Protein: IGS21
Immunoglobulin superfamily member 21 (IgSF21)

Gene: IGS21, IGSF21
Organism: Homo sapiens
Interactions: 40
UniProt ID: Q96ID5

Gene Ontology (top 5):
GO:0005912 - adherens junction
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0009897 - external side of plasma membrane
GO:0042734 - presynaptic membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1394150

PCDA4
Protocadherin alpha-4

1

0

High-throughput

0.663

High

1361106

CCG8
Voltage-dependent calcium channel gamma-8 subunit

1

0

High-throughput

0.656

High

482261

PAEP
Glycodelin

1

0

High-throughput

0.584

High

540072

BCR
Breakpoint cluster region protein

1

0

High-throughput

0.584

High

895501

SPB9
Serpin B9

1

0

High-throughput

0.584

High

1162655

DGKD
Diacylglycerol kinase delta

1

0

High-throughput

0.584

High

892160

GRAK
Granzyme K

1

0

High-throughput

0.578

High

375838

RASK
GTPase KRas

1

0

High-throughput

0.549

High

891737

GSK3B
Glycogen synthase kinase-3 beta

1

0

High-throughput

0.549

High

128040

PSD11
26S proteasome non-ATPase regulatory subunit 11

1

0

High-throughput

0.282

High

325444

RPP14
Ribonuclease P protein subunit p14

1

0

High-throughput

0.282

High

339376

ETHE1
Persulfide dioxygenase ETHE1, mitochondrial

1

0

High-throughput

0.282

High

415787

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.282

High

423927

ALDH2
Aldehyde dehydrogenase, mitochondrial

1

0

High-throughput

0.282

High

424249

S10A8
Protein S100-A8

1

0

High-throughput

0.282

High

553729

ANXA3
Annexin A3

1

0

High-throughput

0.282

High

617181

ATF3
Cyclic AMP-dependent transcription factor ATF-3

1

0

High-throughput

0.282

High

892184

ST1E1
Sulfotransferase 1E1

1

0

High-throughput

0.282

High

892306

SPS1
Selenide, water dikinase 1

1

0

High-throughput

0.282

High

1015280

ERH
Enhancer of rudimentary homolog

1

0

High-throughput

0.282

High

1040478

GSTM4
Glutathione S-transferase Mu 4

1

0

High-throughput

0.282

High

1117127

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.282

High

1136754

MD2BP
MAD2L1-binding protein

1

0

High-throughput

0.282

High

1142455

PA1B3
Platelet-activating factor acetylhydrolase IB subunit alpha1

1

0

High-throughput

0.282

High

1154285

UB2V2
Ubiquitin-conjugating enzyme E2 variant 2

1

0

High-throughput

0.282

High

1159458

NREP
Neuronal regeneration-related protein

1

0

High-throughput

0.282

High

1353624

GIPC2
PDZ domain-containing protein GIPC2

1

0

High-throughput

0.282

High

1394146

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.282

High

1394147

BTBD2
BTB/POZ domain-containing protein 2

1

0

High-throughput

0.282

High

1394149

CRCT1
Cysteine-rich C-terminal protein 1

1

0

High-throughput

0.282

High

771602

HXD13
Homeobox protein Hox-D13

1

0

High-throughput

0.279

Low

1207003

ZNG1C
Zinc-regulated GTPase metalloprotein activator 1C

1

0

High-throughput

0.279

Low

1253976

RBPS2
RNA-binding protein with multiple splicing 2

1

0

High-throughput

0.279

Low

1277272

MIER3
Mesoderm induction early response protein 3

1

0

High-throughput

0.279

Low

1394148

TBB1
Tubulin beta-1 chain

1

0

High-throughput

0.279

Low

665281

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

High-throughput

0.265

Low

461812

HS90A
Heat shock protein HSP 90-alpha

1

0

High-throughput

0.249

Low

974956

TYB4
Thymosin beta-4

1

0

High-throughput

0.238

Low

1394152

E41L3
Band 4.1-like protein 3

1

0

High-throughput

0.238

Low

1394151

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025