Protein: FCP1
RNA polymerase II subunit A C-terminal domain phosphatase (EC 3.1.3.16) (CTD phosphatase FCP1)

Gene: FCP1
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: Q03254

Gene Ontology (top 5):
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0008420 - RNA polymerase II CTD heptapeptide repeat phosphatase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

402102

RPB1
DNA-directed RNA polymerase II subunit RPB1

5

8

Small-scale

0.708

High

594535

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

3

Small-scale

0.640

High

836535

T2FA
Transcription initiation factor IIF subunit alpha

3

0

Small-scale

0.636

High

708005

TF2B
Transcription initiation factor IIB

2

2

Small-scale

0.595

High

393230

HSP82
ATP-dependent molecular chaperone HSP82

1

2

High-throughput

0.541

High

921607

NRD1
Protein NRD1

1

0

Small-scale

0.494

High

617867

DDR48
Stress protein DDR48

1

0

High-throughput

0.493

High

1042113

CSN10
COP9 signalosome complex subunit 10

1

0

High-throughput

0.493

High

364714

CDK1
Cyclin-dependent kinase 1

1

1

High-throughput

0.481

High

755286

NUF2
Kinetochore protein NUF2

1

2

High-throughput

0.481

High

806872

SKN7
Transcription factor SKN7

1

1

High-throughput

0.481

High

812607

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.481

High

829790

MAD1
Spindle assembly checkpoint component MAD1

1

5

High-throughput

0.481

High

864673

SNX4
Sorting nexin-4

1

1

High-throughput

0.481

High

1042109

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.481

High

1042110

VPS20
Vacuolar protein sorting-associated protein 20

1

3

High-throughput

0.481

High

632108

RPB4
DNA-directed RNA polymerase II subunit RPB4

1

3

Small-scale

0.479

High

460360

SYV
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.460

High

864691

VPS53
Vacuolar protein sorting-associated protein 53

1

0

High-throughput

0.460

High

865846

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.460

High

910768

SKP1
Suppressor of kinetochore protein 1

1

0

High-throughput

0.460

High

1031763

CIK1
Spindle pole body-associated protein CIK1

1

0

High-throughput

0.460

High

1038150

CENPP
Inner kinetochore subunit CTF19

1

0

High-throughput

0.460

High

735133

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

926004

SUB1
RNA polymerase II transcriptional coactivator SUB1

1

0

Small-scale

0.458

High

678791

PDP2
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 2, mitochondrial

1

2

High-throughput

0.457

High

367105

ATPB
ATP synthase subunit beta, mitochondrial

1

1

High-throughput

0.445

High

486510

TBA3
Tubulin alpha-3 chain

1

8

High-throughput

0.445

High

546050

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.445

High

739450

ZUO1
Zuotin

1

5

High-throughput

0.445

High

806054

KEL1
Kelch repeat-containing protein 1

1

2

High-throughput

0.439

High

1042112

DSC3
DSC E3 ubiquitin ligase complex subunit 3

1

1

High-throughput

0.439

High

624799

PMA2
Plasma membrane ATPase 2

1

6

High-throughput

0.437

High

704699

PRR1
Serine/threonine-protein kinase PRR1

1

3

High-throughput

0.437

High

1036913

MLP1
Protein MLP1

1

6

High-throughput

0.437

High

394852

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

858054

RSSA2
Small ribosomal subunit protein uS2B

1

0

High-throughput

0.426

High

1035051

UBC7
Ubiquitin-conjugating enzyme E2 7

1

2

High-throughput

0.417

High

592461

VATB
V-type proton ATPase subunit B

1

1

High-throughput

0.407

High

813843

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.251

Low

627765

TYR1
Prephenate dehydrogenase [NADP(+)]

1

0

Small-scale

0.249

Low

1042111

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.249

Low

365169

KPYK1
Pyruvate kinase 1

1

0

High-throughput

0.232

Low

575509

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

0

High-throughput

0.232

Low

836866

MPG1
Mannose-1-phosphate guanyltransferase

1

0

High-throughput

0.232

Low

849550

GCN20
Protein GCN20

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025