Protein: ZBTB3
Zinc finger and BTB domain-containing protein 3

Gene: ZBTB3
Organism: Homo sapiens
Interactions: 56
UniProt ID: Q9H5J0

Gene Ontology (top 5):
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008270 - zinc ion binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1405526

ZBT18
Zinc finger and BTB domain-containing protein 18

2

18

High-throughput

0.811

High

913809

ZN131
Zinc finger protein 131

2

19

High-throughput

0.789

High

1428943

ANKR2
Ankyrin repeat domain-containing protein 2

1

6

High-throughput

0.698

High

1434612

ZN556
Zinc finger protein 556

1

10

High-throughput

0.698

High

51768

ZBT7C
Zinc finger and BTB domain-containing protein 7C

1

19

High-throughput

0.691

High

208900

ZBT24
Zinc finger and BTB domain-containing protein 24

1

19

High-throughput

0.691

High

1434617

ZN212
Zinc finger protein 212

1

19

High-throughput

0.691

High

1434618

FXL17
F-box/LRR-repeat protein 17

1

10

High-throughput

0.691

High

1333283

KLH23
Kelch-like protein 23

1

20

High-throughput

0.618

High

1434615

KLH28
Kelch-like protein 28

1

20

High-throughput

0.618

High

1434619

KLH21
Kelch-like protein 21

1

20

High-throughput

0.618

High

227667

SPOP
Speckle-type POZ protein

1

20

Small-scale

0.618

High

1332941

SMYD1
Histone-lysine N-methyltransferase SMYD1

2

3

High-throughput

0.606

High

1417305

AP1M1
AP-1 complex subunit mu-1

2

8

High-throughput

0.553

High

130615

SPT5H
Transcription elongation factor SPT5

1

4

High-throughput

0.541

High

138526

BIN1
Myc box-dependent-interacting protein 1

1

2

High-throughput

0.541

High

167193

IRF6
Interferon regulatory factor 6

1

7

High-throughput

0.541

High

404423

GCR
Glucocorticoid receptor

1

20

High-throughput

0.541

High

533306

THA
Thyroid hormone receptor alpha

1

20

High-throughput

0.541

High

789573

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

High-throughput

0.541

High

851668

GATA4
Transcription factor GATA-4

1

8

High-throughput

0.541

High

938184

PKNX1
Homeobox protein PKNOX1

1

2

High-throughput

0.541

High

1014617

SMAD3
Mothers against decapentaplegic homolog 3

1

5

High-throughput

0.541

High

1061614

FOXM1
Forkhead box protein M1

1

17

High-throughput

0.541

High

1408100

SSX3
Protein SSX3

1

2

High-throughput

0.541

High

1434613

JADE2
E3 ubiquitin-protein ligase Jade-2

1

9

High-throughput

0.541

High

1434616

ZMYM2
Zinc finger MYM-type protein 2

1

10

High-throughput

0.541

High

1434620

LEF1
Lymphoid enhancer-binding factor 1

1

20

High-throughput

0.541

High

1434625

NEMO
NF-kappa-B essential modulator

1

11

High-throughput

0.541

High

900159

FXR1
RNA-binding protein FXR1

1

16

High-throughput

0.536

High

900511

FXR2
RNA-binding protein FXR2

1

16

High-throughput

0.536

High

1029757

FOXK2
Forkhead box protein K2

1

13

High-throughput

0.536

High

1056974

FMR1
Fragile X messenger ribonucleoprotein 1

1

16

High-throughput

0.536

High

1246162

TRAF7
E3 ubiquitin-protein ligase TRAF7

1

11

High-throughput

0.536

High

1434614

SMYD2
N-lysine methyltransferase SMYD2

1

3

High-throughput

0.536

High

1434621

SNX6
Sorting nexin-6

1

6

High-throughput

0.536

High

1368423

PROX1
Prospero homeobox protein 1

1

0

High-throughput

0.518

High

1434622

TF2AY
TFIIA-alpha and beta-like factor

1

0

High-throughput

0.518

High

555523

SKIL
Ski-like protein

1

1

High-throughput

0.508

High

258183

IF2P
Eukaryotic translation initiation factor 5B

1

4

High-throughput

0.494

High

61637

VWA8
von Willebrand factor A domain-containing protein 8

1

4

High-throughput

0.489

High

230108

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

1

2

High-throughput

0.489

High

344796

AP2A1
AP-2 complex subunit alpha-1

1

5

High-throughput

0.489

High

1111975

SNX1
Sorting nexin-1

1

6

High-throughput

0.489

High

1333334

NHLC2
NHL repeat-containing protein 2

1

1

High-throughput

0.489

High

1393315

SAHH3
Adenosylhomocysteinase 3

1

2

High-throughput

0.489

High

1421062

ZY11B
Protein zyg-11 homolog B

1

1

High-throughput

0.489

High

1434623

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

2

High-throughput

0.489

High

1434624

SNX5
Sorting nexin-5

1

6

High-throughput

0.489

High

347932

BAG3
BAG family molecular chaperone regulator 3

1

5

High-throughput

0.479

High

887224

CEBPA
CCAAT/enhancer-binding protein alpha

1

19

High-throughput

0.479

High

983977

RBX1
E3 ubiquitin-protein ligase RBX1

1

3

Small-scale

0.479

High

1042077

LMNB2
Lamin-B2

1

10

High-throughput

0.470

High

1395463

MY15B
Unconventional myosin-XVB

1

11

High-throughput

0.470

High

63869

TPC13
Trafficking protein particle complex subunit 13

1

0

High-throughput

0.279

Low

1434611

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025