Protein: PRP45
Pre-mRNA-processing protein 45

Gene: PRP45
Organism: Saccharomyces cerevisiae S288C
Interactions: 112
UniProt ID: P28004

Gene Ontology (top 5):
GO:0000350 - generation of catalytic spliceosome for second transesterification step
GO:0005634 - nucleus
GO:0071006 - U2-type catalytic step 1 spliceosome
GO:0071007 - U2-type catalytic step 2 spliceosome
GO:0071014 - post-mRNA release spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

655771

CLF1
Pre-mRNA-splicing factor CLF1

5

8

Small-scale

0.921

High

655772

PRP46
Pre-mRNA-splicing factor PRP46

9

5

Small-scale

0.874

High

655717

PRP17
Pre-mRNA-processing factor 17

3

7

High-throughput

0.855

High

655691

PRP8
Pre-mRNA-splicing factor 8

2

3

High-throughput

0.789

High

655748

SYF1
Pre-mRNA-splicing factor SYF1

7

7

Small-scale

0.746

High

655767

CWC2
Pre-mRNA-splicing factor CWC2

6

5

Small-scale

0.735

High

655746

CEF1
Pre-mRNA-splicing factor CEF1

6

2

Small-scale

0.733

High

655683

PRP19
Pre-mRNA-processing factor 19

5

6

Small-scale

0.714

High

655766

RU2A
U2 small nuclear ribonucleoprotein A'

5

2

Small-scale

0.712

High

655679

YJU2
Splicing factor YJU2

4

1

Small-scale

0.683

High

655729

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

3

7

High-throughput

0.671

High

655684

PRP21
Pre-mRNA-splicing factor PRP21

3

1

High-throughput

0.662

High

655698

SN114
Pre-mRNA-splicing factor SNU114

3

3

High-throughput

0.662

High

655725

SF3B1
U2 snRNP component HSH155

3

6

High-throughput

0.662

High

655750

RSE1
Pre-mRNA-splicing factor RSE1

3

3

High-throughput

0.662

High

622297

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

3

8

Small-scale

0.647

High

629359

BUD31
Pre-mRNA-splicing factor BUD31

1

2

High-throughput

0.618

High

655687

BRR2
Pre-mRNA-splicing helicase BRR2

2

10

High-throughput

0.611

High

655762

PRP11
Pre-mRNA-splicing factor PRP11

2

1

High-throughput

0.601

High

655758

SP382
Pre-mRNA-splicing factor SPP382

2

0

Small-scale

0.596

High

655724

MDV1
Mitochondrial division protein 1

1

5

High-throughput

0.587

High

655773

EAF3
Chromatin modification-related protein EAF3

2

1

Small-scale

0.586

High

655731

SYF2
Pre-mRNA-splicing factor SYF2

1

0

High-throughput

0.586

High

655747

CWC15
Pre-mRNA-splicing factor CWC15

1

0

High-throughput

0.586

High

655752

SN309
Pre-mRNA-splicing factor SNT309

2

0

High-throughput

0.585

High

589414

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

2

8

High-throughput

0.584

High

655695

NCBP1
Nuclear cap-binding protein complex subunit 1

2

1

High-throughput

0.584

High

655711

RSMB
Small nuclear ribonucleoprotein-associated protein B

2

1

High-throughput

0.584

High

655727

CWC23
Pre-mRNA-splicing factor CWC23

2

1

High-throughput

0.567

High

655757

ATG17
Autophagy-related protein 17

2

0

High-throughput

0.565

High

655680

XPO1
Exportin-1

1

1

High-throughput

0.536

High

655759

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.513

High

655739

ADA2
Transcriptional adapter 2

1

3

High-throughput

0.508

High

571879

SKI3
Superkiller protein 3

1

4

Small-scale

0.481

High

623437

KPC1
Protein kinase C-like 1

1

2

Small-scale

0.481

High

655681

RAD16
DNA repair protein RAD16

1

9

Small-scale

0.481

High

655694

NIP80
Protein NIP100

1

3

High-throughput

0.481

High

655696

SGS1
ATP-dependent helicase SGS1

1

5

Small-scale

0.481

High

655714

ATAD2
ATPase histone chaperone YTA7

1

2

Small-scale

0.481

High

655734

VPS75
Vacuolar protein sorting-associated protein 75

1

1

Small-scale

0.481

High

554203

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

8

High-throughput

0.479

High

586463

PRP9
Pre-mRNA-splicing factor PRP9

1

1

High-throughput

0.479

High

598612

ISY1
Pre-mRNA-splicing factor ISY1

1

2

High-throughput

0.479

High

655704

SLT11
Pre-mRNA-splicing factor SLT11

1

2

High-throughput

0.479

High

655713

RUXG
Small nuclear ribonucleoprotein G

1

2

High-throughput

0.479

High

655716

IST3
U2 snRNP component IST3

1

4

High-throughput

0.479

High

655720

SMD3
Small nuclear ribonucleoprotein Sm D3

1

4

High-throughput

0.479

High

655737

RUXF
Small nuclear ribonucleoprotein F

1

1

High-throughput

0.479

High

655741

CUS1
Cold sensitive U2 snRNA suppressor 1

1

1

High-throughput

0.479

High

655765

NCBP2
Nuclear cap-binding protein subunit 2

1

3

High-throughput

0.479

High

655769

SCC1
Sister chromatid cohesion protein 1

1

1

High-throughput

0.479

High

655775

HSH49
Protein HSH49

1

4

High-throughput

0.479

High

343178

TRP
Tryptophan synthase

1

0

Small-scale

0.460

High

655682

NGG1
Chromatin-remodeling complexes subunit NGG1

1

0

Small-scale

0.460

High

655690

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

655719

GSM1
Glucose starvation modulator protein 1

1

0

Small-scale

0.460

High

655730

ENV11
Late endosome and vacuole interface protein 11

1

0

Small-scale

0.460

High

655736

NIS1
Protein NIS1

1

0

Small-scale

0.460

High

655743

ECM5
Protein ECM5

1

0

Small-scale

0.460

High

655754

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

Small-scale

0.460

High

655770

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

Small-scale

0.460

High

655774

AHC1
Protein AHC1

1

0

Small-scale

0.460

High

605927

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

655686

RU1A
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.458

High

655699

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

655700

YK21
Uncharacterized protein YKR041W

1

0

High-throughput

0.458

High

655705

NTC20
Pre-mRNA-splicing factor NTC20

1

0

High-throughput

0.458

High

655707

WSS1
DNA-dependent metalloprotease WSS1

1

0

Small-scale

0.458

High

655721

CWC26
Pre-mRNA-splicing factor CWC26

1

0

High-throughput

0.458

High

655738

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

655742

SLU7
Pre-mRNA-splicing factor SLU7

1

0

High-throughput

0.458

High

655755

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

655761

RDS3
Pre-mRNA-splicing factor RDS3

1

0

High-throughput

0.458

High

655702

IMB2
Importin subunit beta-2

1

4

High-throughput

0.457

High

365910

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.445

High

376667

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

2

High-throughput

0.445

High

493364

HSP72
Heat shock protein SSA2

1

3

High-throughput

0.445

High

655685

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

647435

AP2B
AP-2 complex subunit beta

1

4

Small-scale

0.439

High

655688

SEC6
Exocyst complex component SEC6

1

1

Small-scale

0.439

High

655692

SLA2
Protein SLA2

1

6

Small-scale

0.439

High

655697

DYHC
Dynein heavy chain, cytoplasmic

1

2

Small-scale

0.439

High

655701

CDC27
Anaphase-promoting complex subunit CDC27

1

4

Small-scale

0.439

High

655708

AP18A
Clathrin coat assembly protein AP180A

1

5

Small-scale

0.439

High

655718

BNI1
Protein BNI1

1

3

Small-scale

0.439

High

655751

EIS1
Eisosome protein 1

1

1

Small-scale

0.439

High

655722

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.438

High

655764

SOG2
Leucine-rich repeat-containing protein SOG2

1

3

High-throughput

0.417

High

655710

TCPG
T-complex protein 1 subunit gamma

1

5

High-throughput

0.407

High

655732

CWC22
Pre-mRNA-splicing factor CWC22

3

0

High-throughput

0.345

High

655753

YL345
Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W [Includes: 6-phosphofructo-2-kinase

3

0

High-throughput

0.337

High

655744

CWC21
Pre-mRNA-splicing factor CWC21

2

0

Small-scale

0.305

High

655706

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.279

Low

613103

URE2
Transcriptional regulator URE2

1

0

High-throughput

0.265

Low

655749

KRE28
Spindle pole body component KRE28

1

0

High-throughput

0.265

Low

655703

FL2D
Protein MUM2

1

0

High-throughput

0.251

Low

655709

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

Small-scale

0.251

Low

655712

FIR1
Factor interacting with REF2

1

0

Small-scale

0.251

Low

655715

YJ31
Uncharacterized protein YJR061W

1

0

Small-scale

0.251

Low

655723

DAS1
F-box protein DAS1

1

0

Small-scale

0.251

Low

655726

NU188
Nucleoporin NUP188

1

0

Small-scale

0.251

Low

655728

NUP84
Nucleoporin NUP84

1

0

Small-scale

0.251

Low

655733

MNT4
Probable alpha-1,3-mannosyltransferase MNT4

1

0

Small-scale

0.251

Low

655745

RMD1
Sporulation protein RMD1

1

0

Small-scale

0.251

Low

655756

SKG3
Protein SKG3

1

0

Small-scale

0.251

Low

655760

VAC14
Vacuole morphology and inheritance protein 14

1

0

Small-scale

0.251

Low

655763

UBR2
E3 ubiquitin-protein ligase UBR2

1

0

Small-scale

0.251

Low

655735

CWC25
Pre-mRNA-splicing factor CWC25

1

0

High-throughput

0.249

Low

655740

SPP2
Pre-mRNA-splicing factor SPP2

1

0

High-throughput

0.249

Low

655768

YG11A
Transposon Ty1-GR1 Gag polyprotein

1

0

High-throughput

0.249

Low

655689

PEP12
Syntaxin PEP12

1

0

High-throughput

0.238

Low

655693

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024