Protein: C8AP2
CASP8-associated protein 2 (FLICE-associated huge protein)

Gene: C8AP2, CASP8AP2
Organism: Homo sapiens
Interactions: 51
UniProt ID: Q9UKL3

Gene Ontology (top 5):
GO:0003714 - transcription corepressor activity
GO:0005123 - death receptor binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

993805

UBC9
SUMO-conjugating enzyme UBC9

3

1

Small-scale

0.658

High

1110171

HDAC1
Histone deacetylase 1

3

0

High-throughput

0.638

High

1132464

CASP8
Caspase-8

2

1

Small-scale

0.616

High

1460447

SCOC
Short coiled-coil protein

2

0

High-throughput

0.602

High

1461126

RCOR1
REST corepressor 1

2

0

High-throughput

0.585

High

964504

SUMO2
Small ubiquitin-related modifier 2

1

2

Small-scale

0.561

High

1090974

TRAF2
TNF receptor-associated factor 2

1

1

Small-scale

0.561

High

297711

PIAS1
E3 SUMO-protein ligase PIAS1

1

0

Small-scale

0.549

High

1085485

SRBP2
Sterol regulatory element-binding protein 2

1

1

High-throughput

0.541

High

578733

GLNA
Glutamine synthetase

1

0

High-throughput

0.518

High

1096939

FADD
FAS-associated death domain protein

1

2

Small-scale

0.515

High

1369563

CASPA
Caspase-10

1

1

Small-scale

0.508

High

659315

SP100
Nuclear autoantigen Sp-100

1

0

Small-scale

0.506

High

467803

MCR
Mineralocorticoid receptor

1

1

Small-scale

0.481

High

714508

PML
Protein PML

1

1

High-throughput

0.481

High

833698

NAA10
N-alpha-acetyltransferase 10

1

1

High-throughput

0.481

High

940472

TCL1A
T-cell leukemia/lymphoma protein 1A

1

1

High-throughput

0.481

High

404532

GCR
Glucocorticoid receptor

1

1

Small-scale

0.479

High

991458

SUMO1
Small ubiquitin-related modifier 1

1

2

Small-scale

0.479

High

1339025

NUP43
Nucleoporin Nup43

1

1

High-throughput

0.479

High

623589

RO52
E3 ubiquitin-protein ligase TRIM21

1

0

Small-scale

0.460

High

633400

MX1
Interferon-induced GTP-binding protein Mx1

1

0

Small-scale

0.460

High

941599

CTBP2
C-terminal-binding protein 2

1

0

High-throughput

0.460

High

1040652

CREM
cAMP-responsive element modulator

1

0

High-throughput

0.460

High

1056000

RAD51
DNA repair protein RAD51 homolog 1

1

0

Small-scale

0.460

High

1368525

CBP
CREB-binding protein

1

0

Small-scale

0.460

High

1461154

KLH20
Kelch-like protein 20

1

0

Small-scale

0.460

High

186817

P73
Tumor protein p73

1

0

Small-scale

0.458

High

243255

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

247020

KDM1A
Lysine-specific histone demethylase 1A

1

0

High-throughput

0.458

High

260593

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

675200

TNR6
Tumor necrosis factor receptor superfamily member 6

1

0

Small-scale

0.458

High

679282

DNJB1
DnaJ homolog subfamily B member 1

1

0

High-throughput

0.458

High

685769

U2AF2
Splicing factor U2AF 65 kDa subunit

1

0

High-throughput

0.458

High

800160

COIL
Coilin

1

0

High-throughput

0.458

High

801577

HSPA9
Stress-70 protein, mitochondrial

1

0

High-throughput

0.458

High

980520

H4
Histone H4

1

0

High-throughput

0.458

High

1015330

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.458

High

1060243

B2CL1
Bcl-2-like protein 1

1

0

Small-scale

0.458

High

1124141

NPAT
Protein NPAT

1

0

Small-scale

0.458

High

1135848

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

1368776

SYMPK
Symplekin

1

0

High-throughput

0.458

High

1372338

H2B1H
Histone H2B type 1-H

1

0

High-throughput

0.458

High

1384472

PF21A
PHD finger protein 21A

1

0

High-throughput

0.458

High

1387630

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

0

High-throughput

0.458

High

1461152

C8AP2
CASP8-associated protein 2

1

0

Small-scale

0.458

High

1461153

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

1461155

TRRAP
Transformation/transcription domain-associated protein

1

0

High-throughput

0.458

High

1399143

CF418
Cilia- and flagella-associated protein 418

1

0

Small-scale

0.438

High

1278483

PLGT3
Protein O-glucosyltransferase 3

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025