Protein: MLC1
Myosin light chain 1 (Calmodulin-like myosin light chain MLC1) (Myosin-2 light chain)

Gene: MLC1
Organism: Saccharomyces cerevisiae S288C
Interactions: 115
UniProt ID: P53141

Gene Ontology (top 5):
GO:0000142 - cellular bud neck contractile ring
GO:0000920 - septum digestion after cytokinesis
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane
GO:0005934 - cellular bud tip

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

623904

MYO2
Myosin-2

13

16

Small-scale

0.981

High

917647

IQG1
Ras GTPase-activating-like protein IQG1

8

20

Small-scale

0.970

High

477597

MYO1
Myosin-1

7

15

Small-scale

0.962

High

738105

MYO4
Myosin-4

4

19

High-throughput

0.896

High

449153

CALM
Calmodulin

3

14

High-throughput

0.867

High

917614

MLC1
Myosin light chain 1

2

15

Small-scale

0.775

High

748876

SWE1
Mitosis inhibitor protein kinase SWE1

1

4

High-throughput

0.691

High

797218

SHE3
SWI5-dependent HO expression protein 3

5

0

High-throughput

0.688

High

917628

STE20
Serine/threonine-protein kinase STE20

1

3

High-throughput

0.621

High

917621

MPS1
Serine/threonine-protein kinase MPS1

1

5

High-throughput

0.618

High

671970

HAL4
Serine/threonine-protein kinase HAL4/SAT4

1

11

High-throughput

0.595

High

835511

BUB1
Spindle assembly checkpoint serine/threonine-protein kinase BUB1

1

15

High-throughput

0.595

High

670302

NAP1
Nucleosome assembly protein

2

1

High-throughput

0.576

High

917623

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

1

High-throughput

0.567

High

811523

PIK1
Phosphatidylinositol 4-kinase PIK1

1

4

Small-scale

0.555

High

917627

TOM1
E3 ubiquitin-protein ligase TOM1

2

9

High-throughput

0.549

High

917648

HSP42
Heat shock protein 42

2

1

High-throughput

0.537

High

917632

CYK2
Cytokinesis protein 2

1

1

Small-scale

0.516

High

811272

RGA1
Rho-type GTPase-activating protein 1

1

10

High-throughput

0.515

High

814236

RV167
Reduced viability upon starvation protein 167

1

6

High-throughput

0.515

High

917615

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.515

High

917636

MLC2
Myosin light chain 2

1

20

High-throughput

0.515

High

917646

LSP1
Sphingolipid long chain base-responsive protein LSP1

1

1

High-throughput

0.515

High

737417

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

5

High-throughput

0.514

High

762893

TREB
Probable trehalase

1

0

High-throughput

0.493

High

835541

BUD6
Bud site selection protein 6

1

0

High-throughput

0.493

High

917637

BSP1
F-actin capping regulator BSP1

1

0

High-throughput

0.493

High

713286

MCM5
Minichromosome maintenance protein 5

1

1

High-throughput

0.489

High

836302

BNI1
Protein BNI1

1

4

Small-scale

0.481

High

458593

SEC4
Ras-related protein SEC4

1

2

Small-scale

0.479

High

579768

HSC82
ATP-dependent molecular chaperone HSC82

1

4

High-throughput

0.479

High

917622

NUM1
Nuclear migration protein NUM1

1

15

High-throughput

0.479

High

453974

IF4E
Eukaryotic translation initiation factor 4E

1

1

High-throughput

0.470

High

622382

ACON
Aconitate hydratase, mitochondrial

1

1

High-throughput

0.470

High

632707

DBP4
ATP-dependent RNA helicase HCA4

1

3

High-throughput

0.470

High

734293

PYC2
Pyruvate carboxylase 2

1

1

High-throughput

0.470

High

744003

RAD23
UV excision repair protein RAD23

1

1

High-throughput

0.470

High

796402

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

2

High-throughput

0.470

High

796603

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

11

High-throughput

0.470

High

893278

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

6

High-throughput

0.470

High

917633

CORO
Coronin-like protein

1

3

High-throughput

0.470

High

94574

STE2
Pheromone alpha factor receptor

1

0

High-throughput

0.460

High

818526

PEA2
Protein PEA2

1

0

Small-scale

0.460

High

917649

GDIR
Rho GDP-dissociation inhibitor

1

0

High-throughput

0.460

High

524617

HSP71
Heat shock protein SSA1

1

4

High-throughput

0.445

High

527228

HSP72
Heat shock protein SSA2

1

4

High-throughput

0.445

High

545632

SSB1
Ribosome-associated molecular chaperone SSB1

1

3

High-throughput

0.445

High

819315

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

865924

BUD4
Bud site selection protein 4

1

0

Small-scale

0.438

High

435237

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

442019

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

503147

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

682342

SPB4
ATP-dependent rRNA helicase SPB4

1

3

High-throughput

0.437

High

689562

RS7A
Small ribosomal subunit protein eS7A

1

1

High-throughput

0.437

High

707698

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

708765

TF3B
Transcription factor IIIB 70 kDa subunit

1

1

High-throughput

0.437

High

748473

SC61A
Protein transport protein SEC61

1

1

High-throughput

0.437

High

778439

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.437

High

802282

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

874426

RS12
Small ribosomal subunit protein eS12

1

1

High-throughput

0.437

High

917617

GIS2
Zinc finger protein GIS2

1

3

High-throughput

0.437

High

917639

VAM6
Vacuolar morphogenesis protein 6

1

1

High-throughput

0.437

High

917642

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.437

High

917643

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.437

High

917644

RRP6
Exosome complex exonuclease RRP6

1

1

High-throughput

0.437

High

917650

LAS17
Proline-rich protein LAS17

1

6

Small-scale

0.437

High

575976

CYPH
Peptidyl-prolyl cis-trans isomerase

1

4

High-throughput

0.407

High

676185

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.407

High

742020

HSP7F
Heat shock protein homolog SSE1

1

6

High-throughput

0.407

High

742901

HSP79
Heat shock protein homolog SSE2

1

6

High-throughput

0.407

High

779559

LHS1
Heat shock protein 70 homolog LHS1

1

5

High-throughput

0.407

High

816317

HSP7E
Heat shock protein SSC3, mitochondrial

1

6

High-throughput

0.407

High

917638

BRE1
E3 ubiquitin-protein ligase BRE1

1

17

High-throughput

0.407

High

917616

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.279

Low

370475

ATIF
F(1)-ATPase inhibitor IF(1), mitochondrial

1

0

High-throughput

0.269

Low

617862

DDR48
Stress protein DDR48

1

0

High-throughput

0.269

Low

734565

MSS51
Protein MSS51, mitochondrial

1

0

High-throughput

0.269

Low

734841

SSH4
Protein SSH4

1

0

High-throughput

0.269

Low

738407

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.269

Low

780378

ELF1
Transcription elongation factor 1

1

0

High-throughput

0.269

Low

795110

NU170
Nucleoporin NUP170

1

0

High-throughput

0.269

Low

796223

RKM3
Ribosomal lysine N-methyltransferase 3

1

0

High-throughput

0.269

Low

814144

SAW1
Single-strand annealing weakened protein 1

1

0

High-throughput

0.269

Low

873842

SYIM
Isoleucine--tRNA ligase, mitochondrial

1

0

High-throughput

0.269

Low

874364

RAD17
DNA damage checkpoint control protein RAD17

1

0

High-throughput

0.269

Low

903547

SHE4
SWI5-dependent HO expression protein 4

1

0

High-throughput

0.269

Low

917620

FAP1
FKBP12-associated protein 1

1

0

High-throughput

0.269

Low

917625

TOF2
Topoisomerase 1-associated factor 2

1

0

High-throughput

0.269

Low

917626

MEC3
DNA damage checkpoint control protein MEC3

1

0

High-throughput

0.269

Low

917629

SRC1
Inner nuclear membrane protein SRC1

1

0

High-throughput

0.269

Low

917630

RAD33
DNA repair protein RAD33

1

0

High-throughput

0.269

Low

917631

TVP18
Golgi apparatus membrane protein TVP18

1

0

High-throughput

0.269

Low

917634

ATG33
Autophagy-related protein 33

1

0

High-throughput

0.269

Low

917641

APC5
Anaphase-promoting complex subunit 5

1

0

High-throughput

0.269

Low

917645

ENG2
Glucan endo-1,3-beta-D-glucosidase 2

1

0

High-throughput

0.269

Low

917651

KCS1
Inositol hexakisphosphate kinase 1

1

0

High-throughput

0.269

Low

917652

YO098
Uncharacterized protein YOL098C

1

0

High-throughput

0.269

Low

402062

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

0

High-throughput

0.249

Low

436067

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

455166

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

513120

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

553635

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

Small-scale

0.249

Low

677489

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

753481

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

764121

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

797765

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

812498

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

871518

HGH1
Protein HGH1

1

0

Small-scale

0.249

Low

917619

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.249

Low

917624

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

917635

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

917640

AB140
tRNA(Thr)

1

0

High-throughput

0.249

Low

917618

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.238

Low

806889

SET5
Histone-lysine N-methyltransferase SET5

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025