Interactor 1: SOCS2 (O14508)
Suppressor of cytokine signaling 2 (SOCS-2) (Cytokine-inducible SH2 protein 2) (CIS-2) (STAT-induced STAT inhibitor 2) (SSI-2)
Gene: SOCS2
Interactor 2: PRLR (P16471)
Prolactin receptor (PRL-R)
Gene: PRLR
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 0.60 | 0.479 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10455112 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | - |
| Common GO terms | GO:0007259 - cell surface receptor signaling pathway via JAK-STAT GO:0007595 - lactation GO:0019221 - cytokine-mediated signaling pathway GO:0043066 - negative regulation of apoptotic process GO:0060749 - mammary gland alveolus development |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Last updated: 11Aug2025