK1
Protein delta homolog 1

3

0

High-throughput

0.638

High

1155146

EREP1
Endosomal transmembrane epsin interactor 1

3

0

High-throughput

0.638

High

1195356

AGRG5
Adhesion G-protein coupled receptor G5

3

0

High-throughput

0.634

High

1195382

LMA2L
VIP36-like protein

3

0

High-throughput

0.634

High

718578

CDC27
Cell division cycle protein 27 homolog

2

3

High-throughput

0.628

High

1092971

CDC16
Cell division cycle protein 16 homolog

2

3

High-throughput

0.628

High

1195344

TGO1
Transport and Golgi organization protein 1 homolog

2

2

High-throughput

0.628

High

1195379

GPR21
Probable G-protein coupled receptor 21

2

2

High-throughput

0.628

High

1195400

CDC23
Cell division cycle protein 23 homolog

2

3

High-throughput

0.628

High

698720

CALX
Calnexin

2

1

High-throughput

0.611

High

1195404

CLC4E
C-type lectin domain family 4 member E

2

1

High-throughput

0.611

High

1195348

LRC8B
Volume-regulated anion channel subunit LRRC8B

2

0

High-throughput

0.602

High

1195354

OSTA
Organic solute transporter subunit alpha

2

0

High-throughput

0.602

High

1195361

LEMD2
LEM domain-containing protein 2

2

0

High-throughput

0.602

High

1195383

APC1
Anaphase-promoting complex subunit 1

2

0

High-throughput

0.602

High

1195401

APC5
Anaphase-promoting complex subunit 5

2

0

High-throughput

0.602

High

1195402

APC4
Anaphase-promoting complex subunit 4

2

0

High-throughput

0.602

High

125484

LEG9
Galectin-9

2

5

High-throughput

0.601

High

1195389

POPD2
Popeye domain-containing protein 2

2

0

High-throughput

0.585

High

375571

RASK
GTPase KRas

2

6

High-throughput

0.584

High

417471

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

1

High-throughput

0.584

High

951183

SC61B
Protein transport protein Sec61 subunit beta

2

2

High-throughput

0.584

High

978048

RHOB
Rho-related GTP-binding protein RhoB

2

7

High-throughput

0.584

High

1195403

FBX2
F-box only protein 2

2

0

High-throughput

0.576

High

1195365

ZNRF4
E3 ubiquitin-protein ligase ZNRF4

2

1

High-throughput

0.574

High

1195376

MIA2
Melanoma inhibitory activity protein 2

2

3

High-throughput

0.552

High

170788

CLGN
Calmegin

2

1

High-throughput

0.549

High

132601

UPK1A
Uroplakin-1a

1

1

High-throughput

0.536

High

248471

O10H2
Olfactory receptor 10H2

1

2

High-throughput

0.536

High

351900

S1PR4
Sphingosine 1-phosphate receptor 4

1

4

High-throughput

0.536

High

529913

TAU
Microtubule-associated protein tau

1

1

High-throughput

0.536

High

607934

ACHB2
Neuronal acetylcholine receptor subunit beta-2

1

2

High-throughput

0.536

High

723232

ACHB4
Neuronal acetylcholine receptor subunit beta-4

1

2

High-throughput

0.536

High

1185353

LEG9B
Galectin-9B

1

5

High-throughput

0.536

High

1195352

TMC4
Voltage-gated chloride channel TMC4

1

1

High-throughput

0.536

High

1195381

ACH10
Neuronal acetylcholine receptor subunit alpha-10

1

2

High-throughput

0.536

High

1195386

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.536

High

1195390

SEC12
Guanine nucleotide-exchange factor SEC12

1

1

High-throughput

0.536

High

1195407

O10H1
Olfactory receptor 10H1

1

2

High-throughput

0.536

High

164923

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

0

High-throughput

0.513

High

226330

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

592936

ANK1
Ankyrin-1

1

0

High-throughput

0.513

High

1060177

B2CL1
Bcl-2-like protein 1

1

0

High-throughput

0.513

High

1154632

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1195342

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.513

High

1195343

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1195351

SMIM5
Small integral membrane protein 5

1

0

High-throughput

0.513

High

1195359

SIDT2
SID1 transmembrane family member 2

1

0

High-throughput

0.513

High

1195362

CDC26
Anaphase-promoting complex subunit CDC26

1

0

High-throughput

0.513

High

1195363

TS1R2
Taste receptor type 1 member 2

1

0

High-throughput

0.513

High

1195391

KCMB3
Calcium-activated potassium channel subunit beta-3

1

0

High-throughput

0.513

High

1195364

RN133
E3 ubiquitin-protein ligase RNF133

1

1

High-throughput

0.489

High

1195398

MARH4
E3 ubiquitin-protein ligase MARCHF4

1

1

High-throughput

0.489

High

126629

RHOD
Rho-related GTP-binding protein RhoD

1

8

High-throughput

0.479

High

173938

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

2

High-throughput

0.479

High

188901

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.479

High

189600

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

218260

TGON2
Trans-Golgi network integral membrane protein 2

1

2

High-throughput

0.479

High

418176

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.479

High

466291

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

537273

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

562089

LAMP2
Lysosome-associated membrane glycoprotein 2

1

1

High-throughput

0.479

High

581087

RAC2
Ras-related C3 botulinum toxin substrate 2

1

5

High-throughput

0.479

High

604007

CXA1
Gap junction alpha-1 protein

1

1

High-throughput

0.479

High

612239

ARF4
ADP-ribosylation factor 4

1

2

High-throughput

0.479

High

630821

RAB4A
Ras-related protein Rab-4A

1

3

High-throughput

0.479

High

820657

CEAM6
Cell adhesion molecule CEACAM6

1

1

High-throughput

0.479

High

827198

ARL1
ADP-ribosylation factor-like protein 1

1

3

High-throughput

0.479

High

847549

SSRA
Translocon-associated protein subunit alpha

1

2

High-throughput

0.479

High

894785

EMD
Emerin

1

2

High-throughput

0.479

High

900845

RAB5C
Ras-related protein Rab-5C

1

3

High-throughput

0.479

High

901276

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

901846

RAB9A
Ras-related protein Rab-9A

1

4

High-throughput

0.479

High

903941

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

955243

CDC42
Cell division control protein 42 homolog

1

5

High-throughput

0.479

High

956321

RAB2A
Ras-related protein Rab-2A

1

3

High-throughput

0.479

High

962114

RHOA
Transforming protein RhoA

1

7

High-throughput

0.479

High

975066

ARF6
ADP-ribosylation factor 6

1

2

High-throughput

0.479

High

976304

RB11A
Ras-related protein Rab-11A

1

1

High-throughput

0.479

High

988412

RAC1
Ras-related C3 botulinum toxin substrate 1

1

5

High-throughput

0.479

High

1015486

RHOG
Rho-related GTP-binding protein RhoG

1

5

High-throughput

0.479

High

1087131

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

1144931

RAB35
Ras-related protein Rab-35

1

2

High-throughput

0.479

High

1163349

CAH9
Carbonic anhydrase 9

1

1

High-throughput

0.479

High

1195347

TECT3
Tectonic-3

1

2

High-throughput

0.479

High

1195353

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.479

High

1195357

CXD3
Gap junction delta-3 protein

1

1

High-throughput

0.479

High

1195360

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.479

High

1195366

CLC4D
C-type lectin domain family 4 member D

1

1

High-throughput

0.479

High

1195369

LRC59
Leucine-rich repeat-containing protein 59

1

1

High-throughput

0.479

High

1195373

DNJC1
DnaJ homolog subfamily C member 1

1

3

High-throughput

0.479

High

1195377

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

1195387

TMT1A
Thiol S-methyltransferase TMT1A

1

1

High-throughput

0.479

High

1195388

RHOF
Rho-related GTP-binding protein RhoF

1

8

High-throughput

0.479

High

1195392

SAR1A
Small COPII coat GTPase SAR1A

1

7

High-throughput

0.479

High

1195395

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

1195397

TM216
Transmembrane protein 216

1

1

High-throughput

0.479

High

1195399

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1195405

ALK
ALK tyrosine kinase receptor

1

1

High-throughput

0.479

High

1195406

LAMP3
Lysosome-associated membrane glycoprotein 3

1

1

High-throughput

0.479

High

1195408

SAR1B
Small COPII coat GTPase SAR1B

1

5

High-throughput

0.479

High

133751

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

0

High-throughput

0.458

High

580644

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

715612

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.458

High

845671

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.458

High

1058444

CKAP4
Cytoskeleton-associated protein 4

1

0

High-throughput

0.458

High

1195368

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.458

High

1195374

SNX27
Sorting nexin-27

1

0

High-throughput

0.458

High

1195380

DERL1
Derlin-1

1

0

High-throughput

0.458

High

1195393

PXMP2
Peroxisomal membrane protein 2

1

0

High-throughput

0.458

High

1195394

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

256043

S19A2
Thiamine transporter 1

1

1

High-throughput

0.445

High

609696

LEG3
Galectin-3

1

5

High-throughput

0.445

High

669324

ACKR3
Atypical chemokine receptor 3

1

2

High-throughput

0.445

High

704013

5HT1E
5-hydroxytryptamine receptor 1E

1

2

High-throughput

0.445

High

886061

CXCR3
C-X-C chemokine receptor type 3

1

3

High-throughput

0.445

High

956882

CXCR4
C-X-C chemokine receptor type 4

1

3

High-throughput

0.445

High

1052999

VMAT2
Synaptic vesicular amine transporter

1

1

High-throughput

0.445

High

1195367

LPAR1
Lysophosphatidic acid receptor 1

1

4

High-throughput

0.445

High

1195375

MF14A
Hippocampus abundant transcript 1 protein

1

3

High-throughput

0.445

High

1195378

S1PR3
Sphingosine 1-phosphate receptor 3

1

4

High-throughput

0.445

High

695618

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.437

High

1195350

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.437

High

1195371

TECT2
Tectonic-2

1

2

High-throughput

0.437

High

1195385

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

1

High-throughput

0.437

High

1195396

OTULL
Inactive ubiquitin thioesterase OTULINL

1

2

High-throughput

0.437

High

71212

HIDE1
Protein HIDE1

1

0

High-throughput

0.426

High

399579

VTNC
Vitronectin

1

0

High-throughput

0.426

High

835282

VIPR2
Vasoactive intestinal polypeptide receptor 2

1

0

High-throughput

0.426

High

868055

OR1D4
Olfactory receptor 1D4

1

0

High-throughput

0.426

High

948847

CD81
CD81 antigen

1

0

High-throughput

0.426

High

1195345

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

0

High-throughput

0.426

High

1195349

TMM88
Transmembrane protein 88

1

0

High-throughput

0.426

High

1195372

TM169
Transmembrane protein 169

1

0

High-throughput

0.426

High

1126296

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

2

0

High-throughput

0.313

High

1195358

KTAP2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit KCP2

1

0

High-throughput

0.279

Low

293781

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

887431

CEBPD
CCAAT/enhancer-binding protein delta

1

0

Small-scale

0.249

Low

1195355

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

1195384

DJC25
DnaJ homolog subfamily C member 25

1

0

High-throughput

0.249

Low

1195370

BSCL2
Seipin

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025