Protein: DKK1
Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK)

Gene: DKK1
Organism: Homo sapiens
Interactions: 23
UniProt ID: O94907

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000902 - cell morphogenesis
GO:0001706 - endoderm formation
GO:0001707 - mesoderm formation
GO:0001942 - hair follicle development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

287503

LRP6
Low-density lipoprotein receptor-related protein 6

7

8

Small-scale

0.974

High

274845

LRP5
Low-density lipoprotein receptor-related protein 5

3

8

High-throughput

0.861

High

321726

KREM1
Kremen protein 1

2

1

Small-scale

0.768

High

321725

KREM2
Kremen protein 2

1

1

High-throughput

0.691

High

321727

MDFI
MyoD family inhibitor

3

0

High-throughput

0.643

High

321713

POTEI
POTE ankyrin domain family member I

3

0

High-throughput

0.638

High

321721

PSMD6
26S proteasome non-ATPase regulatory subunit 6

2

0

High-throughput

0.585

High

321720

CKAP4
Cytoskeleton-associated protein 4

1

0

Small-scale

0.537

High

321718

KR101
Keratin-associated protein 10-1

2

1

High-throughput

0.526

High

321715

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.518

High

321716

COR1A
Coronin-1A

1

0

High-throughput

0.493

High

321722

PREP
Presequence protease, mitochondrial

1

1

High-throughput

0.489

High

321714

FBLN1
Fibulin-1

1

2

High-throughput

0.479

High

321711

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

0

High-throughput

0.458

High

321712

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

0

High-throughput

0.458

High

321717

CTNB1
Catenin beta-1

1

0

Small-scale

0.458

High

321719

VIGLN
Vigilin

1

0

High-throughput

0.458

High

321729

PSD13
26S proteasome non-ATPase regulatory subunit 13

1

0

High-throughput

0.458

High

122989

KITM
Thymidine kinase 2, mitochondrial

3

0

High-throughput

0.347

High

321724

RBM45
RNA-binding protein 45

3

0

High-throughput

0.347

High

181844

SMAD9
Mothers against decapentaplegic homolog 9

1

0

High-throughput

0.265

Low

321723

AMZ2
Archaemetzincin-2

1

0

High-throughput

0.249

Low

321728

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025