Protein: SP381
Pre-mRNA-splicing factor SPP381 (Suppressor of PRP38-1 mutation)

Gene: SP381, SPP381
Organism: Saccharomyces cerevisiae S288C
Interactions: 46
UniProt ID: P38282

Gene Ontology (top 5):
GO:0000349 - generation of catalytic spliceosome for first transesterification step
GO:0000398 - mRNA splicing, via spliceosome
GO:0003723 - RNA binding
GO:0005634 - nucleus
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

747718

PRP38
Pre-mRNA-splicing factor 38

7

0

Small-scale

0.717

High

747730

SNU23
23 kDa U4/U6.U5 small nuclear ribonucleoprotein component

5

0

Small-scale

0.686

High

747708

RSMB
Small nuclear ribonucleoprotein-associated protein B

5

0

High-throughput

0.684

High

697204

BRR2
Pre-mRNA-splicing helicase BRR2

5

0

Small-scale

0.682

High

747731

SNU66
66 kDa U4/U6.U5 small nuclear ribonucleoprotein component

4

0

Small-scale

0.661

High

586399

PRP6
Pre-mRNA-splicing factor 6

3

0

High-throughput

0.634

High

589076

PRP4
U4/U6 small nuclear ribonucleoprotein PRP4

3

0

High-throughput

0.634

High

731724

SN114
Pre-mRNA-splicing factor SNU114

3

0

High-throughput

0.634

High

747714

PRP31
Pre-mRNA-processing factor 31

3

0

High-throughput

0.634

High

747721

PRP3
U4/U6 small nuclear ribonucleoprotein PRP3

3

0

High-throughput

0.634

High

747729

RU2A
U2 small nuclear ribonucleoprotein A'

3

0

High-throughput

0.634

High

586487

PRP9
Pre-mRNA-splicing factor PRP9

2

0

High-throughput

0.595

High

692396

PRP21
Pre-mRNA-splicing factor PRP21

2

0

High-throughput

0.595

High

747710

MSL1
U2 small nuclear ribonucleoprotein B''

2

0

High-throughput

0.595

High

747715

SF3B1
U2 snRNP component HSH155

2

0

High-throughput

0.595

High

747720

CUS1
Cold sensitive U2 snRNA suppressor 1

2

0

High-throughput

0.595

High

747723

RSE1
Pre-mRNA-splicing factor RSE1

2

0

High-throughput

0.595

High

747727

PRP11
Pre-mRNA-splicing factor PRP11

2

0

High-throughput

0.595

High

704660

PRP8
Pre-mRNA-splicing factor 8

2

0

High-throughput

0.585

High

491038

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.552

High

493811

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.552

High

511103

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.528

High

676005

XPO1
Exportin-1

1

0

High-throughput

0.513

High

743509

HMT1
Protein arginine N-methyltransferase 1

1

0

Small-scale

0.480

High

747713

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

1

High-throughput

0.479

High

702659

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

710756

CASP
Protein CASP

1

0

High-throughput

0.460

High

747711

GZF3
Protein GZF3

1

0

High-throughput

0.460

High

747725

HDA2
HDA1 complex subunit 2

1

0

High-throughput

0.460

High

662065

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

733060

NTR2
Pre-mRNA-splicing factor NTR2

1

0

High-throughput

0.458

High

747709

RUXG
Small nuclear ribonucleoprotein G

1

0

High-throughput

0.458

High

747712

SMD3
Small nuclear ribonucleoprotein Sm D3

1

0

High-throughput

0.458

High

747716

PNC1
Nicotinamidase

1

0

High-throughput

0.458

High

747717

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.458

High

747719

SMD1
Small nuclear ribonucleoprotein Sm D1

1

0

High-throughput

0.458

High

747724

SMD2
Small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

747726

DIB1
Spliceosomal protein DIB1

1

0

High-throughput

0.458

High

747728

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.458

High

694586

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

356435

H4
Histone H4

1

0

High-throughput

0.426

High

627974

SIS1
Protein SIS1

1

0

High-throughput

0.426

High

692289

PRP19
Pre-mRNA-processing factor 19

1

0

Small-scale

0.426

High

524273

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

699780

KPR1
Ribose-phosphate pyrophosphokinase 1

1

0

High-throughput

0.249

Low

747722

YD239
Uncharacterized protein YDR239C

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024