Protein: PSB5
Proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit PRE2) (Multicatalytic endopeptidase complex subunit PRE2) (Proteasome component PRE2) (Proteinase YSCE subunit PRE2)

Gene: PSB5, PRE2
Organism: Saccharomyces cerevisiae S288C
Interactions: 80
UniProt ID: P30656

Gene Ontology (top 5):
GO:0000502 - proteasome complex
GO:0004175 - endopeptidase activity
GO:0004298 - threonine-type endopeptidase activity
GO:0005634 - nucleus
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

604764

PSB4
Proteasome subunit beta type-4

17

20

Small-scale

0.984

High

675413

PSB1
Proteasome subunit beta type-1

8

20

Small-scale

0.966

High

597211

PSA7
Probable proteasome subunit alpha type-7

8

20

Small-scale

0.963

High

675422

PSA4
Proteasome subunit alpha type-4

8

20

Small-scale

0.963

High

597296

PSA1
Proteasome subunit alpha type-1

7

20

Small-scale

0.962

High

632470

PSB3
Proteasome subunit beta type-3

7

20

Small-scale

0.960

High

619422

PSA2
Proteasome subunit alpha type-2

8

20

Small-scale

0.960

High

619335

PSA3
Proteasome subunit alpha type-3

7

20

Small-scale

0.958

High

675421

PSA6
Proteasome subunit alpha type-6

7

20

Small-scale

0.958

High

675396

PSB7
Proteasome subunit beta type-7

7

20

Small-scale

0.955

High

625915

PSB2
Proteasome subunit beta type-2

7

19

Small-scale

0.952

High

619956

PSB6
Proteasome subunit beta type-6

6

20

Small-scale

0.941

High

675411

UMP1
Proteasome maturation factor UMP1

6

3

Small-scale

0.935

High

675424

BLM10
Proteasome activator BLM10

5

12

Small-scale

0.920

High

675397

PSA5
Proteasome subunit alpha type-5

5

20

Small-scale

0.912

High

675430

PRS8
26S proteasome regulatory subunit 8 homolog

3

20

Small-scale

0.817

High

675395

PSB5
Proteasome subunit beta type-5

2

20

High-throughput

0.776

High

675405

PRS6A
26S proteasome regulatory subunit 6A

2

20

High-throughput

0.754

High

675425

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

7

20

Small-scale

0.735

High

675417

RPN10
26S proteasome regulatory subunit RPN10

3

15

High-throughput

0.662

High

675446

RPN5
26S proteasome regulatory subunit RPN5

3

20

Small-scale

0.662

High

675414

ECM29
Proteasome component ECM29

3

11

Small-scale

0.624

High

675406

PRS6B
26S proteasome regulatory subunit 6B homolog

1

20

High-throughput

0.618

High

675407

PRS7
26S proteasome regulatory subunit 7 homolog

1

20

High-throughput

0.618

High

675423

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

High-throughput

0.618

High

675428

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

627777

SIS1
Protein SIS1

2

6

High-throughput

0.601

High

675445

RPN8
26S proteasome regulatory subunit RPN8

2

20

Small-scale

0.584

High

675436

POC1
Proteasome chaperone 1

1

3

High-throughput

0.553

High

675412

HSM3
DNA mismatch repair protein HSM3

2

0

Small-scale

0.551

High

636213

FUB1
Silencing boundary-establishment protein FUB1

2

3

High-throughput

0.549

High

675432

STD1
Protein STD1

1

0

High-throughput

0.518

High

549974

CSK21
Casein kinase II subunit alpha

1

10

High-throughput

0.515

High

618818

PP2A2
Serine/threonine-protein phosphatase PP2A-2 catalytic subunit

1

2

High-throughput

0.515

High

675408

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.514

High

565492

PHO85
Cyclin-dependent protein kinase PHO85

1

7

High-throughput

0.501

High

416762

CDC31
Cell division control protein 31

1

1

Small-scale

0.479

High

566142

EST1
Telomere elongation protein EST1

1

1

High-throughput

0.479

High

661552

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

675398

RPN12
26S proteasome regulatory subunit RPN12

1

6

High-throughput

0.479

High

675399

RPN2
26S proteasome regulatory subunit RPN2

1

20

High-throughput

0.479

High

675401

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

1

High-throughput

0.479

High

675403

RAD23
UV excision repair protein RAD23

1

20

Small-scale

0.479

High

675404

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

High-throughput

0.479

High

675409

POC2
Proteasome assembly chaperone 2

1

3

High-throughput

0.479

High

675415

RPN1
26S proteasome regulatory subunit RPN1

1

20

High-throughput

0.479

High

675419

RPN3
26S proteasome regulatory subunit RPN3

1

11

High-throughput

0.479

High

675429

APJ1
J domain-containing protein APJ1

1

5

High-throughput

0.479

High

675435

RPN9
26S proteasome regulatory subunit RPN9

1

16

High-throughput

0.479

High

675439

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

675447

RUVB2
RuvB-like protein 2

1

2

High-throughput

0.479

High

675427

POP6
Ribonucleases P/MRP protein subunit POP6

1

0

High-throughput

0.458

High

675434

OYE2
NADPH dehydrogenase 2

1

0

High-throughput

0.458

High

675431

UBC7
Ubiquitin-conjugating enzyme E2 7

1

6

High-throughput

0.457

High

365934

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

410216

UBC2
Ubiquitin-conjugating enzyme E2 2

1

6

Small-scale

0.445

High

490571

HSP71
Heat shock protein SSA1

1

7

High-throughput

0.445

High

549794

UBC4
Ubiquitin-conjugating enzyme E2 4

1

4

Small-scale

0.445

High

549850

UBC5
Ubiquitin-conjugating enzyme E2-16 kDa

1

4

Small-scale

0.445

High

600921

UBC1
Ubiquitin-conjugating enzyme E2 1

1

5

Small-scale

0.445

High

675400

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

4

Small-scale

0.445

High

675402

HSP79
Heat shock protein homolog SSE2

1

11

High-throughput

0.445

High

675420

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

675410

NU170
Nucleoporin NUP170

1

1

High-throughput

0.437

High

675418

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

2

High-throughput

0.437

High

675441

VAM6
Vacuolar morphogenesis protein 6

1

3

High-throughput

0.437

High

675416

CIC1
Proteasome-interacting protein CIC1

1

0

Small-scale

0.426

High

675433

RPN4
Protein RPN4

1

0

Small-scale

0.426

High

675444

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

Small-scale

0.426

High

477980

HSP77
Import motor subunit, mitochondrial

1

9

High-throughput

0.407

High

675437

HSP7Q
Iron-sulfur cluster biogenesis chaperone, mitochondrial

1

9

High-throughput

0.407

High

675442

VPS13
Intermembrane lipid transfer protein VPS13

1

0

High-throughput

0.269

Low

599342

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.249

Low

675438

RRG8
Required for respiratory growth protein 8, mitochondrial

1

0

High-throughput

0.249

Low

675440

GPI11
Glycosylphosphatidylinositol anchor biosynthesis protein 11

1

0

High-throughput

0.249

Low

539528

SAM35
Sorting assembly machinery 35 kDa subunit

1

0

High-throughput

0.238

Low

587293

UBR1
E3 ubiquitin-protein ligase UBR1

1

0

Small-scale

0.232

Low

675426

JAC1
J-type co-chaperone JAC1, mitochondrial

1

0

High-throughput

0.232

Low

675443

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024