Protein: PIGM
GPI alpha-1,4-mannosyltransferase I, catalytic subunit (EC 2.4.1.-) (GPI mannosyltransferase I) (GPI-MT-I) (Phosphatidylinositol-glycan biosynthesis class M protein) (PIG-M)

Gene: PIGM
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q9H3S5

Gene Ontology (top 5):
GO:0000030 - mannosyltransferase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006506 - GPI anchor biosynthetic process
GO:0180041 - dol-P-Man:GlcN-acyl-PI alpha-1,4-mannosyltransferase activity
GO:1990529 - glycosylphosphatidylinositol-mannosyltransferase I complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1432891

SG196
Protein O-mannose kinase

3

0

High-throughput

0.638

High

466969

ACM4
Muscarinic acetylcholine receptor M4

2

1

High-throughput

0.574

High

1316373

AGRG5
Adhesion G-protein coupled receptor G5

2

1

High-throughput

0.574

High

1432893

LT4R2
Leukotriene B4 receptor 2

1

1

High-throughput

0.494

High

641900

DRD4
D(4) dopamine receptor

1

1

High-throughput

0.489

High

688682

NKG2C
NKG2-C type II integral membrane protein

1

1

High-throughput

0.489

High

1059327

NKG2E
NKG2-E type II integral membrane protein

1

1

High-throughput

0.489

High

1360204

5HT3C
5-hydroxytryptamine receptor 3C

3

0

High-throughput

0.347

High

1432894

STAR7
StAR-related lipid transfer protein 7, mitochondrial

3

0

High-throughput

0.342

High

1416620

TM2D2
TM2 domain-containing protein 2

2

0

High-throughput

0.328

High

1396165

CNDP1
Beta-Ala-His dipeptidase

2

0

High-throughput

0.318

High

163165

CHK1
Serine/threonine-protein kinase Chk1

1

0

High-throughput

0.282

High

132661

UPK1A
Uroplakin-1a

1

0

High-throughput

0.279

Low

260799

RAMP2
Receptor activity-modifying protein 2

1

0

High-throughput

0.279

Low

276254

SEM7A
Semaphorin-7A

1

0

High-throughput

0.279

Low

407213

CD3D
T-cell surface glycoprotein CD3 delta chain

1

0

High-throughput

0.279

Low

463222

YES
Tyrosine-protein kinase Yes

1

0

High-throughput

0.279

Low

640465

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

0

High-throughput

0.279

Low

690380

STOM
Stomatin

1

0

High-throughput

0.279

Low

719842

V2R
Vasopressin V2 receptor

1

0

High-throughput

0.279

Low

977829

ACTA
Actin, aortic smooth muscle

1

0

High-throughput

0.279

Low

1339949

OR4N2
Olfactory receptor 4N2

1

0

High-throughput

0.279

Low

1350068

SPP2B
Signal peptide peptidase-like 2B

1

0

High-throughput

0.279

Low

1351529

HAVR2
Hepatitis A virus cellular receptor 2

1

0

High-throughput

0.279

Low

1388188

CKLF5
CKLF-like MARVEL transmembrane domain-containing protein 5

1

0

High-throughput

0.279

Low

1389590

SAAL1
Protein SAAL1

1

0

High-throughput

0.279

Low

1399611

OPALI
Opalin

1

0

High-throughput

0.279

Low

1419565

ABCA2
ATP-binding cassette sub-family A member 2

1

0

High-throughput

0.279

Low

1432413

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.279

Low

1432892

AT133
Polyamine-transporting ATPase 13A3

1

0

High-throughput

0.279

Low

1432895

SC5A4
Probable glucose sensor protein SLC5A4

1

0

High-throughput

0.279

Low

1432896

GGT7
Glutathione hydrolase 7

1

0

High-throughput

0.279

Low

294324

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

1005556

GBRE
Gamma-aminobutyric acid receptor subunit epsilon

1

0

High-throughput

0.249

Low

1042782

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

1

0

High-throughput

0.249

Low

1220795

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low

256150

S19A2
Thiamine transporter 1

1

0

High-throughput

0.232

Low

1236315

MFSD5
Molybdate-anion transporter

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025