Protein: STAC
SH3 and cysteine-rich domain-containing protein (Src homology 3 and cysteine-rich domain-containing protein)

Gene: STAC
Organism: Homo sapiens
Interactions: 37
UniProt ID: Q99469

Gene Ontology (top 5):
GO:0003009 - skeletal muscle contraction
GO:0005829 - cytosol
GO:0007165 - signal transduction
GO:0008270 - zinc ion binding
GO:0009898 - cytoplasmic side of plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

971920

1433E
14-3-3 protein epsilon

3

14

Small-scale

0.886

High

1404631

SPN90
NCK-interacting protein with SH3 domain

3

7

High-throughput

0.853

High

990647

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.789

High

907289

STA5B
Signal transducer and activator of transcription 5B

2

5

High-throughput

0.783

High

1225054

KANK2
KN motif and ankyrin repeat domain-containing protein 2

3

20

High-throughput

0.755

High

1209547

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

11

Small-scale

0.692

High

730181

1433B
14-3-3 protein beta/alpha

1

20

High-throughput

0.691

High

1252014

STAC2
SH3 and cysteine-rich domain-containing protein 2

1

20

High-throughput

0.691

High

1404634

UBQL1
Ubiquilin-1

1

15

High-throughput

0.665

High

1404628

LZTS2
Leucine zipper putative tumor suppressor 2

3

20

High-throughput

0.654

High

1399989

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

17

High-throughput

0.647

High

1293991

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

3

2

High-throughput

0.609

High

685322

PAX6
Paired box protein Pax-6

2

7

High-throughput

0.606

High

1404630

RN208
RING finger protein 208

2

6

High-throughput

0.606

High

1331217

K1958
Uncharacterized protein KIAA1958

3

2

High-throughput

0.597

High

650374

FGFR3
Fibroblast growth factor receptor 3

1

20

High-throughput

0.594

High

1369680

KLK6
Kallikrein-6

1

3

High-throughput

0.594

High

1007977

PO6F2
POU domain, class 6, transcription factor 2

2

19

High-throughput

0.553

High

1037738

PAX5
Paired box protein Pax-5

2

7

High-throughput

0.553

High

1063561

GOGA2
Golgin subfamily A member 2

2

20

High-throughput

0.553

High

386137

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

High-throughput

0.508

High

1151630

TRIP6
Thyroid receptor-interacting protein 6

1

20

High-throughput

0.508

High

1404633

LIMD1
LIM domain-containing protein 1

1

20

High-throughput

0.508

High

422957

A4
Amyloid-beta precursor protein

1

9

High-throughput

0.501

High

1339838

PJA1
E3 ubiquitin-protein ligase Praja-1

1

6

Small-scale

0.501

High

1404632

PARP2
Poly [ADP-ribose] polymerase 2

1

5

Small-scale

0.484

High

1293803

FBX11
F-box only protein 11

1

1

High-throughput

0.479

High

1148464

SAFB1
Scaffold attachment factor B1

1

8

High-throughput

0.470

High

517089

NT2NC
Notch homolog 2 N-terminal-like protein C

1

7

High-throughput

0.470

High

1232536

Q6FHY5
MEOX2 protein

1

11

High-throughput

0.470

High

1289877

Q86V38
Atrophin 1

1

20

High-throughput

0.470

High

1349753

FBX25
F-box only protein 25

1

2

Small-scale

0.457

High

607

NBPFJ
NBPF family member NBPF19

1

20

High-throughput

0.439

High

894112

MEOX2
Homeobox protein MOX-2

1

8

High-throughput

0.439

High

1277366

NT2NA
Notch homolog 2 N-terminal-like protein A

1

7

High-throughput

0.439

High

189793

STX7
Syntaxin-7

1

7

High-throughput

0.437

High

1404629

TRMO
tRNA

1

0

High-throughput

0.265

Low


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Last updated: 11Aug2025