Protein: GPAA1
GPI-anchor transamidase component GPAA1 (GAA1 protein homolog) (hGAA1) (Glycosylphosphatidylinositol anchor attachment 1 protein) (GPI anchor attachment protein 1)

Gene: GPAA1
Organism: Homo sapiens
Interactions: 102
UniProt ID: O43292

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0005813 - centrosome
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

212592

GPI8
GPI-anchor transamidase

8

1

Small-scale

0.962

High

212595

PIGT
GPI-anchor transamidase component PIGT

5

1

Small-scale

0.931

High

212598

PIGS
GPI-anchor transamidase component PIGS

5

1

Small-scale

0.700

High

212613

TSP50
Probable threonine protease PRSS50

2

2

High-throughput

0.611

High

212575

ZACN
Ligand-gated cation channel ZACN

3

2

High-throughput

0.609

High

212567

TP4A2
Protein tyrosine phosphatase type IVA 2

2

0

High-throughput

0.602

High

212579

MOXD1
DBH-like monooxygenase protein 1

2

0

High-throughput

0.602

High

211962

TREA
Trehalase

2

0

High-throughput

0.585

High

212599

KCNKG
Potassium channel subfamily K member 16

2

0

High-throughput

0.585

High

212606

PIGU
GPI-anchor transamidase component PIGU

1

1

High-throughput

0.575

High

212541

GBRG2
Gamma-aminobutyric acid receptor subunit gamma-2

2

2

High-throughput

0.574

High

212549

AGTR1
Type-1 angiotensin II receptor

1

1

High-throughput

0.541

High

182419

GP182
G-protein coupled receptor 182

1

2

High-throughput

0.536

High

212525

AP1G2
AP-1 complex subunit gamma-like 2

1

1

High-throughput

0.536

High

212530

TSN15
Tetraspanin-15

1

1

High-throughput

0.536

High

212534

ATPB
ATP synthase F(1) complex subunit beta, mitochondrial

1

1

High-throughput

0.536

High

212545

FPR2
N-formyl peptide receptor 2

1

2

High-throughput

0.536

High

212550

GNRHR
Gonadotropin-releasing hormone receptor

1

0

High-throughput

0.518

High

212561

EIF3E
Eukaryotic translation initiation factor 3 subunit E

1

0

High-throughput

0.518

High

212568

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

0

High-throughput

0.518

High

212521

SNG1
Synaptogyrin-1

1

0

High-throughput

0.513

High

212524

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.513

High

212527

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

0

High-throughput

0.513

High

212529

STR3N
STARD3 N-terminal-like protein

1

0

High-throughput

0.513

High

212532

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.513

High

212535

CD7
T-cell antigen CD7

1

0

High-throughput

0.513

High

212536

IFI6
Interferon alpha-inducible protein 6

1

0

High-throughput

0.513

High

212537

COX41
Cytochrome c oxidase subunit 4 isoform 1, mitochondrial

1

0

High-throughput

0.513

High

212540

DPEP1
Dipeptidase 1

1

0

High-throughput

0.513

High

212546

STOM
Stomatin

1

0

High-throughput

0.513

High

212557

PI2R
Prostacyclin receptor

1

0

High-throughput

0.513

High

212563

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.513

High

212581

HS2ST
Heparan sulfate 2-O-sulfotransferase 1

1

0

High-throughput

0.513

High

212585

CGAT2
Chondroitin sulfate N-acetylgalactosaminyltransferase 2

1

0

High-throughput

0.513

High

212588

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.513

High

212596

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.513

High

212597

CREL1
Protein disulfide isomerase CRELD1

1

0

High-throughput

0.513

High

212605

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

212612

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.513

High

212615

FBX2
F-box only protein 2

1

0

High-throughput

0.513

High

212618

ENTP2
Ectonucleoside triphosphate diphosphohydrolase 2

1

0

High-throughput

0.513

High

212543

PPIB
Peptidyl-prolyl cis-trans isomerase B

1

0

High-throughput

0.493

High

212562

1433G
14-3-3 protein gamma

1

0

High-throughput

0.493

High

212593

KAT5
Histone acetyltransferase KAT5

1

0

High-throughput

0.493

High

212542

TSN8
Tetraspanin-8

1

1

High-throughput

0.489

High

212551

GBRA3
Gamma-aminobutyric acid receptor subunit alpha-3

1

2

High-throughput

0.489

High

212556

P2RY2
P2Y purinoceptor 2

1

1

High-throughput

0.489

High

212558

5HT3A
5-hydroxytryptamine receptor 3A

1

1

High-throughput

0.489

High

212555

AQP2
Aquaporin-2

1

1

Small-scale

0.481

High

212522

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

212548

NDUS1
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial

1

0

High-throughput

0.458

High

212554

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.458

High

212571

ACAP2
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2

1

0

High-throughput

0.458

High

212559

S6A12
Sodium- and chloride-dependent betaine transporter

1

1

High-throughput

0.445

High

212569

S39AE
Metal cation symporter ZIP14

1

1

High-throughput

0.445

High

212604

S6A15
Sodium-dependent neutral amino acid transporter B(0)AT2

1

1

High-throughput

0.445

High

212572

GRIK5
Glutamate receptor ionotropic, kainate 5

1

0

High-throughput

0.438

High

212611

PRR13
Proline-rich protein 13

1

0

High-throughput

0.438

High

212565

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

2

High-throughput

0.437

High

212590

5HT3C
5-hydroxytryptamine receptor 3C

1

1

High-throughput

0.437

High

212616

ALK
ALK tyrosine kinase receptor

1

1

Small-scale

0.437

High

212523

FADS1
Acyl-CoA

1

0

High-throughput

0.426

High

212531

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

0

High-throughput

0.426

High

212544

AT5F1
ATP synthase peripheral stalk subunit b, mitochondrial

1

0

High-throughput

0.426

High

212566

S35A2
UDP-galactose translocator

1

0

High-throughput

0.426

High

212577

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.426

High

212586

CTL5
Choline transporter-like protein 5

1

0

High-throughput

0.426

High

212602

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.426

High

212603

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

212600

S39A8
Metal cation symporter ZIP8

1

1

High-throughput

0.407

High

212608

S35C2
Solute carrier family 35 member C2

1

1

High-throughput

0.407

High

212526

LYPD3
Ly6/PLAUR domain-containing protein 3

3

0

High-throughput

0.347

High

212528

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.328

High

212601

YIPF3
Protein YIPF3

2

0

High-throughput

0.328

High

212578

TECT3
Tectonic-3

2

0

High-throughput

0.318

High

212591

LPAR1
Lysophosphatidic acid receptor 1

2

0

High-throughput

0.318

High

212538

GPIX
Platelet glycoprotein IX

1

0

High-throughput

0.279

Low

212553

SCN4A
Sodium channel protein type 4 subunit alpha

1

0

High-throughput

0.279

Low

212560

EFNA4
Ephrin-A4

1

0

High-throughput

0.279

Low

212573

PRSS8
Prostasin

1

0

High-throughput

0.279

Low

212574

TMM95
Sperm-egg fusion protein TMEM95

1

0

High-throughput

0.279

Low

212576

RTP2
Receptor-transporting protein 2

1

0

High-throughput

0.279

Low

212584

CA2D3
Voltage-dependent calcium channel subunit alpha-2/delta-3

1

0

High-throughput

0.279

Low

212594

NAR4
Ecto-ADP-ribosyltransferase 4

1

0

High-throughput

0.279

Low

212609

GP173
Probable G-protein coupled receptor 173

1

0

High-throughput

0.279

Low

212614

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.279

Low

212617

B3GN3
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 3

1

0

High-throughput

0.279

Low

212570

SETB1
Histone-lysine N-methyltransferase SETDB1

1

0

High-throughput

0.268

Low

212587

LMO3
LIM domain only protein 3

1

0

High-throughput

0.268

Low

212519

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

212533

PPB1
Alkaline phosphatase, placental type

1

0

Small-scale

0.249

Low

212539

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

212547

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

212552

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

212564

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

212580

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

212582

FA20C
Extracellular serine/threonine protein kinase FAM20C

1

0

High-throughput

0.249

Low

212589

MCLN3
Mucolipin-3

1

0

High-throughput

0.249

Low

212607

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

212610

T106B
Transmembrane protein 106B

1

0

High-throughput

0.249

Low

212520

PSCA
Prostate stem cell antigen

1

0

High-throughput

0.232

Low

212583

S15A3
Solute carrier family 15 member 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025