Protein: MLC1
Membrane protein MLC1 (Megalencephalic leukoencephalopathy with subcortical cysts protein 1)

Gene: MLC1
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q15049

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005764 - lysosome
GO:0005768 - endosome
GO:0005769 - early endosome
GO:0005783 - endoplasmic reticulum

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1008036

KCJ10
ATP-sensitive inward rectifier potassium channel 10

2

0

Small-scale

0.559

High

451160

NFL
Neurofilament light polypeptide

1

1

High-throughput

0.515

High

570429

GFAP
Glial fibrillary acidic protein

1

1

High-throughput

0.515

High

541495

FGFR1
Fibroblast growth factor receptor 1

1

0

High-throughput

0.513

High

1139899

NOMO1
BOS complex subunit NOMO1

1

0

High-throughput

0.513

High

1139902

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

1139903

MZT2B
Mitotic-spindle organizing protein 2B

1

0

High-throughput

0.513

High

1139906

YTHD1
YTH domain-containing family protein 1

1

0

High-throughput

0.513

High

1139907

PGES2
Prostaglandin E synthase 2

1

0

High-throughput

0.513

High

245944

KIF1B
Kinesin-like protein KIF1B

1

0

High-throughput

0.493

High

301431

WFS1
Wolframin

1

0

High-throughput

0.493

High

415583

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.493

High

954475

PRPS1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.493

High

1139904

JPH3
Junctophilin-3

1

0

High-throughput

0.493

High

1139908

ATX10
Ataxin-10

1

0

High-throughput

0.493

High

1139909

RNF11
RING finger protein 11

1

0

High-throughput

0.493

High

1106266

ROCK1
Rho-associated protein kinase 1

1

0

Small-scale

0.480

High

1139901

MYLK
Myosin light chain kinase, smooth muscle

1

0

Small-scale

0.480

High

262386

DTNB
Dystrobrevin beta

1

1

Small-scale

0.479

High

1139910

DTNA
Dystrobrevin alpha

1

1

Small-scale

0.479

High

791395

SYUA
Alpha-synuclein

1

0

High-throughput

0.460

High

420797

AT1B1
Sodium/potassium-transporting ATPase subunit beta-1

1

0

Small-scale

0.458

High

1041071

CAV1
Caveolin-1

1

0

Small-scale

0.458

High

1104787

SNTA1
Alpha-1-syntrophin

1

0

Small-scale

0.458

High

329266

LETM1
Mitochondrial proton/calcium exchanger protein

1

0

High-throughput

0.279

Low

1129597

MDC1
Mediator of DNA damage checkpoint protein 1

1

0

High-throughput

0.279

Low

1025104

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.268

Low

1031899

NC2B
Protein Dr1

1

0

High-throughput

0.268

Low

1096008

TADBP
TAR DNA-binding protein 43

1

0

High-throughput

0.268

Low

1139911

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.268

Low

246610

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.265

Low

1139905

ANM6
Protein arginine N-methyltransferase 6

1

0

High-throughput

0.265

Low

1139900

ZMY11
Zinc finger MYND domain-containing protein 11

1

0

High-throughput

0.261

Low

105962

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025