Protein: NKG2E
NKG2-E type II integral membrane protein (NK cell receptor E) (NKG2-E-activating NK receptor)

Gene: NKG2E, KLRC3
Organism: Homo sapiens
Interactions: 28
UniProt ID: Q07444

Gene Ontology (top 5):
GO:0002223 - stimulatory C-type lectin receptor signaling pathway
GO:0004888 - transmembrane signaling receptor activity
GO:0005886 - plasma membrane
GO:0006968 - cellular defense response
GO:0009897 - external side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1059326

LRRC3
Leucine-rich repeat-containing protein 3

1

12

High-throughput

0.691

High

700782

DMB
HLA class II histocompatibility antigen, DM beta chain

1

20

High-throughput

0.618

High

1059331

SE1L1
Protein sel-1 homolog 1

1

9

High-throughput

0.618

High

1059313

KLRD1
Natural killer cells antigen CD94

1

16

Small-scale

0.618

High

249041

NRP2
Neuropilin-2

1

12

High-throughput

0.536

High

582159

INGR1
Interferon gamma receptor 1

1

2

High-throughput

0.536

High

612067

ITB5
Integrin beta-5

1

13

High-throughput

0.536

High

942339

BACE1
Beta-secretase 1

1

4

High-throughput

0.536

High

1059314

STIM1
Stromal interaction molecule 1

1

2

High-throughput

0.536

High

1059316

SGCB
Beta-sarcoglycan

1

3

High-throughput

0.536

High

1059319

GLT13
Polypeptide N-acetylgalactosaminyltransferase 13

1

14

High-throughput

0.536

High

1059320

SIDT2
SID1 transmembrane family member 2

1

3

High-throughput

0.536

High

1059324

S47A1
Multidrug and toxin extrusion protein 1

1

4

High-throughput

0.536

High

1059328

RN167
E3 ubiquitin-protein ligase RNF167

1

8

High-throughput

0.536

High

1059332

LRP12
Low-density lipoprotein receptor-related protein 12

1

15

High-throughput

0.536

High

1059317

RHOU
Rho-related GTP-binding protein RhoU

1

18

High-throughput

0.501

High

220494

RNF13
E3 ubiquitin-protein ligase RNF13

1

9

High-throughput

0.489

High

1059312

TMM62
Transmembrane protein 62

1

3

High-throughput

0.489

High

1059318

D19L4
Probable C-mannosyltransferase DPY19L4

1

1

High-throughput

0.489

High

1059321

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

1

6

High-throughput

0.489

High

1059322

TM9S4
Transmembrane 9 superfamily member 4

1

4

High-throughput

0.489

High

1059327

PIGM
GPI alpha-1,4-mannosyltransferase I, catalytic subunit

1

1

High-throughput

0.489

High

1059329

AT132
Polyamine-transporting ATPase 13A2

1

18

High-throughput

0.489

High

1059330

TM181
Transmembrane protein 181

1

1

High-throughput

0.489

High

1025256

CDK3
Cyclin-dependent kinase 3

1

0

High-throughput

0.279

Low

1059323

TMM18
Transmembrane protein 18

1

0

High-throughput

0.279

Low

1059325

TECT2
Tectonic-2

1

0

High-throughput

0.279

Low

1059315

NCOA2
Nuclear receptor coactivator 2

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025