Protein: PROX1
Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1)

Gene: PROX1
Organism: Homo sapiens
Interactions: 43
UniProt ID: Q92786

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

834007

HNF4A
Hepatocyte nuclear factor 4-alpha

2

2

Small-scale

0.615

High

137545

NR5A2
Nuclear receptor subfamily 5 group A member 2

2

5

Small-scale

0.614

High

976915

ERR3
Estrogen-related receptor gamma

2

2

High-throughput

0.614

High

1066424

RBBP4
Histone-binding protein RBBP4

2

0

High-throughput

0.576

High

941511

CTBP2
C-terminal-binding protein 2

1

2

High-throughput

0.573

High

1067563

EP300
Histone acetyltransferase p300

1

2

Small-scale

0.552

High

682566

S100P
Protein S100-P

1

1

High-throughput

0.536

High

1122422

GIT2
ARF GTPase-activating protein GIT2

1

0

High-throughput

0.518

High

1145829

IRF4
Interferon regulatory factor 4

1

0

High-throughput

0.518

High

1200223

LBH
Protein LBH

1

0

High-throughput

0.518

High

1368423

ZBTB3
Zinc finger and BTB domain-containing protein 3

1

0

High-throughput

0.518

High

188329

HDAC3
Histone deacetylase 3

1

3

Small-scale

0.515

High

1340896

MB3L2
Methyl-CpG-binding domain protein 3-like 2

1

0

High-throughput

0.513

High

1368425

CYH4
Cytohesin-4

1

0

High-throughput

0.513

High

635207

HNF1A
Hepatocyte nuclear factor 1-alpha

1

0

Small-scale

0.493

High

1043718

CEBPZ
CCAAT/enhancer-binding protein zeta

1

0

High-throughput

0.493

High

706245

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

467793

MCR
Mineralocorticoid receptor

1

3

High-throughput

0.481

High

543586

ERR1
Steroid hormone receptor ERR1

1

2

High-throughput

0.481

High

771009

RORA
Nuclear receptor ROR-alpha

1

4

High-throughput

0.481

High

1041781

PPARD
Peroxisome proliferator-activated receptor delta

1

3

High-throughput

0.481

High

685290

PAX6
Paired box protein Pax-6

1

0

Small-scale

0.480

High

143156

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

174578

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.479

High

260245

BRD4
Bromodomain-containing protein 4

1

1

High-throughput

0.479

High

474169

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

789537

PPARG
Peroxisome proliferator-activated receptor gamma

1

4

Small-scale

0.479

High

1087907

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1133570

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.479

High

1141247

BRD3
Bromodomain-containing protein 3

1

3

High-throughput

0.479

High

1014566

SMAD3
Mothers against decapentaplegic homolog 3

1

0

High-throughput

0.460

High

378438

IFNG
Interferon gamma

1

0

Small-scale

0.458

High

412370

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.458

High

629982

BTF3
Transcription factor BTF3

1

0

High-throughput

0.458

High

904989

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

991387

SUMO1
Small ubiquitin-related modifier 1

1

0

Small-scale

0.458

High

1132870

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

0

High-throughput

0.458

High

1368422

FGF11
Fibroblast growth factor 11

1

0

High-throughput

0.458

High

1368424

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1368426

BRPF3
Bromodomain and PHD finger-containing protein 3

1

0

High-throughput

0.458

High

1101140

STF1
Steroidogenic factor 1

1

5

Small-scale

0.457

High

1103301

CTBP1
C-terminal-binding protein 1

1

2

High-throughput

0.445

High

1368022

HDAC2
Histone deacetylase 2

1

3

High-throughput

0.445

High


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Last updated: 11Aug2025