Protein: TM2D3
TM2 domain-containing protein 3 (Beta-amyloid-binding protein-like protein 2) (BBP-like protein 2)

Gene: TM2D3
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q9BRN9

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0045747 - positive regulation of Notch signaling pathway
GO:0046331 - lateral inhibition

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1390939

TSN17
Tetraspanin-17

3

0

High-throughput

0.638

High

1243381

LRC8B
Volume-regulated anion channel subunit LRRC8B

2

1

High-throughput

0.628

High

1029439

IL9R
Interleukin-9 receptor

2

1

High-throughput

0.611

High

378176

TNFA
Tumor necrosis factor

2

0

High-throughput

0.585

High

460278

CD3E
T-cell surface glycoprotein CD3 epsilon chain

2

0

High-throughput

0.585

High

1036243

NRG1
Pro-neuregulin-1, membrane-bound isoform

2

0

High-throughput

0.585

High

1249587

BTNL8
Butyrophilin-like protein 8

2

0

High-throughput

0.585

High

1411473

TM2D2
TM2 domain-containing protein 2

2

1

High-throughput

0.574

High

1203338

TM128
Transmembrane protein 128

2

1

High-throughput

0.558

High

1411493

SPCS1
Signal peptidase complex subunit 1

2

1

High-throughput

0.558

High

211944

SPIT1
Kunitz-type protease inhibitor 1

1

2

High-throughput

0.536

High

648645

FGFR4
Fibroblast growth factor receptor 4

1

1

High-throughput

0.536

High

650381

FGFR3
Fibroblast growth factor receptor 3

1

1

High-throughput

0.536

High

1237962

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

1

High-throughput

0.536

High

1411474

TM2D1
TM2 domain-containing protein 1

1

1

High-throughput

0.536

High

354168

CLPT1
Putative lipid scramblase CLPTM1

1

0

High-throughput

0.513

High

876722

HSP13
Heat shock 70 kDa protein 13

1

0

High-throughput

0.513

High

880193

PTH2R
Parathyroid hormone 2 receptor

1

0

High-throughput

0.513

High

941370

CAV3
Caveolin-3

1

0

High-throughput

0.513

High

1105768

ADAM9
Disintegrin and metalloproteinase domain-containing protein 9

1

0

High-throughput

0.513

High

1128942

I13R2
Interleukin-13 receptor subunit alpha-2

1

0

High-throughput

0.513

High

1143781

PON2
Serum paraoxonase/arylesterase 2

1

0

High-throughput

0.513

High

1153314

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.513

High

1212687

GT253
Inactive glycosyltransferase 25 family member 3

1

0

High-throughput

0.513

High

1248234

CSPG4
Chondroitin sulfate proteoglycan 4

1

0

High-throughput

0.513

High

1336107

KREM2
Kremen protein 2

1

0

High-throughput

0.513

High

1350594

GTR12
Solute carrier family 2, facilitated glucose transporter member 12

1

0

High-throughput

0.513

High

1382878

TTC17
Tetratricopeptide repeat protein 17

1

0

High-throughput

0.513

High

1411489

TM11E
Transmembrane protease serine 11E

1

0

High-throughput

0.513

High

1411490

ICAM5
Intercellular adhesion molecule 5

1

0

High-throughput

0.513

High

407885

SEMG1
Semenogelin-1

1

1

High-throughput

0.489

High

1036588

SEMG2
Semenogelin-2

1

1

High-throughput

0.489

High

1295795

C1QL4
Complement C1q-like protein 4

1

1

High-throughput

0.489

High

1398782

MBOA7
Membrane-bound acylglycerophosphatidylinositol O-acyltransferase MBOAT7

1

1

High-throughput

0.489

High

1411487

ERRFI
ERBB receptor feedback inhibitor 1

1

0

Small-scale

0.460

High

218692

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

774585

BASI
Basigin

1

0

High-throughput

0.458

High

256128

S19A2
Thiamine transporter 1

1

1

High-throughput

0.445

High

835006

S19A1
Reduced folate transporter

1

1

High-throughput

0.445

High

1236292

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

1411481

ANKH
Mineralization regulator ANKH

1

0

High-throughput

0.426

High

85149

B7Z3K1
cDNA FLJ51973

1

1

High-throughput

0.407

High

388794

C1QC
Complement C1q subcomponent subunit C

1

1

High-throughput

0.407

High

1402080

PCX1
Pecanex-like protein 1

1

3

High-throughput

0.407

High

1136157

SPCS2
Signal peptidase complex subunit 2

3

0

High-throughput

0.347

High

1288099

OAF
Out at first protein homolog

3

0

High-throughput

0.347

High

350624

TXD12
Thioredoxin domain-containing protein 12

3

0

High-throughput

0.345

High

123173

DX39A
ATP-dependent RNA helicase DDX39A

2

0

High-throughput

0.318

High

324033

CSTN1
Calsyntenin-1

2

0

High-throughput

0.318

High

665137

COT2
COUP transcription factor 2

2

0

High-throughput

0.318

High

1411472

CQ080
Mitochondrial nucleoid-associated protein 1

2

0

High-throughput

0.318

High

1411480

SACA1
Sperm acrosome membrane-associated protein 1

2

0

High-throughput

0.318

High

1411485

MTFP1
Mitochondrial fission process protein 1

2

0

High-throughput

0.318

High

1395281

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.282

High

343638

OXSR1
Serine/threonine-protein kinase OSR1

1

0

High-throughput

0.279

Low

350735

NOE2
Noelin-2

1

0

High-throughput

0.279

Low

460926

LDHC
L-lactate dehydrogenase C chain

1

0

High-throughput

0.279

Low

699048

CALX
Calnexin

1

0

High-throughput

0.279

Low

994951

SC11A
Signal peptidase complex catalytic subunit SEC11A

1

0

High-throughput

0.279

Low

1087077

FSTL1
Follistatin-related protein 1

1

0

High-throughput

0.279

Low

1143665

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.279

Low

1154255

NPTX1
Neuronal pentraxin-1

1

0

High-throughput

0.279

Low

1191953

TBB8
Tubulin beta-8 chain

1

0

High-throughput

0.279

Low

1204895

MKS3
Meckelin

1

0

High-throughput

0.279

Low

1213817

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

1225410

METRL
Meteorin-like protein

1

0

High-throughput

0.279

Low

1228400

SE1L3
Protein sel-1 homolog 3

1

0

High-throughput

0.279

Low

1247512

POTEE
POTE ankyrin domain family member E

1

0

High-throughput

0.279

Low

1249683

IGFL3
Insulin growth factor-like family member 3

1

0

High-throughput

0.279

Low

1275404

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

0

High-throughput

0.279

Low

1278360

COMD6
COMM domain-containing protein 6

1

0

High-throughput

0.279

Low

1333839

TTC13
Tetratricopeptide repeat protein 13

1

0

High-throughput

0.279

Low

1334405

UXS1
UDP-glucuronic acid decarboxylase 1

1

0

High-throughput

0.279

Low

1352508

GPX8
Probable glutathione peroxidase 8

1

0

High-throughput

0.279

Low

1357939

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.279

Low

1384219

LDAF1
Lipid droplet assembly factor 1

1

0

High-throughput

0.279

Low

1388947

ARSG
Arylsulfatase G

1

0

High-throughput

0.279

Low

1398243

H6ST2
Heparan-sulfate 6-O-sulfotransferase 2

1

0

High-throughput

0.279

Low

1411475

EDEM3
ER degradation-enhancing alpha-mannosidase-like protein 3

1

0

High-throughput

0.279

Low

1411476

CHRD
Chordin

1

0

High-throughput

0.279

Low

1411478

TOR3A
Torsin-3A

1

0

High-throughput

0.279

Low

1411479

TBB1
Tubulin beta-1 chain

1

0

High-throughput

0.279

Low

1411482

P4HTM
Transmembrane prolyl 4-hydroxylase

1

0

High-throughput

0.279

Low

1411483

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.279

Low

1411484

TMEM9
Proton-transporting V-type ATPase complex assembly regulator TMEM9

1

0

High-throughput

0.279

Low

1411486

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.279

Low

1411488

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

1411492

MA2B2
Epididymis-specific alpha-mannosidase

1

0

High-throughput

0.279

Low

1257117

PAXI1
PAX-interacting protein 1

1

0

High-throughput

0.251

Low

1411477

IFG15
Torsin-1A-interacting protein 2, isoform IFRG15

1

0

High-throughput

0.249

Low

1175891

TM241
UDP-N-acetylglucosamine transporter TMEM241

1

0

High-throughput

0.232

Low

1313984

S35F3
Solute carrier family 35 member F3

1

0

High-throughput

0.232

Low

1339451

TOIP2
Torsin-1A-interacting protein 2

1

0

High-throughput

0.232

Low

1411491

S35A3
UDP-N-acetylglucosamine transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025