Protein: ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (DLST) (EC 2.3.1.61) (2-oxoglutarate dehydrogenase complex component E2) (OGDC-E2) (OGDHC subunit E2) (Alpha-ketoglutarate dehydrogenase subunit E2) (alpha-KGDHC subunit E2) (Dihydrolipoamide succinyltransferase component of 2-oxoglutarate dehydrogenase complex)

Gene: ODO2, KGD2
Organism: Saccharomyces cerevisiae S288C
Interactions: 108
UniProt ID: P19262

Gene Ontology (top 5):
GO:0004149 - dihydrolipoyllysine-residue succinyltransferase activity
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006099 - tricarboxylic acid cycle
GO:0006103 - 2-oxoglutarate metabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

581261

ODO1
2-oxoglutarate dehydrogenase, mitochondrial

8

13

Small-scale

0.969

High

452951

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

7

12

Small-scale

0.748

High

581260

KGD4
Alpha-ketoglutarate dehydrogenase subunit 4, mitochondrial

5

0

Small-scale

0.691

High

520785

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

14

High-throughput

0.618

High

558554

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, mitochondrial

1

11

High-throughput

0.618

High

477880

HSP77
Import motor subunit, mitochondrial

2

9

High-throughput

0.584

High

581279

HSP78
Heat shock protein 78, mitochondrial

2

3

High-throughput

0.584

High

424335

PYR1
Multifunctional protein URA2

1

5

High-throughput

0.575

High

581276

RSSA1
Small ribosomal subunit protein uS2A

2

1

High-throughput

0.571

High

498430

METK1
S-adenosylmethionine synthase 1

2

0

High-throughput

0.563

High

510205

SSB1
Ribosome-associated molecular chaperone SSB1

2

4

High-throughput

0.552

High

581259

HSP60
Heat shock protein 60, mitochondrial

2

5

High-throughput

0.552

High

581278

UFD4
Ubiquitin fusion degradation protein 4

1

12

High-throughput

0.541

High

581295

IMB4
Importin subunit beta-4

2

3

High-throughput

0.537

High

581317

CLU
Clustered mitochondria protein 1

2

2

High-throughput

0.537

High

534692

RL30
Large ribosomal subunit protein eL30

1

1

High-throughput

0.536

High

581294

RV167
Reduced viability upon starvation protein 167

1

2

High-throughput

0.536

High

581258

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

14

Small-scale

0.527

High

581310

CARME
Carnosine N-methyltransferase

1

0

High-throughput

0.518

High

404490

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.513

High

581323

SHS1
Seventh homolog of septin 1

1

0

High-throughput

0.513

High

523336

SRS2
ATP-dependent DNA helicase SRS2

1

2

High-throughput

0.500

High

581266

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

2

High-throughput

0.500

High

581290

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.500

High

581306

BUD32
EKC/KEOPS complex subunit BUD32

1

1

High-throughput

0.500

High

581313

SLT2
Mitogen-activated protein kinase SLT2/MPK1

1

2

High-throughput

0.500

High

581324

ADY3
Accumulates dyads protein 3

1

10

High-throughput

0.494

High

340011

KPYK1
Pyruvate kinase 1

1

1

High-throughput

0.489

High

389624

DNLI1
DNA ligase 1

1

0

High-throughput

0.479

High

357870

RS17A
Small ribosomal subunit protein eS17A

1

1

High-throughput

0.479

High

405417

RL26A
Large ribosomal subunit protein uL24A

1

1

High-throughput

0.479

High

406764

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

413292

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

425749

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

470850

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

472007

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.479

High

479910

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

482069

RS18A
Small ribosomal subunit protein uS13A

1

1

High-throughput

0.479

High

581267

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

3

High-throughput

0.479

High

581269

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.479

High

581273

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

8

High-throughput

0.479

High

581275

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

1

1

High-throughput

0.479

High

581281

RS3A1
Small ribosomal subunit protein eS1A

1

1

High-throughput

0.479

High

581287

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.479

High

581291

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

581292

TOM71
Protein TOM71

1

4

High-throughput

0.479

High

581293

ILV3
Dihydroxy-acid dehydratase, mitochondrial

1

1

High-throughput

0.479

High

581303

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.479

High

581311

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.479

High

581314

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

581319

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

1

High-throughput

0.479

High

581326

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.479

High

581329

SMC6
Structural maintenance of chromosomes protein 6

1

4

High-throughput

0.479

High

581272

IMB3
Importin subunit beta-3

1

3

High-throughput

0.464

High

581328

SMT3
Ubiquitin-like protein SMT3

1

6

High-throughput

0.464

High

382940

RL25
Large ribosomal subunit protein uL23

1

0

High-throughput

0.458

High

410750

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.458

High

471737

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.458

High

478834

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.458

High

581263

STDH
Catabolic L-serine/threonine dehydratase [Includes: L-serine dehydratase

1

0

High-throughput

0.458

High

581286

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

581299

FIS1
Mitochondrial fission 1 protein

1

0

Small-scale

0.458

High

581305

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

0

High-throughput

0.458

High

581315

GLRX5
Monothiol glutaredoxin-5, mitochondrial

1

0

High-throughput

0.458

High

581321

VIP1
Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase

1

0

High-throughput

0.458

High

429621

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.457

High

539301

KSS1
Mitogen-activated protein kinase KSS1

1

2

High-throughput

0.457

High

581262

DBF2
Cell cycle protein kinase DBF2

1

4

High-throughput

0.457

High

581288

TAF5
Transcription initiation factor TFIID subunit 5

1

8

High-throughput

0.457

High

581289

SIF2
SIR4-interacting protein SIF2

1

3

High-throughput

0.457

High

581297

RAD26
DNA repair and recombination protein RAD26

1

3

High-throughput

0.457

High

581298

PRK1
Actin-regulating kinase PRK1

1

1

High-throughput

0.457

High

581301

YFI6
Uncharacterized protein YFR016C

1

5

High-throughput

0.457

High

581320

UTP13
U3 small nucleolar RNA-associated protein 13

1

5

High-throughput

0.457

High

367720

EF1A
Elongation factor 1-alpha

1

1

High-throughput

0.445

High

490285

HSP71
Heat shock protein SSA1

1

5

High-throughput

0.445

High

493156

HSP72
Heat shock protein SSA2

1

5

High-throughput

0.445

High

543161

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.445

High

581274

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.445

High

581296

SSB2
Ribosome-associated molecular chaperone SSB2

1

4

High-throughput

0.445

High

581265

TAH1
TPR repeat-containing protein associated with Hsp90

1

2

Small-scale

0.437

High

581270

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.437

High

581271

BMH1
Protein BMH1

1

5

High-throughput

0.437

High

581280

IXR1
Intrastrand cross-link recognition protein

1

5

Small-scale

0.437

High

581285

DEF1
RNA polymerase II degradation factor 1

1

3

High-throughput

0.437

High

581308

GIS2
Zinc finger protein GIS2

1

1

High-throughput

0.437

High

581312

ORC1
Origin recognition complex subunit 1

1

2

High-throughput

0.437

High

581316

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.437

High

581318

RUVB1
RuvB-like protein 1

1

2

High-throughput

0.437

High

581304

RL4B
Large ribosomal subunit protein uL4B

1

0

High-throughput

0.426

High

581309

IPI3
Pre-rRNA-processing protein IPI3

1

6

High-throughput

0.417

High

555794

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

581300

MPG1
Mannose-1-phosphate guanyltransferase

1

1

High-throughput

0.407

High

581277

STE5
Protein STE5

1

0

High-throughput

0.269

Low

581302

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.269

Low

541515

AMPL
Vacuolar aminopeptidase 1

1

0

High-throughput

0.261

Low

579925

YPK2
Serine/threonine-protein kinase YPK2/YKR2

1

0

High-throughput

0.261

Low

581282

SIP2
SNF1 protein kinase subunit beta-2

1

0

High-throughput

0.261

Low

581283

PP2C3
Protein phosphatase 2C homolog 3

1

0

High-throughput

0.261

Low

581322

PRP11
Pre-mRNA-splicing factor PRP11

1

0

High-throughput

0.261

Low

581325

RBX1
RING-box protein HRT1

1

0

High-throughput

0.261

Low

581327

RAD59
DNA repair protein RAD59

1

0

High-throughput

0.261

Low

581264

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

581268

SPB4
ATP-dependent rRNA helicase SPB4

1

0

High-throughput

0.249

Low

581284

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

581307

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.249

Low

472631

YL21B
Transposon Ty2-LR1 Gag-Pol polyprotein

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024