Protein: DUOX2
Dual oxidase 2 (EC 1.11.1.-) (EC 1.6.3.1) (Large NOX 2) (Long NOX 2) (NADH/NADPH thyroid oxidase p138-tox) (NADPH oxidase/peroxidase DUOX2) (NADPH thyroid oxidase 2) (Thyroid oxidase 2) (p138 thyroid oxidase)

Gene: DUOX2
Organism: Homo sapiens
Interactions: 30
UniProt ID: Q9NRD8

Gene Ontology (top 5):
GO:0004601 - peroxidase activity
GO:0005509 - calcium ion binding
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1168755

DOXA2
Dual oxidase maturation factor 2

1

2

Small-scale

0.690

High

157900

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

256999

H2B1K
Histone H2B type 1-K

1

12

High-throughput

0.479

High

419225

H2A1B
Histone H2A type 1-B/E

1

3

High-throughput

0.479

High

449796

H2B1J
Histone H2B type 1-J

1

12

High-throughput

0.479

High

591854

H2AX
Histone H2AX

1

3

High-throughput

0.479

High

634069

H2A1D
Histone H2A type 1-D

1

3

High-throughput

0.479

High

659950

H2B1O
Histone H2B type 1-O

1

12

High-throughput

0.479

High

754999

H2B1B
Histone H2B type 1-B

1

12

High-throughput

0.479

High

943423

H2BFS
Histone H2B type F-S

1

12

High-throughput

0.479

High

946891

H2B1D
Histone H2B type 1-D

1

12

High-throughput

0.479

High

1163229

H2B2E
Histone H2B type 2-E

1

12

High-throughput

0.479

High

1208898

H2B2F
Histone H2B type 2-F

1

12

High-throughput

0.479

High

1272824

H2A3
Histone H2A type 3

1

3

High-throughput

0.479

High

1323988

H2B3B
Histone H2B type 3-B

1

12

High-throughput

0.479

High

1372316

H2B1H
Histone H2B type 1-H

1

12

High-throughput

0.479

High

1407998

H2B1N
Histone H2B type 1-N

1

12

High-throughput

0.479

High

1408057

H2B1L
Histone H2B type 1-L

1

12

High-throughput

0.479

High

1448415

UBP25
Ubiquitin carboxyl-terminal hydrolase 25

1

6

High-throughput

0.479

High

1448416

TENN
Tenascin-N

1

1

High-throughput

0.479

High

1107248

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1438560

NOD2
Nucleotide-binding oligomerization domain-containing protein 2

1

0

Small-scale

0.458

High

1448417

PCLO
Protein piccolo

1

0

High-throughput

0.458

High

1245622

TXD11
Thioredoxin domain-containing protein 11

1

2

Small-scale

0.437

High

1448414

CAMP3
Calmodulin-regulated spectrin-associated protein 3

1

2

High-throughput

0.437

High

377740

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

542669

TOP2A
DNA topoisomerase 2-alpha

1

0

High-throughput

0.249

Low

946262

ATS12
A disintegrin and metalloproteinase with thrombospondin motifs 12

1

0

High-throughput

0.249

Low

1211618

TEX35
Testis-expressed protein 35

1

0

High-throughput

0.249

Low

1247561

ZN474
Zinc finger protein 474

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025