Protein: SUM1
Suppressor of mar1-1 protein (SUM1-1 protein)

Gene: SUM1
Organism: Saccharomyces cerevisiae S288C
Interactions: 72
UniProt ID: P46676

Gene Ontology (top 5):
GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000278 - mitotic cell cycle
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

858413

HST1
NAD-dependent protein deacetylase HST1

6

1

Small-scale

0.729

High

858425

RFM1
Repression factor of MSEs protein 1

4

0

Small-scale

0.658

High

826612

DSN1
Kinetochore-associated protein DSN1

2

0

High-throughput

0.559

High

858408

SUM1
Suppressor of mar1-1 protein

2

0

Small-scale

0.559

High

858410

ORC5
Origin recognition complex subunit 5

2

0

Small-scale

0.559

High

527010

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

858415

H3
Histone H3

2

0

High-throughput

0.547

High

792851

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.530

High

545339

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

602128

SPO12
Sporulation-specific protein 12

1

0

High-throughput

0.513

High

740587

IME2
Meiosis induction protein kinase IME2/SME1

1

0

Small-scale

0.480

High

381550

H2B2
Histone H2B.2

1

1

High-throughput

0.479

High

444777

SIR2
NAD-dependent histone deacetylase SIR2

1

1

Small-scale

0.479

High

550667

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.460

High

749685

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

858411

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.460

High

382180

H4
Histone H4

1

0

High-throughput

0.458

High

419786

H2A2
Histone H2A.2

1

0

High-throughput

0.458

High

585503

KCY
Uridylate kinase

1

0

High-throughput

0.458

High

594436

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

627800

PYRC
Dihydroorotase

1

0

High-throughput

0.458

High

646448

RAD53
Serine/threonine-protein kinase RAD53

1

0

High-throughput

0.458

High

647795

RFA1
Replication factor A protein 1

1

0

Small-scale

0.458

High

707461

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

745653

ORC2
Origin recognition complex subunit 2

1

0

Small-scale

0.458

High

745793

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

763930

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

805552

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

0

Small-scale

0.458

High

808847

UME6
Transcriptional regulatory protein UME6

1

0

High-throughput

0.458

High

858409

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

858414

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

858418

RUVB1
RuvB-like protein 1

1

0

High-throughput

0.458

High

858419

SIZ1
E3 SUMO-protein ligase SIZ1

1

0

High-throughput

0.458

High

858420

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

858422

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.458

High

858423

SGO1
Shugoshin

1

0

High-throughput

0.458

High

858424

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

858429

CMR1
DNA damage-binding protein CMR1

1

0

High-throughput

0.458

High

381150

H2B1
Histone H2B.1

1

1

High-throughput

0.445

High

524352

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

670867

SIS1
Protein SIS1

1

1

High-throughput

0.445

High

741839

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

781758

SET3
SET domain-containing protein 3

1

1

High-throughput

0.445

High

811343

CAJ1
Protein CAJ1

1

1

High-throughput

0.445

High

858421

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

762920

CYPD
Peptidyl-prolyl cis-trans isomerase D

1

1

High-throughput

0.437

High

392943

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.426

High

548780

MCM1
Pheromone receptor transcription factor

1

0

High-throughput

0.426

High

649983

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

676110

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.426

High

736670

ASF1
Histone chaperone ASF1

1

0

High-throughput

0.426

High

738754

CBF3A
Centromere DNA-binding protein complex CBF3 subunit A

1

0

High-throughput

0.426

High

822996

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.426

High

858417

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.426

High

858428

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.426

High

858416

RSC4
Chromatin structure-remodeling complex subunit RSC4

1

1

High-throughput

0.407

High

850437

LSB3
LAS seventeen-binding protein 3

1

0

High-throughput

0.282

High

802517

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.251

Low

858412

MPS2
Monopolar spindle protein 2

1

0

High-throughput

0.251

Low

360998

CCPR
Cytochrome c peroxidase, mitochondrial

1

0

High-throughput

0.249

Low

432621

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.249

Low

680600

CYPC
Peptidyl-prolyl cis-trans isomerase C, mitochondrial

1

0

High-throughput

0.249

Low

793052

PDX3
Pyridoxamine 5'-phosphate oxidase

1

0

High-throughput

0.249

Low

793614

ARA1
D-arabinose dehydrogenase [NAD(P)+] heavy chain

1

0

High-throughput

0.249

Low

794831

KMO
Kynurenine 3-monooxygenase

1

0

High-throughput

0.249

Low

797755

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

815794

GDI1
Rab GDP-dissociation inhibitor

1

0

High-throughput

0.249

Low

858426

DBP10
ATP-dependent RNA helicase DBP10

1

0

High-throughput

0.249

Low

858427

MPC70
Sporulation-specific protein 21

1

0

High-throughput

0.249

Low

815001

SLN1
Osmosensing histidine protein kinase SLN1

1

0

High-throughput

0.232

Low

858376

STU2
Protein STU2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025