Protein: IPI1
Pre-rRNA-processing protein IPI1 (Involved in processing IST2 protein 1)

Gene: IPI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 77
UniProt ID: P38803

Gene Ontology (top 5):
GO:0000027 - ribosomal large subunit assembly
GO:0000463 - maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

804985

RIX1
Pre-rRNA-processing protein RIX1

14

0

Small-scale

0.728

High

805006

IPI3
Pre-rRNA-processing protein IPI3

5

4

High-throughput

0.716

High

805005

NOG2
Nucleolar GTP-binding protein 2

5

2

Small-scale

0.709

High

805021

MDN1
Midasin

4

1

Small-scale

0.689

High

804993

RLP7
Ribosome biogenesis protein RLP7

3

1

High-throughput

0.656

High

805010

NOG1
Nucleolar GTP-binding protein 1

3

1

Small-scale

0.656

High

673561

NLE1
Ribosome assembly protein 4

3

2

Small-scale

0.640

High

805018

BUD20
Bud site selection protein 20

3

0

High-throughput

0.638

High

803857

CIC1
Proteasome-interacting protein CIC1

3

0

High-throughput

0.628

High

805011

ARX1
Probable metalloprotease ARX1

3

0

Small-scale

0.628

High

805002

PESC
Pescadillo homolog

3

0

High-throughput

0.613

High

432571

RL7A
Large ribosomal subunit protein uL30A

2

1

High-throughput

0.611

High

805003

SDA1
Protein SDA1

3

0

Small-scale

0.606

High

511193

RL20B
Large ribosomal subunit protein eL20B

2

1

High-throughput

0.584

High

544791

SSB1
Ribosome-associated molecular chaperone SSB1

2

0

High-throughput

0.576

High

682273

SPB4
ATP-dependent rRNA helicase SPB4

2

0

High-throughput

0.559

High

782326

RPF2
Ribosome biogenesis protein RPF2

2

0

Small-scale

0.559

High

805022

NOP53
Ribosome biogenesis protein NOP53

2

0

High-throughput

0.559

High

684716

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

805009

RL6A
Large ribosomal subunit protein eL6A

1

0

High-throughput

0.513

High

570006

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.479

High

674610

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

677198

SPB1
27S pre-rRNA

1

1

High-throughput

0.479

High

750077

MRT4
Ribosome assembly factor MRT4

1

1

High-throughput

0.479

High

804987

NUG1
Nuclear GTP-binding protein NUG1

1

2

High-throughput

0.479

High

805007

NOP15
Ribosome biogenesis protein 15

1

1

High-throughput

0.479

High

805019

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

435076

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

435950

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

436404

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

503030

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.458

High

512997

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.458

High

513681

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.458

High

514627

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

579346

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

707030

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

795814

YBC8
UPF0642 protein YBL028C

1

0

High-throughput

0.458

High

798210

ENP1
Essential nuclear protein 1

1

0

High-throughput

0.458

High

804983

IPI1
Pre-rRNA-processing protein IPI1

1

0

High-throughput

0.458

High

804986

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.458

High

804989

NSA2
Ribosome biogenesis protein NSA2

1

0

High-throughput

0.458

High

804991

BMT5
25S rRNA

1

0

High-throughput

0.458

High

804995

ALB1
Ribosome biogenesis protein ALB1

1

0

High-throughput

0.458

High

804996

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.458

High

804998

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

804999

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.458

High

805001

CGR1
rRNA-processing protein CGR1

1

0

High-throughput

0.458

High

805008

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

805012

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

805013

NOC4
Nucleolar complex protein 4

1

0

High-throughput

0.458

High

805020

RRS1
Regulator of ribosome biosynthesis

1

0

High-throughput

0.458

High

805023

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

805026

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

779843

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

1

High-throughput

0.457

High

523868

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

526631

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

727006

HS104
Heat shock protein 104

1

1

High-throughput

0.445

High

805000

LSG1
Large subunit GTPase 1

1

2

Small-scale

0.445

High

804984

PEX18
Peroxisomal membrane protein PEX18

1

0

High-throughput

0.438

High

804997

CTH1
mRNA decay factor CTH1

1

0

High-throughput

0.438

High

805014

RSC3
Chromatin structure-remodeling complex protein RSC3

1

0

High-throughput

0.438

High

805024

SIZ2
E3 SUMO-protein ligase SIZ2

1

0

High-throughput

0.438

High

394531

EF1A
Elongation factor 1-alpha

1

0

High-throughput

0.426

High

453585

PYR1
Multifunctional protein URA2

1

0

High-throughput

0.426

High

804994

RL17B
Large ribosomal subunit protein uL22B

1

0

High-throughput

0.426

High

805016

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

0

High-throughput

0.426

High

752230

HSP78
Heat shock protein 78, mitochondrial

1

1

High-throughput

0.407

High

671325

CANB
Calcineurin subunit B

1

0

High-throughput

0.249

Low

745078

AFG2
ATPase family gene 2 protein

1

0

High-throughput

0.249

Low

805017

RLP24
Ribosome biogenesis protein RLP24

1

0

High-throughput

0.249

Low

804988

SERA
D-3-phosphoglycerate dehydrogenase 1

1

0

High-throughput

0.238

Low

804990

YE17
Uncharacterized protein YER187W

1

0

High-throughput

0.238

Low

804992

GST1
Glutathione S-transferase 1

1

0

High-throughput

0.238

Low

805004

ZNG1
Zinc-regulated GTPase metalloprotein activator 1

1

0

High-throughput

0.238

Low

805015

OMS1
Methyltransferase OMS1, mitochondrial

1

0

High-throughput

0.238

Low

805025

HSP42
Heat shock protein 42

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025